Downregulation of RIPK4 Expression Inhibits Epithelial-Mesenchymal Transition in Ovarian Cancer through IL-6 by Huan Yi, Yan-zhao Su, Rong Lin, Xiang-qin Zheng, Diling Pan, Dan-mei Lin, Xiang Gao, Rong Zhang

“…RIPK4 has been implicated in multiple cancer types, but its role in ovarian cancer (OC) has not been clearly elucidated. Our data from Gene Expression Profiling Interactive Analysis, RT-PCR, and immunohistochemical analysis showed that RIPK4 was expressed at higher levels in OC tissues and cells than in normal ovarian tissues and cells. …”
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Integrated analysis of M2 macrophage-related gene prognostic model and single-cell sequence to predict immunotherapy response in lung adenocarcinoma by Meifang Li, Zhiping Wang, Bin Huang, Yanyun Lai, Meng Zhang, Cheng Lin

“…We aimed to construct a prognostic signature to predict the immunotherapy efficacy and prognosis in LUAD.MethodsGSE26939 and GSE19188 chips were downloaded from the Gene Expression Omnibus (GEO). Weighted gene co-expression network analysis (WGCNA) and least absolute shrinkage and selection operator (LASSO) analysis were used to screen M2 macrophage-related prognostic genes. …”
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Potential Biomarkers for Predicting the Risk of Developing Into Long COVID After COVID‐19 Infection by Zhiyong Hou, Yu Ming, Jun Liu, Zhong Wang

“…Methods Transcriptomic data sets of those within gene expression profiles of COVID‐19, long COVID, and healthy controls were retrieved from the GEO database. …”
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Tissue-specific roles of de novo DNA methyltransferases by Dániel Márton Tóth, Flóra Szeri, Mária Ashaber, Muhyiddeen Muazu, Lóránt Székvölgyi, Tamás Arányi

“…Abstract DNA methylation, catalyzed by DNA methyltransferases (DNMT), plays pivotal role in regulating embryonic development, gene expression, adaption to environmental stress, and maintaining genome integrity. …”
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Exploring microRNA-Mediated Immune Responses to Soil-Transmitted Helminth and Herpes Simplex Virus Type 2 Co-Infections by Roxanne Pillay, Pragalathan Naidoo, Zilungile L. Mkhize-Kwitshana

“…MiRNAs are a class of short, single-stranded, non-coding RNAs that regulate gene expression post-transcriptionally. Thereby, miRNAs regulate various essential biological processes including immunity. …”
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Comprehensive analysis of disulfidptosis-related genes and the immune microenvironment in heart failure by Linna Zhao, Juanjuan Zhang, Juanjuan Zhang, Qiuhang Song, Cheng Dai, Yiping Qin, Aiying Li, Aiying Li

“…Moreover, our analysis identified two distinct clusters of DRGs and these clusters exhibited differences in terms of immune cell abundance, immune response, and HLA gene expression. The biological functions associated with these differences were also revealed.ConclusionOur discovery underscores the pivotal role of DRGs in shaping the diversity and intricacy of the immune microenvironment in HF.…”
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Potential involvement of cuproptosis induced by m6A-modified autophagy gene ATG10 in KICH by Qingyun Zhu, Daiquan Fu, Zhaohui Zhu, Jian Wu, Chenxi Li, Jiajun Chen, Chuan Chen, Yanxiang Li, Yuehui Guo, Xiangqi Li

“…This study employed gene expression analysis, immunohistochemistry (IHC), Spearman’s correlation, immune cell infiltration assessment, and molecular network construction to investigate the autophagy gene ATG10 in KICH. …”
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RBM47 is a novel immunotherapeutic target and prognostic biomarker in gliomas by Wei Wei, Yongfu Cao, Xin Lu, Long Wang, Jianbin Li, Guojun Deng, Donghai Li, Limin Xiao

“…Therefore, a comprehensive investigation into the immunomodulatory roles of RBM47 in gliomas was conducted, leveraging gene expression data from multi-omic datasets. The prognosis of patients with gliomas considering RBM47 was elucidated using bioinformatics methods and clinical data, with results validated using immunohistochemistry and immunofluorescence analyses. …”
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MicroRNA-223 Expression Is Upregulated in Insulin Resistant Human Adipose Tissue by Tung-Yueh Chuang, Hsiao-Li Wu, Chen-Chun Chen, Gloria Mabel Gamboa, Lawrence C. Layman, Michael P. Diamond, Ricardo Azziz, Yen-Hao Chen

“…MicroRNAs (miRNAs) are short noncoding RNAs involved in posttranscriptional regulation of gene expression and influence many cellular functions including glucose and lipid metabolism. …”
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Bioinformatics analysis combined with experimental validation reveals the biological role of the ILK gene in prostate cancer by Xiao-xiang Yu, Yi Liu, Rong-jiang Luo, Zi-xuan Song, Wen-kai Chen, Zeng-mi Mo, Feng-jing Wang

“…Methods To identify key genes in PCa, we utilized differential gene expression analysis and Weighted Gene Co-expression Network Analysis (WGCNA). …”
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Assessment of different enrichment methods revealed the optimal approach to identify bovine circRnas by Yixin Wang, Jian Wang, Robert J. Gruninger, Tim A. McAllister, Mingzhou Li, Le Luo Guan

