Pancreatic exocrine insufficiency after pancreatic resection: a systematic review by Marcello Di Martino, Ángela de la Hoz Rodriguez, Andrea Saibanti, Guillermo Salvador Camarmo, Nico Pagano, Elena Martín-Pérez, Matteo Donadon

“…Additionally, few studies report on micronutrient deficiencies, variations in anthropometric data or PEI-related patient-reported outcomes. Future studies should aim to establish a gold standard for diagnosis and severity assessment of post-pancreatectomy PEI and provide guidance for tailored pancreatic enzyme replacement therapy.…”
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Evaluation of a Novel Water-Based Automated Endoscope Cleaning Process Compared to Conventional Manual Cleaning for Reducing Duodenoscope Contaminatio by Koen van der Ploeg, Juliëtte A. Severin, Margreet C. Vos, Nicole S Erler, Adriana J.C. Bulkmans, Marco Bruno, Bibi C.G.C. Mason-Slingerland

“…These results are promising. However, future studies should confirm these findings in larger samples and explore the other advantages of using the AT in duodenoscope cleaning. …”
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Assessing psychological health and reproductive function: Depression, anxiety, and stress in infertile men compared to controls: A case-control study by Seyedeh Narjes Roudbaraki, Maryam Ramezani, Bita Saifi, Mostafa Salimi, Massood Issapour Cheshani

“…Limitations included phone-based data collection and the depression, anxiety, and stress scale 21 questionnaire’s screening nature. Future studies should involve larger populations and consider economic status as a variable related to mental health. …”
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Exposure pathways (diet, dissolved or particulate substrate) of rare earth elements to aquatic organisms by Ashlyn Kernaghan, Duc Huy Dang

“…Nevertheless, our results confirming preferential uptake pathways of the six organisms can help select appropriate species in future studies to monitor REE exposure from vaious fractions: dissolved, particulate forms or in the food webs (i.e., diet).…”
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The Association between Ambient Fine Particulate Matter and Oral Neoplasm among Smokers and Betel Quids Chewers by Mei-Sheng Ku, Pallop Siewchaisakul, Amy Ming-Fang Yen, Chen-Yu Liu

“…Subjects from areas of higher PM2.5 levels were found to have greater risk of OPMD/OC in Taiwan. Future studies are warranted to investigate the effect of personal PM2.5 exposure on OPMD/OC risk.…”
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Individualized drug therapy and survival prediction in ICU patients with acute kidney injury: construction and validation of a nomogram by Rui Yang, Xiaozhe Su, Ziqi Liu, Shuai Shao, Yinhuai Wang, Hao Su, Haiqing He

“…Conclusions In summary, the developed prediction model demonstrated accuracy for AKI patients in the ICU and helped clinical decision-making. However, future studies will require external validation to confirm these findings.…”
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Optimal needle characteristics for classical inferior alveolar nerve block anesthesia: a systematic review by Mennat Allah Ashraf Abd-Elsabour, Ayat Gamal-AbdelNaser

“…Clinical relevance Thinner needles are favored for less pain during insertion; but standardized future studies are essentially needed for solid conclusions. …”
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Zinc levels in severe eating disorders by Kara Leach, Dan V. Blalock, Judy Oakes, Melanie Hebert, Marina Foster, Philip S. Mehler

“…These characteristics make zinc an intriguing focus of future study that could impact the recidivism rate in severe ED. …”
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Nurses retention: the impact of transformational leadership, career growth, work well-being, and work-life Balance by Eman Sameh AbdELhay, Samah Mohamed Taha, Mona Metwally El-Sayed, Sahar Hassan Helaly, Islam Sameh AbdELhay

“…Healthcare institutions should focus on transformational leadership and work-life balance to enhance nurse retention. Future studies should explore factors related to career growth and work well-being to determine their potential impact on retention.…”
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Impact of elexacaftor-tezacaftor-ivacaftor in lung transplantation for cystic fibrosis in the United States by Tahuanty A. Pena, MD, MS, Brittany Wright, PharmD, Kalpaj R. Parekh, MBBS, Julia Kleney-Tait, MD, PhD

“…These findings underscore the transformative impact of CFTR modulators like ETI on the natural history of CF, highlighting the importance of continued advancements in precision medicine for genetic disorders. Future studies should investigate long-term outcomes and sustained trends in lung transplantation needs among pwCF.…”
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Real-World Treatment Patterns in Men with Castration- Resistant Prostate Cancer Receiving Docetaxel by Keith L. Davis, Benjamin Gutierrez, Teresa Zyczynski, James A. Kaye

