Exploring the utility of snRNA-seq in profiling human bladder tissue: A comprehensive comparison with scRNA-seq by Briana Santo, Emily E. Fink, Alexandra E. Krylova, Yi-Chia Lin, Mohamed Eltemamy, Alvin Wee, Oliver Wessely, Byron H. Lee, Angela H. Ting

“…Summary: Single cell sequencing technologies have revolutionized our understanding of biology by mapping cell diversity and gene expression in healthy and diseased tissues. While single-cell RNA sequencing (scRNA-seq) has been widely used, interest in single-nucleus RNA sequencing (snRNA-seq) is growing due to its benefits, including the ability to analyze archival tissues and capture rare cell types that are challenging to dissociate. …”
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Evolutionary analysis of the DHHCs in Saccharinae by Hao Wen, Xinyu Liu, Xueting Zhao, Tingting Zhao, Cuilian Feng, Hailong Chang, Jungang Wang, Jishan Lin

“…Ka/Ks ratio analysis indicated that gene duplication in these species was primarily driven by whole-genome duplication (WGD) and dispersed duplication (DSD), with DHHC genes evolving under strong purifying selection. Gene expression and trait correlation analysis revealed a significant negative correlation between SspDHHC28A expression in S. spontaneum and sucrose content, suggesting a role in photosynthesis product transport during rapid growth. …”
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Ya That Somdun improves hepatic steatosis in hyperlipidemic rats by Suchittra Samuhasaneeto, Gorawit Yusakul, Chuchard Punsawad, Kingkan Bunluepuech

“…Serum lipid profiles, body weights, liver and renal functional markers, gene expression involved in lipid metabolism, and liver histopathology were examined. …”
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Lactylation modulation identifies key biomarkers and therapeutic targets in KMT2A-rearranged AML by Dan Liu, Silu Liu, Yujie Ji, Ziyan Jin, Zhewei He, Mengjia Hou, Dongyang Li, Xiao Ma

“…This research examined the influence of lactylation on gene expression within KMT2Ar-AML, initially identifying twelve notable lactylation-dependent differentially expressed genes (DEGs). …”
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Butyrate Supplementation Improves Intestinal Health and Growth Performance in Livestock: A Review by Wenting Chen, Qingshan Ma, Yan Li, Lin Wei, Zhenwei Zhang, Adnan Khan, Muhammad Zahoor Khan, Changfa Wang

“…Additionally, butyrate plays a role in the epigenetic regulation of gene expression through histone acetylation, influencing tissue development and immune modulation. …”
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Prediction of miRNA-circRNA Associations Based on k-NN Multi-Label with Random Walk Restart on a Heterogeneous Network by Zengqiang Fang, Xiujuan Lei

“…Circular RNAs (circRNAs) play important roles in various biological processes, as essential non-coding RNAs that have effects on transcriptional and posttranscriptional gene expression regulation. Recently, many studies have shown that circRNAs can be regarded as micro RNA (miRNA) sponges, which are known to be associated with certain diseases. …”
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Deciphering sepsis: transforming diagnosis and treatment through systems immunology by Robert E. W. Hancock, Andy An, Claudia C. dos Santos, Amy H. Y. Lee

“…Immune dysfunctions evident very early in sepsis drive the development of novel diagnostic gene expression signatures (e.g., cellular reprogramming) that could inform early therapy. …”
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A cell atlas of the human fallopian tube throughout the menstrual cycle and menopause by Melanie Weigert, Yan Li, Lisha Zhu, Heather Eckart, Preety Bajwa, Rahul Krishnan, Sarah Ackroyd, Ricardo Lastra, Agnes Bilecz, Anindita Basu, Ernst Lengyel, Mengjie Chen

“…Our scRNA-seq comparison of 85,107 pre- and 46,111 post-menopausal fallopian tube cells reveals substantial shifts in cell type frequencies, gene expression, transcription factor activity, and cell-to-cell communications during menopause and menstrual cycle. …”
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Liraglutide Promotes Osteoblastic Differentiation in MC3T3-E1 Cells by ERK5 Pathway by Yue Sun, Yuzhen Liang, Zhengming Li, Ning Xia

“…The expression levels of the ERK5 signaling pathway key proteins (MEK5, p-ERK5, ERK5, and NUR77) were increased following liraglutide treatment in MC3T3-E1 cells, and the gene expression levels of the ERK5 signaling pathway were also elevated. …”
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Anti-Inflammatory Effects of Aster incisus through the Inhibition of NF-κB, MAPK, and Akt Pathways in LPS-Stimulated RAW 264.7 Macrophages by Daniel Ngabire, Yeong-Ae Seong, Maheshkumar Prakash Patil, Irvine Niyonizigiye, Yong Bae Seo, Gun-Do Kim

