Neoadjuvant chemoimmunotherapy for locally advanced squamous cell carcinoma of the head and neck: Systematic review and meta-analysis by Xiayi Zhu, Jie Qiu, Ya Zhang, Chunni Lin, Xiaohui Wang, Xiwei Shi, Siya Yang, Qiaoyan Wu, Li Cong

“…No significant differences were found in overall survival (OS) (hazard ratio: 0.85, 95 % CI: 0.77–0.93) and progression-free survival (PFS) (hazard ratio: 0.72, 95 % CI: 0.61–0.86). …”
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Outcomes of Surgical Treatment of Multiple Primary Colorectal and Prostate Cancer by I. S. Ignatov, V. V. Balaban, E. A. Bezrukov, A. V. Nikishina, M. He, P. V. Tsarkov

“…No significant differences were found when comparing overall and recurrence-free survival in groups with metachronous and synchronous variants of multiple primary cancer.Conclusions. …”
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Exploring the antimicrobial and antioxidative potential of Leucas aspera (Willd.) link: Phytochemical screening, molecular docking, and HR-LC/MS profiling against SARS-CoV-2 protei... by Thavasiaanatham Seenivasan Shalini, Ragothaman Prathiviraj, Poomalai Senthilraja

“…Methods: The L. aspera methanolic leaf extract displayed a phenolic content of 100 µg/ml, consisting of 3.02 mg of gallic acid dry weight equivalents and a flavonoid content of 100 µg/ml with 3.35 mg quercetin equivalents per dry weight. The extract's free radical scavenging capabilities were at 150 µg/ml in DPPH, showing an 87 % effectiveness compared to the standard ascorbic acid 49 % inhibition capacity. …”
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Genomic characterization and molecular predictive biomarkers for chemotherapy in patients with metastatic triple-negative breast cancer treated in a real-world setting by Erik Olsson, Henrik Lindman, Evangelos Digkas, Viktoria Thurfjell, Haidar Mir Ali, Ute Krüger, Anna-Karin Wennstig, Marie Sundqvist, Antonios Valachis

“…Altered genes and pathways were correlated with overall survival (OS) and evaluated regarding their association with real-world progression-free survival (rwPFS) in patients treated with different chemotherapy agents. …”
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PI3Kδ inhibitor linperlisib combined with gemcitabine and oxaliplatin for relapsed or refractory diffuse large B-cell lymphoma: a multicenter, single-arm phase Ib/II trial by Peng Sun, Hong Cen, Haiyan Yang, Rui Huang, Zhen Cai, Xuekui Gu, Hanying Bao, Zusheng Xu, Zuhong Xu, Zhi-Ming Li

“…The median duration of response was 5.7 months (95% CI: 4.3–9.1), and the median progression-free survival was 5.4 months (95% CI: 1.8–6.7). The 1-year OS rate was 65.5% (95% CI: 48.1–78.3). …”
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UV-Vis spectroscopy and chemometric: a simple method to differentiate honey, partially ripe honey and nectars by L. M. Maldonado, K. Marcinkevicius, A.R. Álvarez, V.M. Salomón, M. Gaggiotti, N. Messina, M.A. Palacio, S. Medina, M.M. Maldonado, E. Orellano, E. L. Bedascarrasbure

“…Se registraron espectros entre 190 nm y 420 nm y se aplicaron diferentes métodos de proyección, incluyendo el análisis de componentes principales, FreeViz y el análisis discriminante lineal. De los resultados se concluye que la espectroscopía UV-Vis acoplada al análisis quimiométrico permite diferenciar el néctar recientemente recolectado de la miel parcialmente madura y de la miel y que los compuestos fenólicos están presentes principalmente en la miel, lo que podría incidir favorablemente en su actividad biológica.…”
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Prevalence and associated factors of intestinal parasitic infections in the Badi indigenous communities of Western Nepal by Jitendra Gautam, Rajendra Prasad Parajuli, Kishor Pandey

“…The multivariate logistic regression analysis revealed increased odds of IPIs among participants involved in agriculture [aOR: 5.37, 95% CI: (2.31 to 12.47)], those who kept free-ranging pigs and poultry [aOR: 5.22, 95% CI: (1.87 to 14.53)], those who did not use soap before eating [aOR: 9.96, 95% CI: (2.11 to 46.99)], and those who consumed raw or undercooked meat [aOR: 2.76, 95% CI: (1.08 to 7.05)] compared with others. …”
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Diagnosis and treatment of thyroblastoma: a case report and review of literature by Xiting Chen, Xiting Chen, Lijuan Xiong, Lijuan Xiong, Hongling Liu, Haoqiang Wang, Donghai Cheng, Wei Wang, Wenyuan He, Bo Xie, Juan Zhou

“…The patient’s progression-free survival (PFS) reached 15 months following the administration of BEP chemotherapy in conjunction with local radiotherapy. …”
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NAPTUNE: nucleic acids and protein biomarkers testing via ultra-sensitive nucleases escalation by Tao Hu, Xinxin Ke, Yingying Yu, Hongmei Feng, Senfeng Zhang, Yinuo Cui, Boyang Zhang, Min He, Yinbing Tang, Lei Liu, Yu Lin, Quanquan Ji, Chuanxia Chen, Chunlong Xu, Chunyi Hu

“…Abstract In an era where swift and precise diagnostic capabilities are paramount, we introduce NAPTUNE (Nucleic acids and Protein Biomarkers Testing via Ultra-sensitive Nucleases Escalation), an innovative platform for the amplification-free detection of nucleic acids and protein biomarkers in less than 45 minutes. …”
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Multicomponent intervention for schoolchildren with asthma: Pilot cluster randomized controlled trial by Marina Reznik, MD, MS, Florinda Islamovic, MD, Jill S. Halterman, MD, MPH, Cheng-Shiun Leu, PhD, Jiaqing Zhang, PhD, Philip O. Ozuah, MD, PhD

