Neoadjuvant immunotherapy for DNA mismatch repair proficient/microsatellite stable non-metastatic rectal cancer: a systematic review and meta-analysis by Huan Zhang, Jing Huang, Huanji Xu, Nanhao Yin, Nanhao Yin, Liyan Zhou, Liyan Zhou, Jianxin Xue, Jianxin Xue, Jianxin Xue, Min Ren

“…The relatively small sample size and the uneven quality of included studies may have had some impact on the generality of the results. Therefore, further analysis with a higher number of high-quality studies is needed to verify the conclusions.Systematic review registrationhttps://inplasy.com/, identifier: INPLASY202470110.…”
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OXA β-lactamases from Acinetobacter spp. are membrane bound and secreted into outer membrane vesicles by Lucia Capodimonte, Fernando Teixeira Pinto Meireles, Guillermo Bahr, Robert A. Bonomo, Matteo Dal Peraro, Carolina López, Alejandro J. Vila

“…ABSTRACT β-lactamases from Gram-negative bacteria are generally regarded as soluble, periplasmic enzymes. …”
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Rainwater and fog harvesting from solar panels by I. Alazzam, K. Shatanawi, R. Al-Weshah

“…These relationships can be generalized to provide an estimation for the quantity of rainwater and fog harvesting in other locations. …”
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Effect of Planting Systems on the Physicochemical Properties and Bioactivities of Strawberry Polysaccharides by Qiuqiu Zhang, Renshuai Huang, Guangjing Chen, Fen Guo, Yan Hu

“…Biological activity assays revealed that GP-SP generally exerted stronger non-enzymatic glycation inhibition at both early and final stages (IC₅₀: 7.47 mg/mL vs. 7.82 mg/mL and 11.18 mg/mL vs. 11.87 mg/mL, respectively), whereas EP-SP was more effective against intermediate α-dicarbonyl compounds (maximum inhibition of 75.32%). …”
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PENERAPAN MODEL PROJECT BASED LEARNING UNTUK MENINGKATKAN LITERASI SAINS MAHASISWA PENDIDIKAN IPA by Indra Sakti, nirwana nirwana, Eko Swistoro

“…Kata Kunci : Model Project Based Learning, Literasi Sains   ABSTRACT   Classroom Action Research was carried out by applying the Project Based Learning (PjBL) model in the Science Education Study Program FKIP Bengkulu University in 2020 in the IPA-3 course. This research generally aimed to improve the science literacy of science teacher student candidates. …”
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Differential management and associations of dyslipidaemia and hypertension by glycaemic status in urban South Africans by N Peer, L Kotzé-Hörstmann, J Hill, A-P Kengne

“…Sociodemographic and cardiovascular disease risk factors were generally not associated with hypertension or dyslipidaemia management. …”
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Four weeks of slow-paced breathing: a longitudinal, randomized, placebo-controlled study of the autonomic nervous system by Nicolas Bourdillon, Arnaud Rochat, Vanessa Hoop, Grégoire P. Millet

“…These specific benefits were generally significant from week 4 onward. Further studies are required to better explore the underlying mechanisms. …”
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Physiology and Pathophysiology of Marathon Running: A narrative Review by Lorin Braschler, Pantelis T. Nikolaidis, Mabliny Thuany, Daniela Chlíbková, Thomas Rosemann, Katja Weiss, Matthias Wilhelm, Beat Knechtle

“…Conclusion All in all, marathon training is generally safe for human health and individual organ systems. …”
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95-95-95 HIV indicators among children younger than 15 years in South Africa: results from the 2017 national HIV prevalence, incidence, behaviour, and communication survey by Rindidzani E. Magobo, Musawenkosi Mabaso, Sean Jooste, Lesiba Molopa, Inbarani Naidoo, Leickness Simbayi, Khangelani Zuma, Nompumelelo Zungu, Olive Shisana, Sizulu Moyo

“…Backward stepwise multivariable generalized linear regression models were fitted to identify factors associated with the 95-95-95 HIV indicators. …”
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Exploring the Dynamics of Brent Crude Oil, S&P500 and Bitcoin Prices Amid Economic Instability by Adela Bara, Irina Alexandra Georgescu, Simona-Vasilica Oprea, Marian Pompiliu Cristescu

“…This paper conducts an extensive examination of the forecasting capabilities of various GARCH (Generalized Autoregressive Conditional Heteroskedasticity) models, identifying the most suitable GARCH model for estimating Value at Risk (VaR) for Brent crude oil price. …”
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Planificación del desarrollo en Argentina. Una agenda de avances y desafíos abiertos (2003-2015) by Ariel Oscar García

“…En ese contexto histórico, han vuelto a resultar interrogantes pertinentes para la gestión pública qué, quienes, cómo, cuánto y donde se produce, así como cuáles son las modalidades de distribución y acumulación. En términos generales, las políticas regionales y sectoriales de promoción se han caracterizado por la dispersión y superposición de entidades que entienden en la materia. …”
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Relationships between paddock-level pasture mass and cow data derived from GPS and behavior-monitoring on-animal sensors in rotationally grazed dairy systems by S.J. Hendriks, M. Qasim, J.P. Edwards

