Parsimonious versus extensive bleeding score: can we simplify risk stratification after percutaneous coronary intervention and reduce bleeding events by de-escalation of the antipl... by Pascal Vranckx, Stephan Windecker, Marco Valgimigli, Neil O’Leary, Yoshinobu Onuma, Peter Damman, Eva Christine Ida Woelders, Kai Ninomiya, Denise Adriana Maria Peeters, Arnoud Willem Johannes van 't Hof, Patrick Washington J C Serruys, Robert-Jan Matthijs van Geuns

“…We aimed to compare the predictive and prognostic value of the ‘Zuidoost Nederland Hart Registratie’ (ZON-HR) classification for bleeding risk with the PREdicting bleeding Complications In patients undergoing Stent implantation and subsEquent DAPT (PRECISE-DAPT) score and to determine the effect of ticagrelor monotherapy versus DAPT in patients with or without high bleeding risk (HBR).Methods A post hoc analysis of the GLOBAL LEADERS trial was performed to compare the predictive value of the ZON-HR classification with the PRECISE-DAPT score. …”
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Photosynthetic performance and carbon metabolism in the ear organs of oats under drought stress by Jiaqi Fang, Yuan Zhan, Baowen Zhao, Yan Zhao, Youjun Chen, Qingping Zhou, Hui Wang

“…Sufficiently exploiting the potential of crop photosynthesis is one of the critical ways for improving cultivation production to face global climate change. In this study, oat plants were potted with three watering treatments. …”
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Successful Achievement of Demanding Outcomes in Upadacitinib-Treated Atopic Dermatitis Patients: A Real-World, 96-Week Single-Centre Study by Stamatios Gregoriou, Ioannis-Alexios Koumprentziotis, Ileana Afroditi Kleidona, Michail Bakakis, Eleni Hatzidimitriou, Theodora Douvali, Aikaterini Tsiogka, Styliani Mastraftsi, Aristeidis Vaiopoulos, Alexander Stratigos

“…Clinical and patient-reported outcomes were recorded and assessed at each follow-up visit and included the eczema area severity index (EASI), investigator global assessment (IGA), scoring atopic dermatitis (SCORAD), dermatology life quality index (DLQI) and the worst pruritus numerical scale score (WP-NRS). …”
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Analysis of DNA cox1 barcoding revealed novel haplotype in Schistosoma haematobium isolated from Western Sudan by Ishraga Adam Elzain, Abeer Babiker Idris, Abdul Aziz Karim, Nagla Mohamed Ahmed, Salaheldein G. Elzaki, Semih Yılmaz, Mohamed A. Hassan, Hamid Suliman Abdalla

“…Abstract Schistosomiasis poses a significant global health threat, particularly in tropical and subtropical regions like Sudan. …”
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TLR4 Inhibition Attenuated LPS‐Induced Proinflammatory Signaling and Cytokine Release in Mouse Hearts and Cardiomyocytes by Christine W. Wiger, Trine Ranheim, Henriette Arnesen, Jarle Vaage, Søren E. Pischke, Arne Yndestad, Kåre‐Olav Stensløkken, May‐Kristin Torp

“…Isolated hearts, exposed to 35 min of global ischemia, were treated with either vehicle or CLI‐095 during reperfusion. …”
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Influence of diglyme and cumene additives upon emission and combustion behaviour of diverse biodiesel fuelled diesel engine by Swarup Kumar Nayak, Dinesh Babu Munuswamy, Ganesan Subbiah, Mallireddy Naresh, Yuvarajan Devarajan

“…The growing need for sustainable and eco-friendly fuels aligns with global efforts to achieve the United Nations Sustainable Development Goals (SDGs), particularly SDG 7 (Affordable and Clean Energy), SDG 13 (Climate Action), and SDG 12 (Responsible Consumption and Production). …”
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Advancing early detection of organ damage and cardiovascular risk prevention: the Suzhou cardiometabolic health study protocol - exploring the role of oral microbiome and metabolic... by Mengmeng Zhu, Mengmeng Zhu, Yiwen Li, Wenting Wang, Longkun Liu, Wenwu Liu, Jiayu Yu, Qian Xu, Jing Cui, Yanfei Liu, Keji Chen, Yue Liu, Yue Liu

