Combined analysis of 16S rRNA gene sequencing data reveals core vaginal bacteria across livestock species by Lucille C. Jonas, Lucille C. Jonas, Curtis R. Youngs, Stephan Schmitz-Esser, Stephan Schmitz-Esser

“…A better understanding of the livestock vaginal microbiota is required for future studies aimed at elucidation of the functional significance of individual microbes with respect to livestock reproductive efficiency. …”
Get full text

Accuracy of Lung Ultrasonography for Diagnosis of Heart Failure; a Systematic Review and Meta-analysis by Erfan Rahmani, Masoud Farrokhi, Mehrdad Farrokhi, Shadi Nouri, Atousa Moghadam Fard, Behnam Hoorshad, Ramin Atighi, Erfan Ghadirzadeh, Michael Tajik, Habibollah Afshang, Aida Naseri, Mohadeseh Asoudehfard, Shiva Samami Kojidi, Arsham Ebnemehdi, Mehdi Rezaei, Maziar Daneshvar, Amirali Makhmalbaf, Sepideh Hassanpour Khodaei, Shirin Farsi, Saber Barazandeh Rad, Fateme Nozari, Pouya Rezaei, Negar Babapour, Salman Delavar, Babak Goodarzy, Lida Zare Lahijan, Sanam Mohammadzadeh, Helena Mehran, Fatemeh Gheibi, Ramtin Shemshadigolafzani, Behnaz Dalvandi, Amir Abderam

“…However, the influence of outlier and influential studies warrants caution, and future studies should aim to further validate these findings in diverse clinical contexts. …”
Get full text

Psychosocial distress, perceived need and utilization of psycho- social support services in patients in the early phase after the first cancer diagnosis by Hannah Zingler, Diana Steinmann, Jochen Ernst, Ute Goerling, Myriel Hermann, Beate Hornemann, Anja Mehnert-Theuerkauf, Tanja Zimmermann

“…These should be investigated in more detail in future studies.…”
Get full text

Machine Learning in the Management of Patients Undergoing Catheter Ablation for Atrial Fibrillation: Scoping Review by Aijing Luo, Wei Chen, Hongtao Zhu, Wenzhao Xie, Xi Chen, Zhenjiang Liu, Zirui Xin

“…While guiding data preparation and model selection for future studies, this review highlights the need to address prevalent limitations, including lack of external validation, and to further explore model generalization and interpretability.…”
Get full text

Agreement Between Provider-Completed and Patient-Completed Preoperative Frailty Screening Using the Clinical Risk Analysis Index: Cross-Sectional Questionnaire Study by Mehraneh Khalighi, Amy C Thomas, Karl J Brown, Katherine C Ritchey

“…ConclusionsRAI-C had moderate agreement when completed by providers versus the participants themselves, with more than a third of patient-completed screens resulting in a higher frailty classification. Future studies will need to explore the differences between and accuracy of RAI-C screening approaches to inform best practices for preoperative RAI-C assessment implementation.…”
Get full text

Biological subphenotypes in patients hospitalized with suspected infection in Thailand: a secondary analysis of a prospective observational studyResearch in context by Prapassorn Poolchanuan, Taylor D. Coston, Viriya Hantrakun, Parinya Chamnan, Gumphol Wongsuvan, Pavan K. Bhatraju, Narisara Chantratita, Direk Limmathurotsakul, T. Eoin West, Shelton W. Wright

“…Patient subphenotype assignment was characterized by distinct clinical outcomes and biological profiles which could inform contextualized future study design. Funding: The US National Institutes of Health, the Wellcome Trust, and the Firland Foundation.…”
Get full text

The causal relationship of cigarette smoking to metabolic disease risk and the possible mediating role of gut microbiota by Jingda Zhang, Lin Hou, Shanxiang Lei, Yan Li, Guogang Xu

“…Conclusion: This work offered genetic evidence linking cigarette smoke to metabolic diseases, suggesting that the gut microbiota, particularly paraprevotella_clara, might be a crucial mediator in the development of type 2 diabetes caused by cigarette smoke. Our future studies should consider conducting other ethnic groups MR analyses, particularly with larger sample sizes. …”
Get full text

