Blood biomarker dynamics in people with relapsing multiple sclerosis treated with cladribine tablets: results of the 2-year MAGNIFY-MS study by Heinz Wiendl, Frederik Barkhof, Frederik Barkhof, Xavier Montalban, Anat Achiron, Anat Achiron, Tobias Derfuss, Andrew Chan, Suzanne Hodgkinson, Alexandre Prat, Letizia Leocani, Letizia Leocani, Letizia Leocani, Klaus Schmierer, Klaus Schmierer, Finn Sellebjerg, Finn Sellebjerg, Patrick Vermersch, Hulin Jin, Anita Chudecka, Andreas Kloetgen, Dongdong Lin, Lidia Gardner, Nicola De Stefano

“…Reductions in all NK cell subtypes were observed at M3, CD16lowCD56bright and NKp46 cells reconstituted at M6 and M12 respectively. Changes in genes and pathways associated with innate and adaptive immune response were observed after CladT treatment, along with reductions in pro-inflammatory cytokine-producing B and T cells and increases in anti-inflammatory cytokine-producing T cells. …”
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Integrated microbiome, transcriptome and metabolome insight into the alleviating mechanisms of sheep milk in a DSS-induced colitis mouse model by Wenna Yao, Ruilin Du, Shuo Yan, Teligun Bao, Huimin Zhang, Fang Yang, Yue Xue, Yulong Zhao, Siqin Bao, Xihe Li, Yongli Song

“…Transcriptome analysis demonstrated that the expression of genes related to the IL-17 signaling and PI3K-Akt signaling pathways, such as S100A8, S100A9, LNC2, CXCL3, CREB313, CREB314 and CHRM1 were downregulated in the SM group compared to the DSS group. …”
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Exometabolomic exploration of culturable airborne microorganisms from an urban atmosphere by R. Jin, W. Hu, W. Hu, P. Duan, M. Sheng, D. Liu, Z. Huang, M. Niu, L. Wu, J. Deng, P. Fu, P. Fu

“…Annotation through the Kyoto Encyclopedia of Genes and Genomes database helped identify metabolic processes. …”
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Sex disparity in the association between alcohol consumption and sarcopenia: a population-based study by Longbao Yang, Longbao Yang, Qiuju Ran, Qiuju Ran, Yee Hui Yeo, Zhang Wen, Zhang Wen, Shuyue Tuo, Shuyue Tuo, Yong Li, Yong Li, Jia Yuan, Jia Yuan, Shejiao Dai, Shejiao Dai, Jinhai Wang, Jinhai Wang, Fanpu Ji, Fanpu Ji, Fanpu Ji, Fanpu Ji, Xinxing Tantai, Xinxing Tantai

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Petrogenesis of Intrusive body in Northeast of Joveinan, North of Isfahan, Urumieh- Dokhtar magmatic zone by Shahzad Sherafat, Majid Zeidi, Mahnaz Khodami

“…The primary mantle normalized pattern shows the enrichment of large ion lithophile elements (LILE) and depletion of high field strength elements (HFSE), which is one of the geochemical characteristics of the magma related to the subduction zone (Kuscu and Geneli, 2010). The chondrite-normalized rare earth elements diagrams show a medium enrichment of LREE compared to HREE, a weak negative anomaly of Europium, and a flat pattern of heavy rare earth elements. …”
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