A Literature Review and Case Report of Metastatic Pure Choriocarcinoma by Diwei Lin, Amanda Jia Hui Tan, Rajinder Singh-Rai

“…Testicular choriocarcinoma is one of the rarest variants of testicular germ cell tumours, accounting for less than 1% of testicular germ cell tumours and only about 0.19% of all testicular tumours. …”
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Insights from the single-cell level: lineage trajectory and somatic-germline interactions during spermatogenesis in dwarf surfclam Mulinia lateralis by Yajuan Li, Huilan Wei, Xiaoting Dai, Lijing Zhang, Liangjie Liu, Xiaomei Chen, Tian Liu, Ya Shu, Yaxin Yang, Shi Wang, Zhenmin Bao, Lingling Zhang

“…Conclusions This study provides a comprehensive single-cell transcriptome landscape of the gonad, which will contribute to the understanding of germ cell fate transition during spermatogenesis, and the development of germ cell manipulation technologies in mollusks.…”
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Mediastinal Teratoma with Neuroendocrine Features in 34-Year-Old Male with Syncope by Peter A. Andrawes, Masood A. Shariff, Qing Chang, Fanyi Kong, Frank M. Rosell

“…Somatic-type malignancy, defined as any sarcoma, carcinoma, leukemia, or lymphoma developing in a germ cell tumor, occurs in approximately 2% of all germ cell tumors. …”
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The glucose-sensing transcription factor MLX balances metabolism and stress to suppress apoptosis and maintain spermatogenesis. by Patrick A Carroll, Brian W Freie, Pei Feng Cheng, Sivakanthan Kasinathan, Haiwei Gu, Theresa Hedrich, James A Dowdle, Vivek Venkataramani, Vijay Ramani, Xiaoying Wu, Daniel Raftery, Jay Shendure, Donald E Ayer, Charles H Muller, Robert N Eisenman

“…Male germ cell (GC) production is a metabolically driven and apoptosis-prone process. …”
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Endobronchial Infection and Bacterial Lymphadenitis by Gemella morbillorum Leading to Airway Perforation and a Bronchopleural Fistula by Kaitlin N. DePrez, John Ferguson

“…Conclusion: In cases of severe mediastinal adenopathy in a young patient, bacterial lymphadenitis should be considered in the differential diagnosis with lymphoma, germ cell tumor, granulomatosis with polyangiitis, sarcoidosis, histoplasmosis, and inflammatory myofibroblastic tumor.…”
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Pediatric Ovarian Growing Teratoma Syndrome by Rebecca M. Rentea, Aaron Varghese, Atif Ahmed, Alexander Kats, Michelle Manalang, Tazim Dowlut-McElroy, Richard J. Hendrickson

“…Ovarian immature teratoma is a germ cell tumor that comprises less than 1% of ovarian cancers and is treated with surgical debulking and chemotherapy depending on stage. …”
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Choriocarcinoma Syndrome as an Initial Presentation of Testicular Cancer by Carlos Eduardo Salazar-Mejía, María Elena García-Gutiérrez, María Inés Contreras-Salcido, Carlos Javier Rodríguez-Álvarez, Blanca Otilia Wimer-Castillo, Jackeline Grace Lara-Campos, Edio Llerena-Hernández, José Luis González-Vela, David Hernández-Barajas

“…Histopathological study after right radical orchiectomy showed a mixed germ-cell tumor. Based on poor-risk characteristics, chemotherapy was started with an adequate clinical response. …”
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DNA methylation modulates nucleosome retention in sperm and H3K4 methylation deposition in early mouse embryos by Grigorios Fanourgakis, Laura Gaspa-Toneu, Pavel A. Komarov, Panagiotis Papasaikas, Evgeniy A. Ozonov, Sebastien A. Smallwood, Antoine H. F. M. Peters

“…Abstract In the germ line and during early embryogenesis, DNA methylation (DNAme) undergoes global erasure and re-establishment to support germ cell and embryonic development. While DNAme acquisition during male germ cell development is essential for setting genomic DNA methylation imprints, other intergenerational roles for paternal DNAme in defining embryonic chromatin are unknown. …”
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Primary Dysgerminoma of the Uterine Cervix: A Rare Case Report by Biruck Gashawbeza, Bethel Dereje, Ferid A. Abubeker

“…Primary extragonadal germ cell tumors (EGCTs) are a very rare clinical encounter most commonly reported in males. …”
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Mechanism of abnormal specification of spermatogonial stem cells after Rb1 knockout in mitotic-arrested prospermatogonia by CHEN Xinling, CHEN Xinling, LONG Yixuan, DU Guihua, DU Guihua

“…After that， flow cytometry was applied to divide the ID4-GFP cells into 3 communities based on the GFP fluorescence intensity， and then detect the number of cells and cell cycle in each community. ③ Germ cell proliferation （Ki67 positive， Ki67+）， SSCs specification （FOXO1 nuclear transition）， and germ cell differentiation （STRA8+） were detected with immunofluorescence staining. ④ TUNEL staining was utilized to detect cell apoptosis. …”
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Spatiotemporal dynamics of early oogenesis in pigs by Wei Ge, Yi-Lin Niu, Yu-Kang Li, Li Li, Han Wang, Wen-Wen Li, Tian Qiao, Yan-Ni Feng, Yu-Qing Feng, Jing Liu, Jun-Jie Wang, Xiao-Feng Sun, Shun-Feng Cheng, Lan Li, Wei Shen