Weight Change and Predictors of Weight Change Among Patients Initiated on Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide or Bictegravir/Emtricitabine/Tenofovir Alafenamid... by Bruno Emond, Carmine Rossi, Aurélie Côté-Sergent, Keith Dunn, Patrick Lefebvre, Marie-Hélène Lafeuille, Prina Donga

“…Weight gain is an important factor to consider when selecting antiretroviral regimens, since it is associated with long-term health consequences. Future studies with larger sample size and longer follow-up time are warranted.…”
Get full text

Assessing awareness and treatment knowledge of preventable blindness in rural and urban South African communities by Z Kiva, J E Wolvaardt

“…Without this, there will be little demand for any treatment or service. Future studies are needed to understand which health promotion interventions are effective in preventable blindness in rural populations. …”
Get full text

Genome data based deep learning identified new genes predicting pharmacological treatment response of attention deficit hyperactivity disorder by Yilu Zhao, Zhao Fu, Eric J. Barnett, Ning Wang, Kangfuxi Zhang, Xuping Gao, Xiangyu Zheng, Junbin Tian, Hui Zhang, XueTong Ding, Shaoxian Li, Shuyu Li, Qingjiu Cao, Suhua Chang, Yufeng Wang, Stephen V. Faraone, Li Yang

“…Furthermore, our CNN model exhibited good performance in an independent dataset, encouraged future studies and implied potential clinical applications.…”
Get full text

MUC5B modulation of early oral biofilm glucose metabolism by Carolina Robertsson, Carolina Robertsson, Julia Davies, Gunnel Svensäter, Anders Bay Nord, Niclas Norrström, Claes Wickström

“…Such core metabolomes can be used to detect deviations in future studies. Significant differences in metabolite abundance elicited by the presence of MUC5B were also detected. …”
Get full text

Researcher views on returning results from multi-omics data to research participants: insights from The Molecular Transducers of Physical Activity Consortium (MoTrPAC) Study by Kelly E. Ormond, Caroline Stanclift, Chloe M. Reuter, Jennefer N. Carter, Kathleen E. Murphy, Malene E. Lindholm, Matthew T. Wheeler

“…However, competing ethical considerations, logistical constraints, and need for more external guidance were raised as key implementation concerns. Future studies should consider views and experiences of other relevant stakeholders, specifically clinical genomics professionals and study participants, regarding the clinical utility of multi-omics information and multi-omics results return.…”
Get full text

Global trends and research frontiers on machine learning in sustainable animal production in times of climate change: Bibliometric analysis aimed at insights and orientations for t... by Robson Mateus Freitas Silveira, Concepta Mcmanus, Iran José Oliveira da Siva

“…The main insights generated in the bibliometric analysis were (i) sustainable animal production changed from unidisciplinary science to multidisciplinary science linked to agricultural, environmental and engineering sciences, mainly to genetics and computing; (ii) the concept of sustainable animal production emerged from animal welfare and climate change concepts found in UN's 2030 Agenda; (iii) omics sciences, greenhouse gases, energy efficiency and animal welfare are the main keywords for bibliometric analyses in future studies related to sustainable animal production in the coming centuries; (iii) prediction and classification analyses, i.e., supervised machine learning models used as main tools in animal production; (iv) residual feed intake applied to measure sustainable feed efficiency in animal farming in the past and nowadays; and (v) The United States, China, Brazil and Australia are the main countries publishing studies on sustainability in animal production, but only China has been gaining prominence in publications in this field, in recent years, and it will turn this country into an emerging leader in future publications on this topic. …”
Get full text

Prevalence and Factors Associated with Iron Deficiency Among Children Aged 6 Months to 12 Years Attending the Sickle Cell Clinic at Kitete Hospital Tanzania. by Lubeja, Amos Charles (M.D)

“…Deworming is recommended for children with Sickle Cell Anaemia, and those with H. pylori infection should receive appropriate treatment as per guidelines. Future studies on iron deficiency in children with Sickle Cell Anaemia should consider testing serum hepcidin levels to identify candidates suitable for safe iron supplementation.…”
Get full text

