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A bird's eye view to the homeostatic, Alzheimer and Glioblastoma attractors
Published 2025-02-01Subjects: Get full text
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Near-infrared light triggered in situ release of CO for enhanced therapy of glioblastoma
Published 2023-02-01Subjects: Get full text
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Cuproptosis-related lncRNAs and genes: Potential markers for glioblastoma prognosis and treatment.
Published 2025-01-01“…Despite the availability of various treatment options, glioblastoma (GBM) remains an extremely aggressive form of glioma with a poor prognosis. …”
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Profiling the Secretome of Glioblastoma Cells Under Histone Deacetylase Inhibition Using Mass Spectrometry
Published 2025-02-01“…Glioblastoma (GBM) is the most aggressive brain tumor, and different efforts have been employed in the search for new drugs and therapeutic protocols for GBM. …”
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Neurocognitive function and health-related quality of life among glioblastoma patients: A prospective study
Published 2025-01-01Subjects: Get full text
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Synergistic strategies for glioblastoma treatment: CRISPR-based multigene editing combined with immune checkpoint blockade
Published 2025-02-01Subjects: “…Glioblastoma…”
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Multi-target and natural product-based multi-drug approach for anti-VEGF resistance in glioblastoma
Published 2024-09-01Subjects: “…glioblastoma…”
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Protein kinase inhibitors as targeted therapy for glioblastoma: a meta-analysis of randomized controlled clinical trials
Published 2025-02-01Subjects: “…Glioblastoma…”
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Identification and validation of TSPAN13 as a novel temozolomide resistance-related gene prognostic biomarker in glioblastoma.
Published 2025-01-01“…Glioblastoma (GBM) is the most lethal primary tumor of the central nervous system, with its resistance to treatment posing significant challenges. …”
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Mapping chromatin remodelling in glioblastoma identifies epigenetic regulation of key molecular pathways and novel druggable targets
Published 2025-02-01Subjects: “…Glioblastoma…”
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Distinguishing glioblastoma from brain metastasis; a systematic review and meta-analysis on the performance of machine learning
Published 2025-02-01“…Abstract Background The discrimination of glioblastoma and solitary metastasis brain tumor is challenging. …”
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Impact of developmental state, p53 status, and interferon signaling on glioblastoma cell response to radiation and temozolomide treatment.
Published 2025-01-01“…Glioblastoma (GBM) tumors exhibit extensive genomic, epigenomic, and transcriptional diversity, with significant intratumoral heterogeneity, complicating standard treatment approaches involving radiation (RT) and the DNA-alkylating agent temozolomide (TMZ). …”
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Escherichia coli combination with PD-1 blockade synergistically enhances immunotherapy in glioblastoma multiforme by regulating the immune cells
Published 2025-02-01Subjects: “…Glioblastoma…”
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Using DIMet for Differential Analysis of Labeled Metabolomics Data: A Step-by-step Guide Showcasing the Glioblastoma Metabolism
Published 2025-01-01“…Integrating metabolomics data with gene expression profiles further enriches the analysis, as we demonstrated in our prior study on glioblastoma metabolic symbiosis. However, the bioinformatics tools for analyzing tracer metabolomics data have been limited. …”
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Pooled screening for CAR function identifies novel IL-13Rα2-targeted CARs for treatment of glioblastoma
Published 2025-02-01“…Nonetheless, they are of particular interest for the treatment of glioblastoma, which is an aggressive form of brain cancer with few effective therapeutic options, due to their ability to cross the highly selective blood-brain barrier.Methods Here, we use our pooled screening platform, CARPOOL, to expedite the discovery of CARs with antitumor functions necessary for solid tumor efficacy. …”
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Anti-VEGF therapy improves EGFR-vIII-CAR-T cell delivery and efficacy in syngeneic glioblastoma models in mice
Published 2023-03-01“…Chimeric antigen receptor (CAR)-T cells have revolutionized the treatment of multiple types of hematological malignancies, but have shown limited efficacy in patients with glioblastoma (GBM) or other solid tumors. This may be largely due to the immunosuppressive tumor microenvironment (TME) that compromises CAR-T cells’ delivery and antitumor activity. …”
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Identification of m6A methyltransferase-related WTAP and ZC3H13 predicts immune infiltrates in glioblastoma
Published 2025-02-01Subjects: “…Glioblastoma…”
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Sophocarpine inhibits the proliferation and induces apoptosis of glioblastoma cells through regulating the miR-21/PTEN/PI3K/AKT axis
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Growth of the prefrontal cortical glioblastoma altered cognitive and emotional behaviors via mediating miRNAs and GABA-A receptor signaling pathways in rats
Published 2025-02-01“…The present study investigated the impact of GABAergic signaling and miRNA expression on glioblastoma multiforme (GBM) growth within the medial prefrontal cortex (mPFC) and its associated cognitive and emotional impairments. …”
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