“…BackgroundCardiovascular Disease (CVD) is the leading cause of global mortality, with its incidence rate rising year by year due to the prevalence of metabolic diseases. …”
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Association between migraine severity and sleep quality: a nationwide cross-sectional study by Nura A. Almansour, Nura A. Almansour, Seham S. Alsalamah, Seham S. Alsalamah, Razan S. Alsubaie, Razan S. Alsubaie, Nada N. Alshathri, Nada N. Alshathri, Yasmeen A. Alhedyan, Yasmeen A. Alhedyan, Faisal Y. Althekair’s, Faisal Y. Althekair’s, Faisal Y. Althekair’s

“…BackgroundMigraine is a primary headache disorder that affects more than 1 billion individuals globally and imposes a significant disability burden on society. …”
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Emergency Medicine Palliative Care Access (EMPallA): protocol for a multicentre randomised controlled trial comparing the effectiveness of specialty outpatient versus nurse-led tel... by Jeanne Cho, Michael Hill, Corita R Grudzen, Deborah J Shim, Abigail M Schmucker, Keith S Goldfeld, Lauren Southerland, Jeffrey M Caterino, Marie-Carmelle Elie, Robert Swor, Susan E Cohen, Arum Kim, Joseph Lowy, Jennifer S Scherer, Nancy E Bael, Ellin Gafford, Joshua Lakin, Paige Barker, Angela Chmielewski, Jennifer Kapo, Audrey Tan, Rebecca Yamarik, Susan Salz, Stephen Ryan, Anne Kim, Isabel Castro, Amelia Hargrove, Laura Stuecher, Nora Daut, Juanita Booker-Vaughns, Garrett K Chan, J Nicholas Dionne-odom, Patrick Dunn, Robert Galvin, Ernest A Hopkins III, Margaret M Maguire, Neha Reddy Pidatala, Dawn Rosini, Sally Welsh, Karen Jubanyik, Ada L Rubin, Kei Ouchi, Rebecca Murray, Nicole Tang, Marie Bakitas, Abraham Brody, Caroline Blaum, Mara Flannery, Richard Tamirian, Pamela Marsack, Jennifer Bonito, Romilla Batra, Donna C Sadasivan, Eric David Isaacs, Constance L Kizzie-Gillett, William K Vaughan, Pluscedia G Williams, Angela Young-Brinn

“…Eligible patients: (1) have advanced cancer (metastatic solid tumour) or end-stage organ failure (New York Heart Association class III or IV heart failure, end-stage renal disease with glomerular filtration rate <15 mL/min/m2, or global initiative for chronic obstructive lung disease stage III, IV or oxygen-dependent chronic obstructive pulmonary disease); (2) speak English; (3) are scheduled for ED discharge or observation status; (4) reside locally; (5) have a working telephone and (6) are insured. …”
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The impact of HPV/HIV co-infection on immunosuppression, HPV genotype, and cervical cancer biomarkers by Terkimbi Dominic Swase, Ilemobayo Victor Fasogbon, Ifie Josiah Eseoghene, Ekom Monday Etukudo, Solomon Adomi Mbina, Chebet Joan, Reuben Samson Dangana, Chinyere Anyanwu, Comfort Danchal Vandu, A. B Agbaje, Tijjani Salihu Shinkafi, Ibrahim Babangida Abubarkar, Patrick Maduabuchi Aja

“…Abstract Background Human papillomavirus (HPV) and human immunodeficiency virus (HIV) co-infection present a significant impact on women's health globally, especially in immunocompromised individuals. …”
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Genetic diversity and population structure of Plasmodium falciparum across areas of varied malaria transmission intensities in Uganda. by Mwesigwa, Alex, Tukwasibwe, Stephen, Cummings, Bryan, Kawalya, Hakiimu, Kiyaga, Shahiid, Okoboi, Stephen, Castelnuovo, Barbara, Bikaitwoha, Everd Maniple, Kalyango, Joan N., Nsobya, Samuel L., Karamagi, Charles, Byakika‑Kibwika, Pauline, Nankabirwa, Joaniter I.