“…., rumination, grazing, or eating data) were generally poorer performers. Our results demonstrate the additional value that location-based data can provide. …”
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Short-term effects of combined environmental factors on respiratory disease mortality in Qingdao city: A time-series investigation. by Xin Zhang, Zijian Xi, Min Yang, Xiuqin Zhang, Ruikai Wu, Shuang Li, Lu Pan, Yuan Fang, Peng Lv, Yan Ma, Haiping Duan, Bingling Wang, Kunzheng Lv

“…The distributed-lag nonlinear model and generalized additivity model were used to assess the association between daily mean temperature (DMT), air pollutant exposure and RD mortality. …”
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AiGPro: a multi-tasks model for profiling of GPCRs for agonist and antagonist by Rahul Brahma, Sunghyun Moon, Jae-Min Shin, Kwang-Hwi Cho

“…Scientific Contribution We introduce a deep learning-based multi-task model to generalize the agonist and antagonist bioactivity prediction for GPCRs accurately. …”
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Effect of JumpstartMD, a Commercial Low-Calorie Low-Carbohydrate Physician-Supervised Weight Loss Program, on 22,407 Adults by Sean Bourke, John Magaña Morton, Paul Williams

“…JumpstartMD produced generally greater weight loss than published reports for other real-food and prepackaged-meal commercial programs and somewhat greater or comparable losses to meal replacement diets. …”
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April 15th war and hemodialysis patients in Sudan: a cross-sectional study by Malaz Hassan Dafaalla Idrees, Moez Mohammed Ibrahim Bashir, Balqees Abdeen Ahmed Mohamed, Amal Essam Ali Ahmed, Hamid Mohieldin Mohamed Abdalla, Kamil Mirghani Ali Shaaban

“…The questionnaire encompassed five primary domains: demographic data, healthcare access (Levesque’s Conceptual Framework of Access), physical implications, psychological impact (Generalized Anxiety Disorder scale and Patient health questionnaire), and quality of life (Kidney disease quality of life 36 scales). …”
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Experimental Investigation on Shear Strength between Ultra-High-Performance Concrete and Normal Concrete Substrates by Xinghong Jiang, Hengxiang Song, Ke Li, Jing Qiang, Jing Tian

“…The shear strength of the prefabricated UHPC-post-pouring NC interface is generally low, and the maximum shear strength of 13.9 MPa obtained by the test is still lower than the recommended value of 14–21 MPa of ACI 546.3R-14. …”
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Evaluation and Management of Patients with Seizures in the Emergency Department: A One-Year Analysis by K. Puteikis, K. Zdanytė, R. Mameniškienė

“…Focal seizures (32, 59.3%) and alcohol-related metabolic seizures (8, 14.8%) were most common with epilepsy; unknown or unspecified (22, 68.8%) and generalized (6, 18.8%) – with new-onset seizures. For outpatients with epilepsy, alcohol abstinence (16, 44.4%) and everyday (lifestyle, work etc.) recommendations (13, 36.1%) were most common, treatment was often modified (14, 38.9%). …”
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Electroporation and GFP-labelled transplantation of testicular cells in Nile tilapia by Epro Barades, , Alimuddin, Agus Oman Sudrajat

“…A donor germinal cells that was used in transplantation are labeled to distinguish it with endogenous cells. Donor cells are generally derived from transgenic fish carrying a marker or cells labeled by PKH-26. …”
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Assessment of Some Physicochemical Parameters and Heavy Metals in Hand-Dug Well Water Samples of Kafta Humera Woreda, Tigray, Ethiopia by Kiros Gebremichail Gebresilasie, Goitom Gebreyohannes Berhe, Amanual Hadera Tesfay, Samuel Estifanos Gebre

“…The results showed that the physicochemical concentrations of the hand-dug well water samples were given as follows: temperature, 27.67 ± 0.15 to 28.30 ± 0.25°C; pH, 6.90 ± 0.33 to 8.20 ± 0.36; dissolved oxygen, 5.60 ± 0.06 to 6.2 ± 0.04 mg/L; turbidity, 1.67 ± 0.02 to 1.89 ± 0.03 NTU; EC, 148.50 ± 0.89 to 932.00 ± 0.98 μS/cm; TDS, 105.80 ± 0.62 to 664.28 ± 0.70 mg/L; total hardness, 71.80 ± 3.05 to 295.30 ± 2.38 mg/L; total alkalinity, 75 ± 5.0 to 215 ± 5.0 mg/L; calcium, 12.02 ± 0.82 to 75.88 ± 0.93 mg/L; magnesium, 9.80 ± 0.80 to 25.70 ± 0.17 mg/L; potassium, 0.130 ± 0.003 to 0.86 ± 0.04 mg/L; sodium, 2.20 ± 0.16 to 12.75 ± 0.87 mg/L; chloride, 12.86 ± 0.02 to 42.72 ± 0.20 mg/L; sulfate, 17.24 ± 0.96 to 118.67 ± 0.46 mg/L; phosphate, 0.018 ± 0.005 to 0.020 ± 0.002 mg/L; and nitrate, 1.86 ± 0.03 to 5.43 ± 0.06 mg/L. Generally, the concentrations of most physicochemical parameters of the hand-dug well water samples of Kafta Humera Woreda were within the permissible limit of World Health Organization and Ethiopian Standard Agency guideline for drinking water. …”
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