Construction and validation of risk prediction models for renal replacement therapy in patients with acute pancreatitis by Fei Zuo, Lei Zhong, Jie Min, Jinyu Zhang, Longping Yao

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Prenatal exposure to polycyclic aromatic hydrocarbons and blood pressure in the early life of children by Xiaodong Chen, Lingling Dong, Lina Yang, Yan Yang, Liyu Yang, Sijia Han

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Continuously relapsing (for two years) course of diarrheal variant of IBS (<i>Clinical case</i>) by Ye. A. Poluektova, S. Yu. Kuchumova, A. A. Kurbatova, A. A. Sheptulin, O. S. Shifrin, V. T. Ivashkin

“…Antispasmodics of various groups, enzyme and antisecretory agents in this relation were prescribed to him without any noteworthy effect for two years prior to admission to Vasilenko Clinic of internal diseases propedeutics, gastroenterology and hepatology. In the clinic differential diagnosis between organic diseases of gastro-intestinal tract was carried out (erosive-ulcerative lesion of the upper parts of GIT, celiac disease, inflammatory bowel diseases), functional gastro-intestinal disorder, thyroid gland hyperfunction). …”
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Concomitant abdominal organ transplantation alongside lung transplantation: An ISHLT transplant database analysis by Renita Wilson, BS, J. Asher Jenkins, MD, Juan Maria Farina, MD, Blake Langlais, MS, Bashar Aqel, MD, Ashraf Omar, MD, Jonathan D’Cunha, MD, PhD, Pedro Reck dos Santos, MD, PhD

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Autoimmune Hepatitis in Children: The Current State of the Problem by G. V. Volynets, A. I. Khavkin, T. A. Skvortsova, V. V. Matkash

“…., those formulated by the main group of the European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) members.Conclusion. …”
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Comparison of Nasopharyngeal Airway with Endoscopic Respiratory Mask for Hypoxemia in Painless Gastrointestinal Endoscopy in Obese Outpatients: Study Protocol for a Randomized Cont... by Xiang D, Deng L, Zhou R, Zhang X, Tian L, Jiang W, Zhou Y, Chen W, Peng Y

“…Dongmei Xiang,1,&ast; Lei Deng,2,&ast; Rui Zhou,3– 5 Xianjie Zhang,1 Lei Tian,1 Wencai Jiang,1 Yukai Zhou,1 Wenya Chen,1 Yanhua Peng1 1Department of Anesthesiology, the Deyang People’s Hospital, Deyang City, Sichuan Province, 618000, People’s Republic of China; 2Department of Gastroenterology, the Deyang People’s Hospital, Deyang City, Sichuan Province, 618000, People’s Republic of China; 3Department of Anesthesiology and Perioperative Medicine, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, Shanghai, 200434, People’s Republic of China; 4Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, Shanghai, 200434, People’s Republic of China; 5Clinical Research Center for Anesthesiology and Perioperative Medicine, Tongji University, Shanghai, 200434, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yanhua Peng, Department of Anesthesiology, the Deyang People’s Hospital, No. 173 section 1 Mount Taishan North Road Jingyang District, Deyang City, Sichuan Province, People’s Republic of China, Email pyhuaa@163.comIntroduction: Sedatives and anesthetics can modify airway tone and induce respiratory depression, exacerbating the gas exchange impairments associated with obesity. …”
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TMEM45A enhances palbociclib resistance and cellular glycolysis by activating AKT/mTOR signaling pathway in HR+ breast cancer by Cui Chen, Zehong Chen, Jinze Zhao, Xinyun Wen, Hanming Yao, Zijin Weng, Huiping Xiong, Zongheng Zheng, Juekun Wu

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Factors influencing the natural history of non-IgE-mediated gastrointestinal food allergies in paediatric age: a prospective multicentre cohort study by Giorgio Bedogni, Roberto Berni Canani, Laura Carucci, Rita Nocerino, Serena Coppola, Pasqualina Capasso, Veronica Giglio

“…Background We aimed at identifying the factors influencing the natural history of non-IgE-mediated gastrointestinal food allergies (non-IgE-GIFA), a group of common paediatric conditions including food protein–induced: enteropathy (FPE), allergic proctocolitis (FPIAP), enterocolitis syndrome (FPIES), and motility disorders (FPIMD).Methods Prospective multicentre cohort study involving paediatric patients (both sexes, aged ≤14 y) with non-IgE-GIFA diagnosed and followed for 24 months at a Tertiary Centre for Paediatric Allergy, Gastroenterology and Nutrition. Anamnestic and clinical data were collected from all enrolled patients.Results 123 non-IgE-GIFA patients were enrolled (56% male, median age (IQR) 150 (60–300) days): FPE (39%), FPIES (17%), FPIAP (16%) and FPIMD (28%). 42% of patients had multiple food allergies (FAs) at baseline, and 64% had a positive family history of allergy. …”
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Sphingosine kinase 1 promotes M2 macrophage infiltration and enhances glioma cell migration via the JAK2/STAT3 pathway by Zihan Song, Zijun Zhao, Xuehua Liu, Yiran Song, Siyu Zhu, Ziyang Jia, Yijie Li, Zairan Wang, Boyu Sun, Qianxu Jin, Shiyang Zhang, Zongmao Zhao, Liqiang Liu

