Clinical Trials of Immunogene Therapy for Spontaneous Tumors in Companion Animals by Gerardo Claudio Glikin, Liliana María Elena Finocchiaro

“…The encouraging outcomes obtained in companion animals support their ready application in veterinary clinical oncology and serve as preclinical proof of concept and safety assay for future human gene therapy trials.…”
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Epidermolysis bullosa by Anđelić Slađana, Stefanović Ivana, Tasić-Uroš Danijela, Milivojčević- Bevc Ivana, Savić Nikola

“…Without curative therapy, treatment is oriented towards supportive care, symptom control, and preventing mild to severe complications. Vector gene therapy Vyjuvek (beremagene geperpavec), based on the herpes simplex virus type 1, is a new hope for treating wounds in patients older than six months who suffer from dystrophic forms of EB.…”
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Role of B-Cell Lymphoma/Leukemia 11A in Normal and Malignant Hematopoiesis by Haihang Zhang, Junhao Zeng, Fangling Zhang, Jing Liu, Long Liang

“…B-cell lymphoma/leukemia 11A (BCL11A) is a crucial transcriptional regulator, widely recognized for its role in controlling fetal hemoglobin and its potential as a gene therapy target for inherited hemoglobinopathies. …”
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Targeted Anticancer Immunotoxins and Cytotoxic Agents with Direct Killing Moieties by Koji Kawakami, Oumi Nakajima, Ryuichi Morishita, Ryozo Nagai

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Dendrimers as Carriers for siRNA Delivery and Gene Silencing: A Review by Jiangyu Wu, Weizhe Huang, Ziying He

“…RNA interference (RNAi) was first literaturally reported in 1998 and has become rapidly a promising tool for therapeutic applications in gene therapy. In a typical RNAi process, small interfering RNAs (siRNA) are used to specifically downregulate the expression of the targeted gene, known as the term “gene silencing.” …”
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From Lab to Clinic: Effect of Academia–Industry Collaboration Characteristics on Oncology Phase 1 Trial Entry by Wonseok Yang, Sang‐Won Lee

“…For discovery stage contracts, strong statistical significance was observed for contract type (co‐development OR 16.45, p = 0.008; licensing OR 42.43, p = 0.000) and technology (cell or gene therapy OR 3.82, p = 0.008). In contrast, for preclinical stage contracts, significant changes were noted for cancer type (blood cancer OR 2.24, p = 0.004), while the year of contract signing showed a relatively weak statistical significance (OR 1.24, p = 0.021). …”
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The Tao of Hematopoietic Stem Cells: Toward a Unified Theory of Tissue Regeneration by Kevin D. Bunting, Robert G. Hawley

“…Therefore, HSCs are extremely important targets for gene therapy applications aimed toward the treatment of inherited and acquired blood disorders. …”
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Human Cardiospheres as a Source of Multipotent Stem and Progenitor Cells by Lucio Barile, Mihaela Gherghiceanu, Laurenţiu M. Popescu, Tiziano Moccetti, Giuseppe Vassalli

“…Whether or not CDCs are superior to purified populations, for example, c-kit+ cardiac stem cells, or to gene therapy approaches for cardiac regeneration remains to be evaluated.…”
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Fractional-Order PI Control of First Order Plants with Guaranteed Time Specifications by F. J. Castillo-Garcia, A. San Millan-Rodriguez, V. Feliu-Batlle, L. Sanchez-Rodriguez

“…Whether or not CDCs are superior to purified populations, for example, c-kit+ cardiac stem cells, or to gene therapy approaches for cardiac regeneration remains to be evaluated.…”
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Bioinformatic Analysis of PTTG Family and Prognosis and Immune Cell Infiltration in Gastric Cancer by Xiao Li, Yanghao Tai, Shuying Liu, Yating Gao, Kaining Zhang, Jierong Yin, Huijuan Zhang, Xia Wang, Xiaofei Li, Dongfeng Zhang