“…Aster incisus also reduced significantly the production of inflammation-related enzymes (iNOS, Cox-2) and cytokines (TNFα, IL-1β, and IL-6) and the gene expression of the proinflammatory cytokines. Additionally, further Western blot results indicated that Aster incisus inhibited the expression of p-PI3K, p-IκBα, p-p65 NF-κB, p-ERK1/2, p-SAPK/JNK, and p-Akt. …”
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Pengaruh Pemberian Mesenchymal Stem Cells Wharton's Jelly terhadap Ekspresi Gen Sirtuin 1 pada Tikus Model Alzheimer by Havina Nurul Aizah, Amel Yanis, Hirowati Ali, Tofrizal Tofrizal, Cimi Ilmiawati, Dessy Arisanty

“…Conclusion: There was an increased Sirtuin 1 gene expression in Alzheimer’s rat Model after being given Mesenchymal Stem Cells Wharton’s Jelly. …”
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Identification of retinol dehydrogenase 10 as a shared biomarker for metabolic dysfunction-associated steatotic liver disease and type 2 diabetes mellitus by Fangyu Li, Rui Li, Hongjun Deng

“…Finally, we used RT-qPCR, immunofluorescence, Western blotting and Elisa to validate hub gene expression in MASLD and T2DM mouse models.ResultsThis analysis identified 20 genes shared by MASLD and T2DM that were enriched in the bile secretion, phototransduction, cancer, carbohydrate digestion and absorption, cholesterol/glycerol metabolism, and retinol metabolism. …”
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Protective effect of Panax ginseng extract on cisplatin-induced AKI via downregulating cell death associated genes by Reza Alipanah-Moghadam, Vahideh Aghamohammadi, Sina Seifi, Hedieh Esmaeili, Somaieh Noroozzadeh, Farhad Jeddi, Ramin Salimnejad, Ali Nemati

“…Our findings displayed amelioration of cisplatin-induced AKI and dose-dependent decrease of the NF-κB gene expression and cell death-inducing genes by administration of P. ginseng extract.…”
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Progressive Intramuscular Haematoma in a 12-Year-Old Boy: A Case of Acquired Haemophilia A by Manori Gamage, Sadeepa Weerasinghe, Mohamed Nasoor, A. M. P. W. Karunarathne, Sashi Praba Abeyrathne

“…He had prolonged APPTT level with very high antibody titer against factor VIII. His gene expression for factor VIII was found to be normal. …”
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The FvABF3-FvALKBH10B-FvSEP3 cascade regulates fruit ripening in strawberry by Renkun Tang, Xiaoyu Duan, Leilei Zhou, Guangtong Gao, Jinying Liu, Yuying Wang, Xingfeng Shao, Guozheng Qin

“…Abstract Fruit ripening is a highly-orchestrated process that requires the fine-tuning and precise control of gene expression, which is mainly governed by phytohormones, epigenetic modifiers, and transcription factors. …”
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In-Depth Global Analysis of Transcript Abundance Levels in Porcine Alveolar Macrophages Following Infection with Porcine Reproductive and Respiratory Syndrome Virus by Laura C. Miller, John D. Neill, Gregory P. Harhay, Kelly M. Lager, William W. Laegreid, Marcus E. Kehrli

“…Serial Analysis of Gene Expression (SAGE) was used to create and survey the transcriptome of in vitro mock-infected and PRRSV strain VR-2332-infected porcine alveolar macrophages (PAM) at 0, 6, 12, 16, and 24 hours after infection. …”
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Age-Related Changes in Female Murine Reproductive Mucosa with respect to γδ T Cell Presence by Katarzyna Skulska, Anna Ewa Kędzierska, Małgorzata Krzyżowska, Grzegorz Chodaczek

“…Interestingly, under the inflammatory state, the lack of γδ T cells in young individuals enhanced MCP-1 production in the vagina and decreased MCP-1 level in the uterus in old females. Our gene expression data point to an antimicrobial role of γδ T lymphocytes. …”
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Anti-Inflammatory and Antioxidant Effects of Aqueous Extract on the Liver and Kidney of PCOS Mice by Samah Hachem MS, Miriam Al Battal MD, Hoda Dakdouk MS, Dania El Natour MD, Jamilah Borjac PhD

“…NLRP3 and its associated genes (caspase-1 and ASC) gene expression was assessed. Results The extract restored normal kidney and liver histology post-PCOS induction. …”
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A high coverage reference transcriptome assembly of pea (<i>Pisum sativum</i> L.) mycorrhizal roots by A. M. Afonin, I. V. Leppyanen, O. A. Kulaeva, O. Y. Shtark, I. A. Tikhonovich, E. A. Dolgikh, V. A. Zhukov

“…Genes specific to mycorrhizal roots were found in the assembly, their expression patterns were examined with qPCR on two pea cultivars, Frisson and Finale. The gene expression depended on the inoculation stage and on the pea cultivar. …”
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Identification of markers correlating with mitochondrial function in myocardial infarction by bioinformatics. by Wenlong Kuang, Jianwu Huang, Yulu Yang, Yuhua Liao, Zihua Zhou, Qian Liu, Hailang Wu

“…<h4>Methods</h4>The datasets (GSE775, GSE183272 and GSE236374) were from National Center for Biotechnology Information (NCBI) Gene Expression Omnibus (GEO) in conjunction with mitochondrial gene data that were downloaded from the MitoCarta 3.0 database. …”
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