“…Background: Malaria remains a significant global health threat, with sub-Saharan Africa (SSA) bearing the highest burden of the disease. …”
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Edge-centric connectome-genetic markers of bridging factor to comorbidity between depression and anxiety by Zhiyi Chen, Yancheng Tang, Xuerong Liu, Wei Li, Yuanyuan Hu, Bowen Hu, Ting Xu, Rong Zhang, Lei Xia, Jing-Xuan Zhang, Zhibing Xiao, Ji Chen, Zhengzhi Feng, Yuan Zhou, Qinghua He, Jiang Qiu, Xu Lei, Hong Chen, Shaozheng Qin, Tingyong Feng

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Características Epidemiológicas de Famílias e Pacientes com Câncer do Estado de São Paulo, suas Dificuldades e Desafios para Acesso ao Hospital de Câncer Infantojuvenil de Barret... by Denise Leonardi Queiroz Prado, Thaissa Maria Veiga Faria, Adeylson Guimarães Ribeiro, Luiz Fernando Lopes

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¿Puede la longitud cráneo-raquis predecir el tamaño cardíaco en embriones humanos? by Maria Aimée Vila Bormey, Yanely Surí Santos, Alfredo Santana Machado, Eliecer Anoceto Armiñana, Belkis Alfonso Águila

“…<strong>Fundamento:</strong> la longitud del embrión es una medición global, fácil de estimar y de interés como variable predictiva del tamaño alcanzado por los órganos internos en desarrollo.…”
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The integration of hospital pharmacists into primary care settings in Shenzhen, China: a qualitative study by Zhiling Deng, Pengxiang Zhou, Yiting Lu, Zhengrong Li, Mi Yao, Yang Li, Chuan Zou, Haixin Li, Songtao Cai, Yi Guo, Yuling Tong, Yang Zhao, Zhijie Xu

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Analysing DNA methylation and transcriptomic signatures to predict prostate cancer recurrence risk by Fahad M. Aldakheel, Hadeel Alnajran, Shatha A. Alduraywish, Ayesha Mateen, Mohammed S. Alqahtani, Rabbani Syed

“…Abstract Prostate cancer (PCa) remains a significant global health challenge, with approximately 1.6 million new cases and 366,000 deaths annually. …”
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Evaluation of the antidiarrheal activity of the 80% hydromethanolic crude extract and solvent fractions of Terminalia brownii Fresen (Combretaceae) leaves in Swiss Albino mice by Khalid Ibrahim Kassaw, Dawit Zewdu Wondafrash, Jibril Seid Yesuf, Mestayet Geta Mengistie

“…BackgroundAlthough diarrhea is a preventable disease, it continues to have a significant impact on global health, with the burden being much greater in Sub-Saharan Africa. …”
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Barriers and facilitators to data-based decision making in Australian early childhood education and care: A qualitative study by Shauna Sherker, Karen Villanueva, Ruth Beatson, Caitlin M. Macmillan, Wan Yi Lee, Olivia Hilton, Carly Molloy, Sharon Goldfeld

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Development and validation of a prediction model for acute kidney injury following cardiac valve surgery by Xiaotong Jia, Jun Ma, Zeyou Qi, Dongni Zhang, Junwei Gao

“…Patient demographics, including medical history and perioperative clinical information, were acquired, and patients were classified into one of two cohorts, AKI and non-AKI, according to the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines. Using binary logistic stepwise regression analysis, we identified independent AKI risk factors after cardiac valve surgery. …”
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Exploring Web-Based Support for Suicidal Ideation in the Scottish Population: Usability Study by Heather McClelland, Rory C O'Connor, Laura Gibson, Donald J MacIntyre

“… BackgroundSuicide is a global health concern. In the United Kingdom, Scotland has the highest suicide rate. …”
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