Showing 361 - 380 results of 686 for search '"genomes"', query time: 0.07s Refine Results
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    Multi-locus CRISPRi targeting with a single truncated guide RNA by Molly M. Moore, Siddarth Wekhande, Robbyn Issner, Alejandro Collins, Anna J. Cruz, Yanjing V. Liu, Nauman Javed, Salvador Casaní-Galdón, Jason D. Buenrostro, Charles B. Epstein, Eugenio Mattei, John G. Doench, Bradley E. Bernstein, Noam Shoresh, Fadi J. Najm

    Published 2025-02-01
    “…Abstract A critical goal in functional genomics is evaluating which non-coding elements contribute to gene expression, cellular function, and disease. …”
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    Article
  4. 364

    Infectious disease phylodynamics with occurrence data by Leo A. Featherstone, Francesca Di Giallonardo, Edward C. Holmes, Timothy G. Vaughan, Sebastián Duchêne

    Published 2021-08-01
    “…Abstract Phylodynamic models use pathogen genome sequence data to infer epidemiological dynamics. …”
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    Article
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    The distribution of allele frequencies of the 15 Short Tandem Repeats loci in Elazığ population, Turkiye by Aziz Aksoy, Mehmet Tokdemi̇r, Vahit Konar

    Published 2024-04-01
    “…The DNA within the Human Genome involves loci with high polymorphism such as short tandem repeats (STR). …”
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    Article
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    Opportunities for promoting open data in the Caribbean through biobanks by Sushant Saluja, Simon G. Anderson

    Published 2025-02-01
    “…It offers unprecedented insights into health data through extensive follow up and collection of genome-wide genotype data. H3Africa focuses on genomics research that addresses health disparities among African populations, which parallels the Caribbean’s challenges. …”
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    Article
  9. 369

    Chronic wounds and adaptive Pseudomonas aeruginosa: A phenotypic and genotypic characterization by Kasandra Buchholtz, Rie Jønsson, Rasmus L. Marvig, Biljana Mojsoska, Karen Angeliki Krogfelt

    Published 2025-01-01
    “…This was performed using genomic and phenotypic approaches to understand the survival and persistence of Pseudomonas strains. …”
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    Article
  10. 370

    Galloping into the Future: Genetic Tips and Tools for the Horse Owner by Laura Patterson Rosa, Carissa Wickens, Samantha A. Brooks

    Published 2017-06-01
    “… This 4-page fact sheet discusses the equine genome, determining the genotype of a horse, breeding for certain traits, and the future of genetic tools. …”
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    Article
  11. 371

    Galloping into the Future: Genetic Tips and Tools for the Horse Owner by Laura Patterson Rosa, Carissa Wickens, Samantha A. Brooks

    Published 2017-06-01
    “… This 4-page fact sheet discusses the equine genome, determining the genotype of a horse, breeding for certain traits, and the future of genetic tools. …”
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    Article
  12. 372

    Overcoming immunotherapy resistance in gastric cancer: insights into mechanisms and emerging strategies by Dingtian Luo, Jing Zhou, Shuiliang Ruan, Binzhong Zhang, Huali Zhu, Yangming Que, Shijie Ying, Xiaowen Li, Yuanmin Hu, Zhengwei Song

    Published 2025-02-01
    “…We also discuss emerging strategies to overcome resistance, including combination therapies, novel immunotherapeutic approaches, and personalized treatment strategies based on tumor genomics and the immune microenvironment. By highlighting these key areas, this review aims to inform future research directions and clinical practice, ultimately improving outcomes for GC patients undergoing immunotherapy.…”
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  13. 373

    The impact of social complexity on the efficacy of natural selection in termites by Roux, Camille, Ha, Alice, Weyna, Arthur, Lode, Morgan, Romiguier, Jonathan

    Published 2024-10-01
    “…In this study, we investigate the genomic consequences of eusociality in termites (Isoptera) on two different timescales. …”
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    Simultaneous Inference of Past Demography and Selection from the Ancestral Recombination Graph under the Beta Coalescent by Korfmann, Kevin, Sellinger, Thibaut Paul Patrick, Freund, Fabian, Fumagalli, Matteo, Tellier, Aurélien

    Published 2024-03-01
    “…The reproductive mechanism of a species is a key driver of genome evolution. The standard Wright-Fisher model for the reproduction of individuals in a population assumes that each individual produces a number of offspring negligible compared to the total population size. …”
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    Protein arginine methyltransferase 7 linked to schizophrenia through regulation of neural progenitor cell proliferation and differentiation by Ting Shen, Jing Yu, Bin Xie, Cuiping Huang, Jingjie Cui, Kefu Liu, Chunyu Liu, Chao Chen

    Published 2025-02-01
    “…Summary: Genome-wide association studies (GWASs) have identified numerous genomic loci linked to schizophrenia (SCZ), while their pathogenic mechanisms largely remain unclear. …”
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  18. 378

    Global biogeography and projection of antimicrobial toxin genes by Ya Liu, Yu Geng, Yiru Jiang, Jingyu Sun, Peng Li, Yue-zhong Li, Zheng Zhang

    Published 2025-02-01
    “…Results Here, we identified 4400 ATG clusters from 149 families by correlating 10,000 samples worldwide with over 200,000 microbial genome data. We demonstrated that global microbial communities universally encode complex and diverse ATGs, with widespread differences across various habitats. …”
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    Hairy transcriptional repression targets and cofactor recruitment in Drosophila. by Daniella Bianchi-Frias, Amir Orian, Jeffrey J Delrow, Julio Vazquez, Alicia E Rosales-Nieves, Susan M Parkhurst

    Published 2004-07-01
    “…This approach identified 40 novel genomic targets for Hairy in Kc cells, as well as 155 loci recruiting Groucho, 107 loci recruiting dSir2, and wide genomic binding of dCtBP to 496 loci. …”
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