Metabolic Alteration in Hepatocellular Carcinoma: Mechanism of Lipid Accumulation in Well-Differentiated Hepatocellular Carcinoma by Hideo Suzuki, Motoyuki Kohjima, Masatake Tanaka, Takeshi Goya, Shinji Itoh, Tomoharu Yoshizumi, Masaki Mori, Mariko Tsuda, Motoi Takahashi, Miho Kurokawa, Koji Imoto, Shigeki Tashiro, Akifumi Kuwano, Masaki Kato, Seiji Okada, Makoto Nakamuta, Yoshihiro Ogawa

“…Besides, the metabolomics was evaluated and integrated to gene expressions in nonalcoholic steatohepatitis (NASH)-HCC model mice. …”
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Podocyte-related biomarkers' role in evaluating renal toxic effects of silver nanoparticles with the possible ameliorative role of resveratrol in adult male albino rats by Eman El-Sayed Khayal, Mona G. Elhadidy, Sulaiman Mohammed Alnasser, Manal Mohammad Morsy, Azza I. Farag, Samah A. El-Nagdy

“…Upregulation of interleukin 1 beta, tumor necrosis factor-alpha, and monocyte chemoattractant protein-1 gene expressions with downregulation of nephrin and podocin gene expressions in renal tissues were also observed. …”
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The prognostic and immunomodulatory role of the MMR system in patients with stomach adenocarcinoma by Zhihui Tian, Lili Yang, Rong Yang, Wenhui Yang

“…GEPIA2 was used to explore the association of MMR genes expression with clinical stage and overall survival. …”
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Guttate hypopigmentation in Darier disease: A rare presentation by Aradhana Rout, Ashish Kumar Pandey, Karthi Kishore

“…Due to variable gene expressivity, the clinical manifestations are often atypical and of varied severity. …”
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What is known and unknown about the role of neuroendocrine genes Ptprn and Ptprn2 by Stanko S. Stojilkovic, Srdjan J. Sokanovic, Stephanie Constantin

“…The protein tyrosine phosphatase receptors N and N2 are encoded by the Ptprn and Ptprn2 genes expressed in neuroendocrine cells of the hypothalamus, pituitary gland, and diffuse neuroendocrine system, including the pancreas, lung, and intestine. …”
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Drought Adaptation and Responses of Stipa krylovii Vary Among Different Regions: Evidence From Growth, Physiology, and RNA‐Seq Transcriptome Analysis by Ziqing Gong, Zehang Qu, Yulin Liu, Tao Wang, Baijie Fan, Anzhi Ren, Yubao Gao, Nianxi Zhao

“…By Kyoto Encyclopedia of Genes and Genomes (KEGG) functional enrichment analysis on gene expressions of individuals from each treatment, unique enriched pathways were found under heavy drought. (2) The decrease in the number of tillers with the increasing drought was much lower for individuals from the western region than those from the other two regions. …”
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Decompensation of β-Cells in Diabetes: When Pancreatic β-Cells Are on ICE(R) by Roberto Salvi, Amar Abderrahmani

“…The seminal function of ICER is to negatively regulate the production and secretion of insulin by repressing the genes expression. This is part of adaptive response required for proper β-cells function in response to environmental factors. …”
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Rozwój genetyki i nauk żywieniowych a działania na rzecz zachowania zdrowia by Grażyna Nowicka

“…On the other hand nutrients can significantly influence different genes expression and metabolic processes. Knowledge of genetic susceptibility to disease will help identify people at enhance risk and their response to diet. …”
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Extrinsic and Intrinsic Regulation of Axon Regeneration by MicroRNAs after Spinal Cord Injury by Ping Li, Zhao-Qian Teng, Chang-Mei Liu

“…MicroRNAs can modulate multiple genes’ expression and are tightly controlled during nerve development or the injury process. …”
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Transcriptome and DNA Methylome Dynamics during Triclosan-Induced Cardiomyocyte Differentiation Toxicity by Guizhen Du, Mingming Yu, Lingling Wang, Weiyue Hu, Ling Song, Chuncheng Lu, Xinru Wang

“…Our findings indicate that TCS exposure might cause cardiomyocyte differentiation toxicity and provide the new insights into how environmental factors regulate DNA methylation and gene expressions during heart development.…”
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Potential Involvement of Type I Interferon Signaling in Immunotherapy in Seasonal Allergic Rhinitis by Lina Mattson, Antonio Lentini, Danuta R. Gawel, Tejaswi V. S. Badam, Mikael Benson, Torbjorn Ledin, Colm E. Nestor, Mika Gustafsson, Jordi Serra-Musach, Janne Bjorkander, Zou Xiang, Huan Zhang

“…As interferon signaling involves multiple genes, expression profiling studies were performed, showing altered expression of the pathway. …”
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Traditional pediatric massage enhanced the skeletal muscle mass in OVA-exposed adolescent rats via regulating SCFAs-FFAR2-IGF-1/AKT pathway by Lin Lin, Siyuan Li, Que Liu, Xingxing Zhang, Ying Xiong, Shaoyun Zhao, Liyue Cao, Jiaxuan Gong, Yaping Liu, Rong Wu

