Showing 281 - 300 results of 5,161 for search '"genome"', query time: 0.10s Refine Results
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    Characterizations of cytokines and viral genomes in serum of patients with Dabie bandavirus infection by Zefeng Dong, Man Yuan, Yueping Xing, Hongkai Zhang, Qiang Shen

    Published 2025-01-01
    “…The cytokine concentrations in serum were detected by micro enzyme-linked immunosorbent assay (ELISA). The genomes of Dabie bandavirus were amplified using a designated primer pool. …”
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    Genome-wide association study unravels mechanisms of brain glymphatic activity by Shu-Yi Huang, Yi-Jun Ge, Peng Ren, Bang-Sheng Wu, Weikang Gong, Jing Du, Shi-Dong Chen, Ju-Jiao Kang, Qing Ma, Arun L. W. Bokde, Sylvane Desrivières, Hugh Garavan, Antoine Grigis, Herve Lemaitre, Michael N. Smolka, Sarah Hohmann, IMAGEN Consortium, Jian-Feng Feng, Ya-Ru Zhang, Wei Cheng, Jin-Tai Yu

    Published 2025-01-01
    “…Here, we identified 17 unique genome-wide significant loci and 161 candidate genes linked to the ALPS-indexes in a discovery sample of 31,021 individuals from the UK Biobank. …”
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    Chromosome-level genome assembly of tetraploid Chinese cherry (Prunus pseudocerasus) by Wei Zhang, Jing Wang, Xuncheng Wang, Xuwei Duan, Junbo Peng, Xiaoming Zhang, Qikai Xing, Kaichun Zhang, Jiye Yan

    Published 2025-01-01
    “…However, disease resistance resources of ‘Duiying’ have not been fully exploited partially due to the lack of a high-quality genome. In this study, we report a high-quality chromosome-scale genome assembly for Chinese cherry ‘Duiying’, by combining PacBio HiFi, Bionano and Hi-C sequencing data. …”
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    Genomic and algorithm-based predictive risk assessment models for benzene exposure by Minyun Jiang, Minyun Jiang, Na Cai, Na Cai, Juan Hu, Lei Han, Lei Han, Fanwei Xu, Baoli Zhu, Baoli Zhu, Baoli Zhu, Baoli Zhu, Boshen Wang

    Published 2025-01-01
    “…AimIn this research, we leveraged bioinformatics and machine learning to pinpoint key risk genes associated with occupational benzene exposure and to construct genomic and algorithm-based predictive risk assessment models.Subject and methodsWe sourced GSE9569 and GSE21862 microarray data from the Gene Expression Omnibus. …”
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    Chromosome-level reference genome assembly for the mountain hare (Lepus timidus) by Fekete, Zsófia, Absolon, Dominic E., Michell, Craig, Wood, Jonathan M. D., Goffart, Steffi, Pohjoismäki, Jaakko L. O.

    Published 2025-01-01
    Subjects: “…Lagomorpha, reference genome, chromosome structure, phylogeny, fibroblast cell line…”
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    Widespread mutagenesis and chromosomal instability shape somatic genomes in systemic sclerosis by Sriram Vijayraghavan, Thomas Blouin, James McCollum, Latarsha Porcher, François Virard, Jiri Zavadil, Carol Feghali-Bostwick, Natalie Saini

    Published 2024-10-01
    “…We find an overall increase in all major mutation types in systemic sclerosis samples compared to control lung samples, from small-scale events such as single base substitutions and insertions/deletions, to chromosome-level changes, including copy-number changes and structural variants. In the genomes of patients with systemic sclerosis, we find evidence of somatic hypermutation or kategis (typically only seen in cancer genomes), we identify mutation signatures closely resembling the error-prone translesion polymerase Polη activity, and observe an activation-induced deaminase-like mutation signature, which overlaps with genomic regions displaying kataegis.…”
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