The Diagnosis and Treatment of Branch Retinal Vein Occlusions: An Update by Diana-Maria Darabuş, Rodica Georgiana Dărăbuş, Mihnea Munteanu

Subjects: Get full text

Rhesus Cytomegalovirus-encoded Fcγ-binding glycoproteins facilitate viral evasion from IgG-mediated humoral immunity by Claire E. Otero, Sophia Petkova, Martin Ebermann, Husam Taher, Nessy John, Katja Hoffmann, Angel Davalos, Matilda J. Moström, Roxanne M. Gilbride, Courtney R. Papen, Aaron Barber-Axthelm, Elizabeth A. Scheef, Richard Barfield, Lesli M. Sprehe, Savannah Kendall, Tabitha D. Manuel, Teresa Beechwood, Linh Khanh Nguyen, Nathan H. Vande Burgt, Cliburn Chan, Michael Denton, Zachary J. Streblow, Daniel N. Streblow, Alice F. Tarantal, Scott G. Hansen, Amitinder Kaur, Sallie Permar, Klaus Früh, Hartmut Hengel, Daniel Malouli, Philipp Kolb

Get full text

HLA-G Expression on Blasts and Tolerogenic Cells in Patients Affected by Acute Myeloid Leukemia by Grazia Locafaro, Giada Amodio, Daniela Tomasoni, Cristina Tresoldi, Fabio Ciceri, Silvia Gregori

Get full text

Transient lymphocyte count decrease correlates with oncolytic adenovirus efficacy in humans: mechanistic and biomarker findings from TUNIMO phase I trial by Tuomo Alanko, Akseli Hemminki, Víctor Cervera-Carrascón, Riikka Havunen, Kristian Taipale, Dafne C A Quixabeira, Jorma Sormunen, Katriina Peltola, Suvi Sorsa, Santeri A Pakola, Elise Jirovec, Lyna Haybout, Claudia Kistler, Tatiana V Kudling, Victor Arias, James H A Clubb, Mirte van der Heijden, Teijo Pellinen, Joao M Santos

Get full text

Mouse Umbilical Cord Mesenchymal Stem Cell Paracrine Alleviates Renal Fibrosis in Diabetic Nephropathy by Reducing Myofibroblast Transdifferentiation and Cell Proliferation and Upr... by Hongde Li, Pengfei Rong, Xiaoqian Ma, Wei Nie, Yan Chen, Juan Zhang, Qiong Dong, Min Yang, Wei Wang

Get full text

Pirfenidone Accelerates Wound Healing in Chronic Diabetic Foot Ulcers: A Randomized, Double-Blind Controlled Trial by Luz E. Gasca-Lozano, Silvia Lucano-Landeros, Héctor Ruiz-Mercado, Adriana Salazar-Montes, Ana Sandoval-Rodríguez, Jesus Garcia-Bañuelos, Arturo Santos-Garcia, Judith R. Davila-Rodriguez, José Navarro-Partida, Hiram Bojórquez-Sepúlveda, Juan Castañeda-Gomez, José Domínguez-Rosales, Myriam A. Ruiz-Arcos, María Guadalupe Sánchez-Parada, Juan Armendariz-Borunda

Get full text

Unwanted disorders and xenogeneic graft‐versus‐host disease in experimental immunodeficient mice: How to evaluate and how to report by Seyed Mostafa Monzavi, Samad Muhammadnejad, Vahid Mansouri, Hami Ashraf, Naser Ahmadbeigi

Get full text

Retinoic Acid Signal Negatively Regulates Osteo/Odontogenic Differentiation of Dental Pulp Stem Cells by Jiangyi Wang, Guoqing Li, Lei Hu, Fei Yan, Bin Zhao, Xiaoshan Wu, Chunmei Zhang, Jinsong Wang, Juan Du, Songlin Wang

Get full text

Linking Neuroinflammation and Neurodegeneration in Parkinson’s Disease by Géraldine Gelders, Veerle Baekelandt, Anke Van der Perren

Get full text

The oncolytic adenovirus TILT-123 with pembrolizumab in platinum resistant or refractory ovarian cancer: the phase 1a PROTA trial by Matthew Stephen Block, James Hugo Armstrong Clubb, Johanna Mäenpää, Santeri Pakola, Dafne Carolina Alves Quixabeira, Tatiana Kudling, Elise Jirovec, Lyna Haybout, Mirte van der Heijden, Sanae Zahraoui, Susanna Grönberg-Vähä-Koskela, Sini Raatikainen, Victor Arias, Saru Basnet, Nea Ojala, Teijo Pellinen, Annabrita Hemmes, Katja Välimäki, Annukka Pasanen, Tuomo Alanko, Daniel Adamo, Susan Ramadan, Jorma Sormunen, Juha Kononen, Julia Wanda Cohen, Michael Jon Chisamore, John Goldfinch, Suvi Sorsa, Riikka Havunen, Claudia Kistler, Aino Kalervo, Víctor Cervera-Carrascon, João Manuel dos Santos, Akseli Hemminki