Profile of non-invasive physical health indicators associated with cognitive performance in Chinese older adults: evidence from the China Health and Retirement Longitudinal Study by Xiyu Wei, Chao Li, Dongyu Liu, Jieyi Chen, Yumeng Ju, Jin Liu, Bangshan Liu, Yan Zhang

“…Conclusions A profile of non-invasive physical health indicators associated with cognitive performance was established, which warrants future incorporation of non-invasive physical health indicators in early risk screening systems for MCI, enabling timely intervention and prevention in older adults. Future studies can delve deeper into the mechanisms underlying this full-dimensional relationship between physical and cognitive domains.…”
Get full text

Safety of influenza vaccination during pregnancy: a systematic review by Brian Hutton, David Moher, Danielle B Rice, Claire Butler, Andrea C Tricco, Becky Skidmore, Candyce Hamel, Chantelle Garritty, Paul A Khan, Marco Ghassemi, Charlene Soobiah, Leila Esmaeilisaraji, Dianna M Wolfe, Deshayne Fell, Mona Hersi, Nadera Ahmadzai, Alan Michaud, Angela Sinilaite

“…Appropriate control of confounding and temporal biases in future studies would improve the evidence base.…”
Get full text

Viral load suppression rate of third-line antiretroviral therapy and its association with gender among HIV patients after second-line treatment failure in Africa: a systematic revi... by Tilahun Degu Tsega, Sintayehu Simie Tsega, Asaye Alamneh Gebeyehu, Getaneh Atikilt Yemata, Rahel Mulatie Anteneh, Almaw Genet Yeshiwas, Getasew Yirdaw, Chalachew Yenew, Anley Shiferaw Enawgaw, Amare Genetu Ejigu, Ahmed Fentaw Ahmed, Zeamanuel Anteneh Yigzaw, Berhanu Abebaw Mekonnen, Meron Asmamaw Alemayehu, Abathun Temesgen, Abebaw Molla, Habitamu Mekonen, Assefa Andargie Kassa, Gashaw Melkie Bayeh

“…Therefore, to maintain and further improve the strong viral load suppression rates of TLARVT in Africa, it is essential to focus on appropriate regimen selection, patient counseling and switching, adherence support, and regular viral load testing. Future studies with larger sample sizes should explore the association between gender and viral load suppression to provide conclusive findings.…”
Get full text

Proposal and Strategy for Nursing-Led Research: Protocol for an Unfunded Clinical Trial by Leticia Carmen Simón-López, Ismael Ortuño-Soriano, Raquel Luengo-González, Paloma Posada-Moreno, Ignacio Zaragoza-García, Rubén Sánchez-Gómez

“…This is why initiatives to conduct unfunded clinical trials have been identified as an important issue to pay attention to in future studies. Therefore, we present our initiative through Rogers’ theory, which is highlighted in the literature for diffusing innovative change across organizations. …”
Get full text

Determinants of fertility in timed artificial insemination programs in beef cattle: predictive ability and risk factors from almost 2 million data points by R.E.F. Assis, F. Baldi, L.B. Temp, R. Ungerfeld, M.F. de Sá Filho

“…Despite the influence of each factor, this study demonstrated the usefulness of analyzing big databases, allowing to determine effects that cannot be studied with experimental approaches, providing a complementary approach to decide where to focus future studies to enhance TAI pregnancy rates in beef cattle.…”
Get full text

Association of lower-limb strength with different fall histories or prospective falls in community-dwelling older people: a systematic review and meta-analysis by Ringo Tang-Long Zhu, Jenny Jing-Jing Zuo, Ke-Jing Li, Freddy Man Hin Lam, Arnold Yu Lok Wong, Lin Yang, Xue Bai, Man Sau Wong, Timothy Kwok, Yong-Ping Zheng, Christina Zong-Hao Ma

“…Tests of entire lower-limb power required the cumulative and coordinated contractions of more leg muscles, possibly explaining why they could identify the fallers whereas the RTD or power of a single muscle group could not. Future studies are warranted to determine cut-point values of the entire lower-limb power measurements in fall-risk assessment and explore rapid force generation of a single muscle group in predicting the injurious falls among older adults. …”
Get full text