“…The protein and gene expressions of free fatty acid receptor 2 in SM were detected by using immunohistochemical staining and qRT-PCR, respectively. qRT-PCR was used to detect other relative gene expressions that were closely related with SM mass. …”
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Folic Acid: Sources, Chemistry, Absorption, Metabolism, Beneficial Effects on Poultry Performance and Health by Herinda Pertiwi, Mohamad Yusril Nur Mahendra, Juriah Kamaludeen

“…At the same time, the effect on poultry health influences antioxidant activities, thyroid hormones, blood biochemicals, anti-inflammatory gene expressions, and immune responses. The present review deals with FA sources, chemistry, absorption, metabolism, effects on performance, and poultry health, which are based on valid basic information.…”
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Ammonia-Assimilating Bacteria Promote Wheat (<i>Triticum aestivum</i>) Growth and Nitrogen Utilization by Yuqian Gao, Qi Zhang, Yuannan Chen, Yanqing Yang, Chenxiao Zhou, Jiayang Yu, Yanan Li, Liyou Qiu

“…However, root GS, GOGAT enzyme activities, and ammonia assimilation-related gene expressions were lower than the controls. The results suggest that the ammonia-assimilating bacterium promotes wheat growth, nitrogen accumulation, and soil nitrogen immobilization by establishing an ammonia and amino acid exchange with roots and enhancing root antioxidant capacity, making it a potential plant growth-promoting rhizobacteria (PGPR).…”
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Endothelial SHANK3 regulates tight junctions in the neonatal mouse blood-brain barrier through β-Catenin signaling by Yong-Eun Kim, Minseong Kim, Sunwhi Kim, Raham Lee, Yusuke Ujihara, Esther Magdalena Marquez-Wilkins, Yong-Hui Jiang, Esther Yang, Hyun Kim, Changhoon Lee, Changwon Park, Il Hwan Kim

“…Here we report that SHANK3, an ASD-risk gene, expresses in the BBB-forming brain endothelial cells (BECs) and regulates tight junctional (TJ) integrity essential for BBB’s barrier function. …”
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The regulatory roles of RNA-binding proteins in the tumour immune microenvironment of gastrointestinal malignancies by Dongqi Li, Xiangyu Chu, Weikang Liu, Yongsu Ma, Xiaodong Tian, Yinmo Yang

“…This review summarizes current advances in exploring the roles of RBPs in regulating genes expression and their effect on the TIME of GI tumours, then providing theoretical insights for RBP-targeted cancer therapies.…”
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Exploring novel immunotherapy biomarker candidates induced by cancer deformation. by Se Min Kim, Namu Park, Hye Bin Park, JuKyung Lee, Changho Chun, Kyung Hoon Kim, Jong Seob Choi, Hyung Jin Kim, Sekyu Choi, Jung Hyun Lee

“…To achieve this, the study places a strong emphasis on investigating Ig genes, a characteristic of immune checkpoint inhibitors, particularly genes expressing Ig-like domains with altered expression levels induced by "cancer deformation," a condition associated with cancer malignancy. …”
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Effect of yellow rice wine on anti-aging ability in aged mice induced by d-galactose by Rong Liu, Zukang Fu, Fengjie Zhang, Qingzhong Mao, Chunguang Luan, Xinglin Han, Jie Xue, Deliang Wang, Si Qin, Feike Hao

“…Besides, results from the Morris water maze test suggested that YRW significantly reversed cognitive impairment and also alleviated neuroapoptosis in the experimental mice by regulating the gene expressions of Bax/Bcl-2 and caspase-3. The above results indicated YRW has a potential anti-aging effect in mice and provided us certain molecular evidence for this action.…”
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The widely used Ucp1-Cre transgene elicits complex developmental and metabolic phenotypes by Manasi Suchit Halurkar, Oto Inoue, Archana Singh, Rajib Mukherjee, Meghana Ginugu, Christopher Ahn, Christian Louis Bonatto Paese, Molly Duszynski, Samantha A. Brugmann, Hee-Woong Lim, Joan Sanchez-Gurmaches

“…Mapping the transgene insertion site reveals insertion in chromosome 1 accompanied by large genomic alterations disrupting several genes expressed in a range of tissues. Notably, Ucp1-Cre Evdr transgene retains an extra Ucp1 gene copy that may be highly expressed under high thermogenic burden. …”
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Possibility of the Use of Public Microarray Database for Identifying Significant Genes Associated with Oral Squamous Cell Carcinoma by Ki-Yeol Kim, In-Ho Cha

“…There were different expression scales between the two datasets, even though these datasets were generated under the same platforms - Affymetrix U133A gene chips. We discretized gene expressions of the two datasets by adjusting the differences between the datasets for detecting the more reliable information. …”
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