“…However, one quarter of patients did not initiate docetaxel until ≥6 months after CRPC diagnosis and total exposure varied considerably, with only 10% receiving ≥10 cycles. Future studies are needed to describe specific reasons explaining timing of docetaxel initiation and duration of exposure in some CRPC patients.…”
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Development of Predictive Models for Progression from Diabetic Kidney Disease to End-Stage Renal Disease in Type 2 Diabetes Mellitus: A Retrospective Cohort Study by Hu H, Mu X, Zhao S, Yang M, Zhou H

“…Additionally, the combined model of KFRE, IFTA, SII, and BMI demonstrates high predictive performance. Future studies should validate these models in larger cohorts and explore their integration into routine clinical practice to enhance personalized risk assessment and management.Keywords: diabetic kidney disease, end-stage renal disease, pathologies, risk assessment…”
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Novel insights into palatal shelf elevation dynamics in normal mouse embryos by Jeremy P. Goering, Michael Moedritzer, Marta Stetsiv, Dona Greta Isai, Brittany M. Hufft-Martinez, An J. Tran, Zaid Umar, Madison K. Rickabaugh, Paul Keselman, Munish Chauhan, Pamela V. Tran, William M. Brooks, William M. Brooks, Kenneth J. Fischer, Andras Czirok, Andras Czirok, Irfan Saadi, Irfan Saadi

“…Thus, our data reveal novel insights into rapid dynamic changes during PS elevation, and lay the foundation for future studies of normal and abnormal palatogenesis.…”
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Does a Provider Contact Wristband Reduce Emergency Department Visit Rates Following Hip or Knee Arthroplasty? by David C. Hein, MD, Ajay K. Srivastava, MD, Seann E. Willson, MD, Paul M. Telehowski, MD, Patrick J. Atkinson, PhD, Theresa S. Atkinson, PhD

“…Conclusions: Patients utilized the wristband number, but this did not significantly reduce the number of ED visits within 3 years. Future studies should track ED visits and identify decision-making factors behind ED use in order to find ways to improve the intervention.…”
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Phytomedicinal armamentarium: A review of inula racemosa-derived alantolactones and isoalantolactones in anticancer therapy by Joshi Gaurav Santoshrao, Smriti Jamwal, Rakesh Kumar, Ekta Bisht, Bisen Harsh Krishnakumar, Shreya Katoch, R.K. Asrani

“…Their diverse mechanisms of action and minimal side effects position them as candidates for further research and development. Future studies should focus on clinical trials to establish their efficacy and safety in humans, paving the way for new cancer therapies.…”
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The association between TyG index and cardiovascular mortality is modified by antidiabetic or lipid-lowering agent: a prospective cohort study by Changchang Fang, Nanqin Peng, Jiang Cheng, Xiyu Zhang, Wenli Gu, Zicheng Zhu, Xiaoping Yin, Zhiwei Yan, Jing Zhang, Peng Yu, Xiao Liu

“…These findings suggest that future studies on the TyG index and its relationship with CVD and mortality should account for the modifying effects of these agents. …”
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Smartphone apps for mental health: systematic review of the literature and five recommendations for clinical translation by Aljawharah Almuqrin, Ryan Hammoud, Ilham Terbagou, Stefania Tognin, Andrea Mechelli

“…This review proposes five recommendations for improving clinical translation in future studies.…”
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How defensive medicine is defined in European medical literature: a systematic review by Nathalie Baungaard, Elisabeth Assing Hvidt, Helle Gerbild, Merethe Kirstine Andersen, Jesper Lykkegaard, Pia Ladeby Skovvang

“…In order to compare results pertaining to defensive medicine across countries, future studies are recommended to specify whether they are using the narrow or broad definition of defensive medicine.PROSPERO registration number CRD42020167215.…”
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Evaluation of Treatment Patterns and Maintenance Dose Titration Among Patients With Crohn’s Disease Initiating Biologics With 3 Years of Follow-Up by Ruizhi Zhao, Zhijie Ding, Parul Gupta, Laurence Gozalo, Robert Bruette, Victor M. Johnson, Keshia Maughn, Yihang Liu, Sumesh Kachroo

“…**Conclusions:** Patients with CD on UST had the highest persistence and lowest dose escalation across different biologic users over the 3-year follow-up period, possibly suggesting a better clinical response of UST. Future studies with longer follow-up adjusting for confounders are needed to better understand treatment patterns among biologics users.…”
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The Effects of Soft Tissue Flossing on Hamstring Range of Motion and Lower Extremity Power by Zachary Maust, Debbie Bradney, Sean M Collins, Caroline Wesley, Thomas G Bowman

“…Flossing could be beneficial when treatment or performance preparation goals are increased flexibility without decreased power. Future studies should continue to examine the clinical effectiveness of flossing on an injured population.…”
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