“…Results Here, we integrate single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) to comprehend spatial–temporal gene expression profiles and explore the spatial organization of ovarian microenvironments during early oogenesis in pigs. Projection of the germ cell clusters at different stages of oogenesis into the spatial atlas unveils a “cortical to medullary (C-M)” distribution of germ cells in the developing porcine ovaries. …”
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Advanced Ovarian Dysgerminoma Infiltrating Both Ovaries and Uterus in a 7-Year-Old Girl by Nexhmi Hyseni, Sadik Llullaku, Hysni Jashari, Kaltrina Zahiti, Fjolla Hyseni, Fisnik Kurshumliu, Lumturije Luci, Fehim Muqolli, Antigona Hasani

“…Ovarian dysgerminoma is a rare malignant ovarian germ cell tumor with its peak incidence in young women. …”
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Mature Cystic Teratoma of the Ovary; Clinicopathological Evaluation of 143 Cases in our Series, 5 Years Experience by Ferah Kazanci, Betul Ogut, Dilek Yapar, Ozlem Erdem, M. Anil Onan

“… OBJECTIVE: Mature cystic teratoma, also known as a dermoid cyst, is the most common germ cell tumor of the ovary. In this retrospective study, it is aimed to evaluate clinicopathological findings of the patients who were operated on due to the preliminary diagnosis of dermoid cyst. …”
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Mature Teratoma Combined with Bladder Stones: A Case Report and Literature Review by Li A, Wang X, Wang C, Song Q, Niu Y, Wang P, Yue J

“…Anan Li,1 Xiaobo Wang,2 Chang Wang,2 Qingling Song,3 Yanbin Niu,1 Peng Wang,4 Juntao Yue5 1Department of Urology, 985th Hospital of People’s Liberation Army Joint Logistic Support Force, Taiyuan, Shanxi, People’s Republic of China; 2Department of Gastroenterology, 985th Hospital of People’s Liberation Army Joint Logistic Support Force, Taiyuan, Shanxi, People’s Republic of China; 3Department of Laboratory and Pathology, Lintong Rehabilitation Center of Joint Logistics Support Force of People’s Liberation Army, Lintong, Shaanxi, People’s Republic of China; 4Department of Pathology, 985th Hospital of People’s Liberation Army Joint Logistic Support Force, Taiyuan, Shanxi, People’s Republic of China; 5Reproductive Andrology and Human Sperm Bank, Key Laboratory of Obstetric, Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of ChinaCorrespondence: Juntao Yue, Reproductive Andrology and Human Sperm Bank, Key Laboratory of Obstetric, Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second University Hospital, Sichuan University, No. 1416 Chenglong Avenue, Jinjiang District, Chengdu, Sichuan, People’s Republic of China, Tel +86 02888570175, Email 2622958466@qq.comAbstract: Teratoma is neoplasia originating from a germ cell, which usually contains identifiable tissue derived from all three germ cell layers. …”
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Meningothelial Meningioma Component in a Prepubertal Testicular Teratoma by Ruchi Sinha, Madhu Kumari, Ranwir Kumar Sinha, Bindey Kumar

“…Teratomas are nonseminomatous germ cell tumors composed of elements derived from more than one germinal layers (endoderm, mesoderm, and ectoderm). …”
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Diagnosis and Surgical Management of Congenital Intranasal Teratoma in a Newborn: A Rare Case Report by W. X. Yeo, K. K. Tan

“…Teratomas are the most common germ cell tumors of childhood. Head and neck teratomas, however, account for less than five percent of all teratomas. …”
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Mature Ovarian Teratoma: Atypical Imaging by S. Wakrim, M. EL Jdid

“…., 2009), which is composed of well-differentiated tissues that derive from all three germ cell layers (ectoderm, mesoderm, and endoderm); it is one of the most common benign ovarian neoplasms. …”
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Growing Teratoma Syndrome: A Rare Outcome by João Rebelo, Francisco Moreira, Margarida Morgado, Ana Sofia Preto, António Madureira

“…We present a case of a 26-year-old male with known mixed germ cell tumor which exhibited new and progressive secondary lesions during imaging surveillance, later to be histologically characterized as teratomas.…”
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Cutaneous Manifestation of Metastatic Infantile Choriocarcinoma by Timothy Brooks, Laura Nolting

“…Infantile choriocarcinoma is a highly malignant rare germ cell tumor that arises from the placenta. Simultaneous intraplacental choriocarcinoma involving both mother and infant is extremely rare. …”
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Changing trends from inguinal radical orchiectomy to testis-sparing surgery in pediatric testicular tumors by Özlem Balcı, Aslı Nur Abay, Şule Yeşil, İbrahim Karaman, İsmet Faruk Özgüner, Burçak Kurucu, Derya Erdoğan, Gürses Şahin, Ayşe Karaman

“…Twenty-four of them were germ-cell tumors, and 79.2% of these patients were prepubertal. …”
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