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Preoperative prediction of IDH genotypes and prognosis in adult-type diffuse gliomas: intratumor heterogeneity habitat analysis using dynamic contrast-enhanced MRI and diffusion-weighted imaging
Published 2025-02-01Subjects: “…Adult-type diffuse glioma…”
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Distinguishing glioblastoma from brain metastasis; a systematic review and meta-analysis on the performance of machine learning
Published 2025-02-01Subjects: Get full text
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Valproic acid targets IDH1 mutants through alteration of lipid metabolism
Published 2024-08-01“…Both VPA and a selective FASN inhibitor TVB-2640 rewired the lipidome and promoted apoptosis in an IDH1 MT but not in an IDH1 WT glioma cell line. We further find that HDACs are involved in the regulation of lipogenic genes and HDAC6 is particularly important for the regulation of FASN in IDH1 MT glioma. …”
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Cuproptosis-related lncRNAs and genes: Potential markers for glioblastoma prognosis and treatment.
Published 2025-01-01“…Despite the availability of various treatment options, glioblastoma (GBM) remains an extremely aggressive form of glioma with a poor prognosis. In recent studies, regulatory cell death (RCD) has been identified as an effective mechanism to suppress glioma. …”
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Identification and validation of TSPAN13 as a novel temozolomide resistance-related gene prognostic biomarker in glioblastoma.
Published 2025-01-01“…We assessed cell proliferation, migration, and invasion capabilities through in vitro assays (including CCK-8, Edu, wound healing, and transwell assays) and quantitatively analyzed TSPAN13 expression levels in clinical glioma samples using tissue microarray immunohistochemistry. …”
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