“…Although circular RNAs (circRNAs) play important roles in regulating gene expression, the understanding of circRNAs in livestock animals is scarce due to the significant challenge to characterize them from a biological sample. …”
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Genome-Wide Identification and Expression Profiling of the <i>SPL</i> Transcription Factor Family in Response to Abiotic Stress in Centipedegrass by Dandan Kong, Maotao Xu, Siyu Liu, Tianqi Liu, Boyang Liu, Xiaoyun Wang, Zhixiao Dong, Xiao Ma, Junming Zhao, Xiong Lei

“…SQUAMOSA promoter-binding protein-like (SPL) transcription factors play a critical role in the regulation of gene expression and are indispensable in orchestrating plant growth and development while also improving resistance to environmental stressors. …”
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High Expression of Ten Eleven Translocation 1 Is Associated with Poor Prognosis in Hepatocellular Carcinoma by Haopeng Wen, Tengfei Ji, Liteng Lin, Nan Cheng, Kangshun Zhu, Liangqi Cao

“…Four independent datasets with gene expression data and clinical data of HCC samples were downloaded from public databases. …”
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Endothelial Differentiation of Human Adipose-Derived Stem Cells on Polyglycolic Acid/Polylactic Acid Mesh by Meng Deng, Yunpeng Gu, Zhenjun Liu, Yue Qi, Gui E. Ma, Ning Kang

“…Cell adhesion, viability, and distribution of hADSCs on PGA/PLA mesh were observed by CM-Dil labeling, live/dead staining, and SEM examination while endothelial differentiation was evaluated by flow cytometry, Ac-LDL/UEA-1 uptake assay, immunofluorescence stainings, and gene expression analysis of endothelial related markers. …”
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The Kat in the HAT: The Histone Acetyl Transferase Kat6b (MYST4) Is Downregulated in Murine Macrophages in Response to LPS by Smita Shukla, Carly Levine, Roopa Payanur Sripathi, Genie Elson, Carol Susan Lutz, Samuel Joseph Leibovich

“…As Kat6B is a HAT that has the potential to modulate gene expression by its effects on chromatin accessibility, we are continuing our studies into the potential roles of this epigenetic modulator in macrophage activation pathways.…”
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Chronic Ethanol Feeding Modulates Inflammatory Mediators, Activation of Nuclear Factor-κB, and Responsiveness to Endotoxin in Murine Kupffer Cells and Circulating Leukocytes by Miriam Maraslioglu, Elsie Oppermann, Carolin Blattner, Roxane Weber, Dirk Henrich, Christian Jobin, Elke Schleucher, Ingo Marzi, Mark Lehnert

“…Furthermore, LPS and TNF-α stimulated the gene expression of different inflammatory mediators, in part, in a NF-κB-dependent manner.…”
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Anxiety-like behavior and altered hippocampal activity in a transgenic mouse model of Fabry disease by Kai Kummer, Jeiny Luna Choconta, Marie-Luise Edenhofer, Archana Bajpai, Gopuraja Dharmalingam, Theodora Kalpachidou, David A. Collier, Michaela Kress

“…Hippocampus single-cell sequencing further revealed that Gb3 accumulation was associated with differential gene expression in neuronal and non-neuronal cell populations with granule, excitatory and interneurons, as well as microglia and endothelial cells as the main clusters with the most dysregulated genes. …”
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Evaluation of Epstein-Barr Virus Latent Membrane Protein 2 Specific T-Cell Receptors Driven by T-Cell Specific Promoters Using Lentiviral Vector by Dongchang Yang, Qing Shao, Hua Sun, Xiaoxin Mu, Yun Gao, Runqiu Jiang, Jiajie Hou, Kun Yao, Yun Chen, Beicheng Sun

“…We compared TCR-specific promoters of distinct origin in lentiviral vectors, that is, Vβ6.7, delta, luria, and Vβ5.1 to evaluate TCR gene expression in human primary peripheral blood monocytes and T cell line HSB2. …”
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MicroRNAs obtained from cervical swabs in predicting preterm birth by Rosalia Purbandari, Suheni Ninik Hariyati

“…ABSTRACT Objective: Identifying the risk of preterm birth is crucial for early intervention. miRNAs, small noncoding RNAs that regulate gene expression, play a key role in development and tissue maintenance. …”
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The Critical Role of YAP/BMP/ID1 Axis on Simulated Microgravity‐Induced Neural Tube Defects in Human Brain Organoids by Di Guo, Bin Yao, Wen‐Wei Shao, Jia‐Chen Zuo, Zhe‐Han Chang, Jian‐Xin Shi, Nan Hu, Shuang‐Qing Bao, Meng‐Meng Chen, Xiu Fan, Xiao‐Hong Li

“…SMG impairs N‐cadherin‐based adherens junction formation, leading to neural tube defects associated with dysregulated self‐renewal capacity and neuroepithelial disorganization in human brain organoids. Bulk gene expression analyses reveal that SMG alters Hippo and BMP signaling in brain organoids. …”
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