“…Adaptive cell therapy, cancer vaccines, gene therapy, and monoclonal antibody therapy have all been used in gastric cancer with some initial success. …”
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Large-scale manufacturing and characterization of CMV-CD19CAR T cells by Stephen J Forman, Xiuli Wang, Ryan Urak, Miriam Walter, Min Guan, Tianxu Han, Vibhuti Vyas, Sheng-Hsuan Chien, Brenna Gittins, Mary C Clark, Sally Mokhtari, Angelo Cardoso, Don J Diamond, John Zaia, Ryotaro Nakamura

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Differential Signature of the Centrosomal MARK4 Isoforms in Glioma by Ivana Magnani, Chiara Novielli, Laura Fontana, Silvia Tabano, Davide Rovina, Ramona F. Moroni, Dario Bauer, Stefania Mazzoleni, Elisa A. Colombo, Gabriella Tedeschi, Laura Monti, Giovanni Porta, Silvano Bosari, Carolina Frassoni, Rossella Galli, Lorenzo Bello, Lidia Larizza

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Assessing traditional Chinese medicine from a molecular perspective by Minhui Su, Wenxi Wang, Xudong Sun, Lihong Li, Weihong Tan

“…Nucleic acids, a class of star functional molecules, are notable for their versatile applications in molecular diagnostics, gene therapy, and drug development. Therefore, in this study, we review the extensive use of nucleic acid aptamers in medicinal practice. …”
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Magnetic Nanoparticles of Chitosan for Targeted Delivery System of Plasmids to the Lungs by Cynthia Aracely Alvizo Báez, Itza Eloisa Luna Cruz, Maria Cristina Rodríguez Padilla, Juan Manuel Alcocer González

“…One of the major problems of gene therapy is the efficient, specific, and targeted delivery as well as the safety of the materials used in such systems. …”
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A Systematic Literature Review and Bibliometric Analysis of Ophthalmology and COVID-19 Research by Ali Forouhari, Vahid Mansouri, Sare Safi, Hamid Ahmadieh, Amir Ghaffari Jolfayi

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Glycogen Storage Disease Type IX in a 6-year-old Male: A Case Report by Shahab Noorian, Hossein Moravej, Zhila Afshar, Afagh Hassanzadeh Rad, Setila Dalili

“…Conclusions: Future therapies, such as gene therapy and enzyme replacement, aim to address the root causes of GSDs rather than merely managing symptoms. …”
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Erratum to “DNMT3A Mutations in Patients with Acute Myeloid Leukemia in South Brazil” by Annelise Pezzi, Lauro Moraes, Vanessa Valim, Bruna Amorin, Gabriela Melchiades, Fernanda Oliveira, Maria Aparecida da Silva, Ursula Matte, Maria S. Pombo-de-Oliveira, Rosane Bittencourt, Liane Daudt, Lucia Silla

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Hydrogel-based nanoparticles: revolutionizing brain tumor treatment and paving the way for future innovations by Alireza Shadab, Simin Farokhi, Arshia Fakouri, Neda Mohagheghzadeh, Ali Noroozi, Zahra Sadat Razavi, Arian Karimi Rouzbahani, Hamidreza Zalpoor, Mohamad Mahjoor

“…This includes investigating tailored hydrogels, hybrid systems, computational modeling, and the integration of gene therapy and immunotherapy techniques. The study also addresses the need for enhanced synthesis techniques, stability, scalability, and cost-cutting measures to overcome obstacles and advance the clinical use of hydrogel-based nanoparticles in treating brain tumors. …”
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Coping strategies of fathers and siblings of children with cancer: a literature review by Teresa Rea, Vincenza Sansone, Andrea Zibaldo, Anna Bellingrath, Assunta Guillari

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PET imaging of AAV9 and AAVBR1 trafficking in normal mice by Aditya Bansal, Shalini Sharma, Manasa Kethamreddy, Mukesh K. Pandey

“…Abstract Adeno-associated virus (AAV) mediated gene therapy is advancing and needs a noninvasive imaging tool to evaluate its effective targeting, biodistribution and clearance for precise use in humans. …”
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