Nanoparticle-mediated gene delivery techniques in plant systems by Kuber Shivashakarappa, Sureshbabu Marriboina, Korsi Dumenyo, Ali Taheri, Zeinab Yadegari

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Self-Assembling Multifunctional Peptide Dimers for Gene Delivery Systems by Kitae Ryu, Gyeong Jin Lee, Ji-yeong Choi, Taewan Kim, Tae-il Kim

“…These results show the potential of MPD for MMP-2 targeted gene delivery systems due to its multifunctionality.…”
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Martini compatible coarse-grained model of polyethylenimine for pulmonary gene delivery by Graham Lunt, Niloofar Hashemi, Subhamoy Mahajan, Tian Tang

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Current Progress on MicroRNA-Based Gene Delivery in the Treatment of Osteoporosis and Osteoporotic Fracture by Xi Sun, Qi Guo, Wenhua Wei, Stephen Robertson, Ying Yuan, Xianghang Luo

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One-Step Formation of Chondrocytes through Direct Reprogramming via Polysaccharide-Based Gene Delivery by Qingtong Yu, Yan Wang, Xia Cao, Wenwen Deng, Michael Adu Frimpong, Jiangnan Yu, Ximing Xu

“…These findings indicate that pmPPY could be a promising gene vector for the generation of chondrocytes via single-gene delivery strategy, which might provide abundant chondrocytes for cartilage repair.…”
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Potential for Isolation of Immortalized Hepatocyte Cell Lines by Liver-Directed In Vivo Gene Delivery of Transposons in Mice by Masahiro Sato, Issei Saitoh, Emi Inada, Shingo Nakamura, Satoshi Watanabe

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Fabrication of Core-Shell PEI/pBMP2-PLGA Electrospun Scaffold for Gene Delivery to Periodontal Ligament Stem Cells by Qiao Xie, Lie-ni Jia, Hong-yu Xu, Xiang-gang Hu, Wei Wang, Jun Jia

“…In this study, the bioactive PEI (polyethylenimine)/pBMP2- (bone morphogenetic protein-2 plasmid-) PLGA (poly(D, L-lactic-co-glycolic acid)) core-shell scaffolds were prepared using coaxial electrospinning for a controlled gene delivery to hPDLSCs (human periodontal ligament stem cells). …”
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Current issues with antibody-conjugated lipid nanoparticles by Aayush

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Aβ-Induced Repressor Element 1-Silencing Transcription Factor (REST) Gene Delivery Suppresses Activation of Microglia-Like BV-2 Cells by Tongya Yu, Hui Quan, Yuzhen Xu, Yunxiao Dou, Feihong Wang, Yingying Lin, Xue Qi, Yanxin Zhao, Xueyuan Liu

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iTRAQ-Based Proteomic Analysis of Visual Cycle-Associated Proteins in RPE of rd12 Mice before and after RPE65 Gene Delivery by Qinxiang Zheng, Yueping Ren, Radouil Tzekov, Shanshan Hua, Minghan Li, Jijing Pang, Jia Qu, Wensheng Li

“…To investigate the iTRAQ-based proteomic changes of visual cycle-associated proteins in RPE of rd12 mice before and after RPE65 gene delivery. Mehtods. The right eyes of rd12 mice underwent RPE65 gene delivery by subretinal injection at P14, leaving the left eyes as control. …”
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Dual AAV/IL-10 Plus STAT3 Anti-Inflammatory Gene Delivery Lowers Atherosclerosis in LDLR KO Mice, but without Increased Benefit by Maohua Cao, Junaid A. Khan, Bum-Yong Kang, Jawahar L. Mehta, Paul L. Hermonat

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Nonviral Gene Delivery of Growth and Differentiation Factor 5 to Human Mesenchymal Stem Cells Injected into a 3D Bovine Intervertebral Disc Organ Culture System by Christian Bucher, Amiq Gazdhar, Lorin M. Benneker, Thomas Geiser, Benjamin Gantenbein-Ritter

“…Differentiation of MSCs by nonviral gene delivery of growth and differentiation factor 5 (GDF5) by electroporation mediated gene transfer could be an excellent source for cell transplantation. …”
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From bench to bedside: Developing CRISPR/Cas-based therapy for ocular diseases by Qing Zhao, Linxin Wei, Youxin Chen

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Probing aspects of extracellular vesicle associated AAV allows increased vector yield and insight into its transduction and immune-evasive properties by Ming Cheng, Demitri de la Cruz, Adam V. Crain, Paula Espinoza, Carrie Ng, Zachary C. Elmore, Aravind Asokan, Casey A. Maguire

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Biofunctionalized patterned platform as microarray biochip to supervise delivery and expression of pDNA nanolipoplexes in stem cells via mechanotransduction by Mingkui Shen, Yan Hou, Shihui Xu, Jun Tan, Honggang Zhou, Qi Miao, Wanheng Zhang, Yazhou Chen, Nana Wang, Yongtao Wang

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Vector‐Free Deep Tissue Targeting of DNA/RNA Therapeutics via Single Capacitive Discharge Conductivity‐Clamped Gene Electrotransfer by Jeremy L. Pinyon, Georg vonJonquieres, Stephen L. Mow, Amr Al Abed, Keng‐Yin Lai, Mathumathi Manoharan, Edward N. Crawford, Stanley H. Xue, Sarah Smith‐Moore, Lisa J. Caproni, Sarah Milsom, Matthias Klugmann, Nigel H. Lovell, Gary D. Housley

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Spermine Significantly Increases the Transfection Efficiency of Cationic Polymeric Gene Vectors by Yue Lv, Jiaoqin Xue, Pengfei Cui, Lin Qiu

“…<b>Background/Objectives:</b> Non-viral vectors have gained recognition for their ability to enhance the safety of gene delivery processes. Among these, polyethyleneimine (PEI) stands out as the most widely utilized cationic polymer due to its accessibility. …”
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Application of PEI-Modified Magnetic Nanoparticles as Gene Transfer Vector for the Genetic Modification of Animals by Jinhui Cui, Haixin Cui, Yan Wang, Changjiao Sun, Kui Li, Hongyan Ren, Wei Du

“…The efficiency of gene delivery was affected by the mass ratio of nanoparticle/DNA and the amount of nanoparticle/DNA complexes. …”
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Subthalamic hGAD65 Gene Therapy and Striatum TH Gene Transfer in a Parkinson’s Disease Rat Model by Deyu Zheng, Xiaohua Jiang, Junpeng Zhao, Deyi Duan, Huanying Zhao, Qunyuan Xu

“…This is combined with the ex vivo gene delivery of tyrosine hydroxylase (TH) by fibroblasts injected into the striatum. …”
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Recent Advances on Electroconductive Hydrogels Used in Heart Repair and Regeneration by Xu Yan, Huan Sun, Ping Yang

“…Also, EHs are ideal materials for the preparation of cell culture and induction carriers, engineered scaffolds, and patches, as well as cell and gene delivery carriers, all of which aid in tissue formation. …”
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