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Mitigating effects of Jiawei Chaihu Shugan decoction on necroptosis and inflammation of hippocampal neurons in epileptic mice by Qin Wang, Baijun Qin, Han Yu, Jiawei Zeng, Jingjing Fan, Qiong Wu, Rong Zeng, Haichun Yu, Xian Zhang, Mingfen Li, Yanying Zhou, Limei Diao

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Pre-diagnostic risk factors for brain cancer incidence and survival: insights from the Golestan Cohort Study by Parisa Rezanejad-Asl, Peyvand Parhizkar Roudsari, Negar Rezaei, Maryam Sharafkhah, Gholamreza Roshandel, Hossein Poustchi, Sadaf Sepanlou, Reza Malekzadeh

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The Effects of Digital eHealth Versus Onsite 2-Day Group-Based Education in 255 Patients With Irritable Bowel Syndrome: Cohort Study by Birgitte Berentsen, Camilla Thuen, Eline Margrete Randulff Hillestad, Elisabeth Kjelsvik Steinsvik, Trygve Hausken, Jan Gunnar Hatlebakk

“…MethodsPatients diagnosed with IBS, aged 15-70 years, were enrolled after referral to the Section of Gastroenterology at Haukeland University Hospital, Norway. …”
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Nonlinear associations of the hs-CRP/HDL-C index with metabolic dysfunction-associated steatotic liver disease and advanced liver fibrosis in US adults: insights from NHANES 2017–2... by Bin Liang, Xue Qiu, Jiansheng Huang, Yequan Lu, Hairong Shen, Jianchao Ma, Yongyu Chen

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Plant-nanoparticles enhance anti-PD-L1 efficacy by shaping human commensal microbiota metabolites by Yun Teng, Chao Luo, Xiaolan Qiu, Jingyao Mu, Mukesh K. Sriwastva, Qingbo Xu, Minmin Liu, Xin Hu, Fangyi Xu, Lifeng Zhang, Juw Won Park, Jae Yeon Hwang, Maiying Kong, Zhanxu Liu, Xiang Zhang, Raobo Xu, Jun Yan, Michael L. Merchant, Craig J. McClain, Huang-Ge Zhang

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Tolerability and Effectiveness of Regorafenib Treatment in Patients with Unresectable Hepatocellular Carcinoma: Real-World Data from the United States by Finn RS, Iyer R, Kalman RS, Parikh ND, Cabrera R, Babajanyan S, Kaseb AO

“…Richard S Finn,1 Renuka Iyer,2 Richard S Kalman,3 Neehar D Parikh,4 Roniel Cabrera,5 Svetlana Babajanyan,6 Ahmed O Kaseb7 1Department of Medicine, University of California, Los Angeles, CA, USA; 2Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY, USA; 3Department of Medicine, Einstein Medical Center, Philadelphia, PA, USA; 4Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA; 5Department of Medicine, University of Florida Health, Gainesville, FL, USA; 6US Medical Affairs, Oncology, Bayer Healthcare, Whippany, NJ, USA; 7Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USACorrespondence: Richard S Finn, Department of Medicine, University of California, Los Angeles, CA, USA, Tel +1-310-586-2091, Email rfinn@mednet.ucla.eduIntroduction: While several systemic therapies are available for unresectable hepatocellular carcinoma (uHCC), there is a lack of granular real-world evidence to support the efficacy and safety of these therapies. …”
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IRG1/itaconate enhances efferocytosis by activating Nrf2-TIM4 signaling pathway to alleviate con A induced autoimmune liver injury by Liwu Zeng, Yaxin Wang, Yongzhou Huang, Wenchang Yang, Pei Zhou, Yaqi Wan, Kaixiong Tao, Ruidong Li

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Kaempferol protects against high-salt-induced hypertension and vascular endothelial injury by inhibiting ferroptosis through the ATF4/ACSL4 pathway by Qiuer Liang, Minghao Chen, Guangtian Chen, Pengli Xu, Lai Kwan Lam, Pengcheng Xie, Ting Xie, Wanqing Tu, Tianhao Liu, Xiaopeng Peng, Haoyao Yuan, Liguo Chen, Ya Xiao

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Effects of time restricted feeding combined with Lacto Ovo vegetarian diet on metabolic associated fatty liver disease management: a randomized clinical trial by Mahshad Shafiee, Amir Sadeghi, Fateme Ghafouri-Taleghani, Maryam Nilghaz, Maryam Ghods, Behnaz Narimani, Azita Hekmatdoost, Atoosa saidpour

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Ultrasonographic Assessment of Intima-Media Thickness (IMT), as a Surrogate of Future Atherosclerosis and Cardiac Diseases in Patients with Hashimoto’s Thyroiditis and Concomitant... by Maryam Alaei, Mohamad Ghazanfari Hashemi, Seyedeh Nooshin Miratashi Yazdi, Mohammad Ali Kaviani, Ali Asadifar, Sahand Adib Moradi, Khazar Adibmoradi Langaroudi, Helia Helali, Mina Mahboudi, Aynaz Gerami

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Nonlinear association between glycated hemoglobin levels and mortality in elderly patients with non-diabetic chronic kidney disease: a national health and nutrition examination sur... by Lihua Huang, Liuliu He, Qingfeng Zeng, Jinjing Huang, Xiaoyan Luo, Qiuming Zhong

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