Get full text

Understanding and Prevention of “Therapy-” Induced Dyskinesias by Iciar Aviles-Olmos, Zinovia Kefalopoulou, Thomas Foltynie

“…In this paper we discuss the details of what is understood regarding the development of dyskinesias with relevance to cell and gene therapy and potential strategies to minimize their occurrence.…”
Get full text

Specific types of male infertility are correlated with T cell exhaustion or senescence signatures by Giada Amodio, Giorgia Giacomini, Luca Boeri, Massimiliano Raffo, Simone Cilio, Edoardo Pozzi, Federico Belladelli, Fausto Negri, Anna Maria Ferrara, Alessia d’Arma, Francesca Romana Santoni de Sio, Luca Pagliardini, Enrico Papaleo, Eugenio Ventimiglia, Massimo Alfano, Francesco Montorsi, Andrea Salonia, Silvia Gregori

Get full text

Optimization Manufacture of Virus- and Tumor-Specific T Cells by Natalia Lapteva, Juan F. Vera

Get full text

Maximizing the Survival of Amyotrophic Lateral Sclerosis Patients: Current Perspectives by Osama A. Khairoalsindi, Ahmad R. Abuzinadah

“…The recent data on masitinib, the role of enteral feeding, gene therapy, and stem cell therapy is discussed.…”
Get full text

Gene Expression Profiling in Lungs of Chronic Asthmatic Mice Treated with Galectin-3: Downregulation of Inflammatory and Regulatory Genes by Esther López, M. Paz Zafra, Beatriz Sastre, Cristina Gámez, Carlos Lahoz, Victoria del Pozo

“…In a previous study, we demonstrated that treatment of chronic asthmatic mice with gene therapy using plasmid encoding galectin-3 (Gal-3) led to an improvement in Th2 allergic inflammation. …”
Get full text

Colorectal Polyposis and Immune-Based Therapies by Pearl Jacobson-Brown, Manuela G Neuman

“…A broad spectrum of new treatments, including innovative molecular therapies such as gene therapy and treatment with cytokines, is under experimental and preclinical investigation. …”
Get full text

Rapid Heterotrophic Ossification with Cryopreserved Poly(ethylene glycol-) Microencapsulated BMP2-Expressing MSCs by Jennifer Mumaw, Erin T. Jordan, Corinne Sonnet, Ronke M. Olabisi, Elizabeth A. Olmsted-Davis, Alan R. Davis, John F. Peroni, Jennifer L. West, Franklin West, Yangqing Lu, Steven L. Stice

Get full text

Research Status of Clustered Regulary Interspaced Short Palindromic Repeats Technology in the Treatment of Human Papillomavirus (HPV) Infection Related Diseases by Minxue Tang MD

“…This approach offers a refined methodology for the rapid detection of viral infections and provides a robust platform for the safe and effective treatment of diseases associated with viral infections through gene therapy. Purpose: Gene therapy, within this context, involves the strategic delivery of genetic material into target cells via a vector. …”
Get full text

Ex vivo delivery of recombinant IL-10 to human donor lungs by Jonathan C. Yeung, Terumoto Koike, Dirk Wagnetz, Tiago N. Machuca, Riccardo Bonato, Mingyao Liu, Stephen Juvet, Marcelo Cypel, Shaf Keshavjee

“…However, the very short half-life of IL-10 in vivo (∼2 hours) has necessitated the use of gene therapy in almost all animal models of lung transplantation. …”
Get full text

Intramuscular Injection of Adenoassociated Virus Encoding Human Neurotrophic Factor 3 and Exercise Intervention Contribute to Reduce Spasms after Spinal Cord Injury by Yu-Xin Chang, Yan Zhao, Su Pan, Zhi-Ping Qi, Wei-Jian Kong, Yi-Ran Pan, Hong-Ru Li, Xiao-Yu Yang

“…Our study shows that the combination of AAV-NT3 gene therapy and exercise can alleviate muscle spasm after spinal cord injury by altering the excitability of spinal interneurons and motor neurons. …”
Get full text