“…Objective: We assessed preliminary effectiveness of a pilot multicomponent asthma intervention that includes classroom-based PA, asthma education to increase knowledge and reduce stigma, and care coordination to facilitate guideline-based care, on PA and symptom-free days (SFD) in urban, historically marginalized children with asthma. …”
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Ventricular function assessment using an ultrafast spoiled gradient echo sequence with an intravascular blood pool contrast agent in pediatric patients. by Tayaba Miah, Rithvik Gunda, Gerald Greil, Mohammad Hussain, Qing Zou

“…<h4>Background</h4>Balanced steady-state free processing (bSSFP) MR sequence has long been considered the gold standard method for ventricular function assessment (VFA), and normal values are based on this acquisition. …”
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The dual impact: physiological and psychological effects of rapid weight loss in wrestling by Barış Sarıakçalı, Fatma Neşe Şahin, Burhan Başoğlu, Levent Ceylan, Özkan Güler, Bade Yamak, Gökhan Arıkan, Gizem Ceylan Acar, Gülşah Sekban, Mehmet Vakıf Durmuşoğlu, Sezen Çimen Polat, Hamza Küçük

“…This study aimed to investigate the biochemical, hormonal, and psychological effects of weight reduction in elite wrestlers during the competition phase.MethodsThirty-seven elite male free style wrestlers (age: 19.02 ± 1.27) participated in the study. …”
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SPAGRM: effectively controlling for sample relatedness in large-scale genome-wide association studies of longitudinal traits by He Xu, Yuzhuo Ma, Lin-lin Xu, Yin Li, Yufei Liu, Ying Li, Xu-jie Zhou, Wei Zhou, Seunggeun Lee, Peipei Zhang, Weihua Yue, Wenjian Bi

“…SPAGRM can utilize GRM-free models and thus is applicable to various trait types and statistical methods, including linear mixed models and generalized estimation equations for longitudinal traits. …”
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Soil Erosion Process Under the Combined Action of Water and Gravity on Red Soil Slope by ZHANG Xiaohan, MA Lan, YU Chong, WU Zhiwei, WANG Jie

“…Through the method of artificial simulation of continuous rainfall in the field, the influence of gravel content on soil erosion process and its synergistic change rule under the combined action of water and gravity were discussed. [Results] (1) Gravel-free soil did not produce runoff under two rainfalls. …”
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Permeability-Enhancing and Protective Effect on Small Intestine of Punicic Acid in Different Forms and Their Nanoemulsions With Low Toxicity by Duan D, Xie H, Jiang J, Yang P, Guo Z, Guo X, Chen X, Yao Q

“…Setting oleic acid (OA) as the control, the three forms of punicic acid (PA), ie, free PA, PAEE, and pomegranate seed oil, in which PA exists in the form of triglyceride, were formulated into nanoemulsions (NE). …”
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The prognostic value of the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in colorectal cancer and colorectal anastomotic leakage patients: a retrospe... by Nuo Xu, Jian-Xin Zhang, Jia-Jie Zhang, Zhuo Huang, Lian-Chun Mao, Zhi-Yong Zhang, Wei-Dong Jin

“…Kaplan–Meier survival curve results showed that 5-year overall survival (OS) and disease-free survival (DFS) in the low NLR and PLR group were significantly higher than those in the high NLR and PLR group. …”
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Effects of perioperative treatment of resectable adenocarcinoma of esophagogastric junction by immunotherapy (Adebrelimab) combined with chemotherapy (XELOX): protocol for a single... by Yingyi Li, Yuqin Cao, Xipeng Wang, Chengqiang Li, Liqin Zhao, Hecheng Li

“…Secondary outcomes of the study include the objective response rate (ORR), R0 resection rate, major pathological response (MPR) rate, and pCR rate in combined positive score(CPS) ≥ 5 and MSI-H populations, event-free survival (EFS), and overall survival (OS). The exploratory outcomes are the biomarkers related to therapeutic efficacy, such as PD-L1 expression, microsatellite instability (MSI), tumor mutational burden(TMB), Epstein-Barr virus(EBV) infection, and circulating tumor DNA(ctDNA). …”
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Factors Affecting Utilization of Insecticide Treated Nets in Households Among Children Under Five Years of Age in Kazo Town Council, Kazo District. by Tumwebaze, Rodgers

“…The study recommended that plans be made to increase the number of free ITN s distributed to households, increase in community education and public awareness on ITN use.…”
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Factors Affecting Male Involvement in Family Planning at Kazo Health Center IV in Kazo Town Council Kazo District. by Ndyaguma, Laban

“…On recommendation the government should establishment of men's clinics so that men can feel free to go and utilize the services. The services should be user friendly to men in order to be utilized to the maximum Male only clinics should inform men about all family planning methods and provide condoms and vasectomy and counsel men with respect and sensitivity, more so Education, men need a lot of information on family planning so that they are well informed.…”
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Review of the Effectiveness of the Existing Municipal Solid Waste Management Systems in Uganda. Case Study of Kabale Municipal Council, Kabale Municipality, Kabale District. by Ainebyona, Joseph

“…Therefore, there is need for KMC to include all the people in working for the clean and health threat-free environment. The study also suggest that KMC should try to effect the existing systems plus adopting the modern techniques for the collection, transportation and disposing of solid waste in Kabale Municipality.…”
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