Network Meta-Analysis of Once Weekly Selinexor-Bortezomib-Dexamethasone in Previously Treated Multiple Myeloma by Michael Dolph, Gabriel Tremblay, Adrienne M Gilligan, Hoyee Leong

“…**Methods**: Ovid was systematically searched for phase 2-3 randomized clinical trials (RCTs) in MM that assessed progression-free survival (PFS), overall survival (OS) and overall response rates (ORR). …”
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Case report: identification of novel variant in SLC26A2 gene and preimplantation genetic testing for monogenic disorders in preventing diastrophic dysplasia by Ziravard N. Tonyan, Yulia A. Nasykhova, Maria M. Danilova, Elena S. Shabanova, Olesya N. Bespalova, Igor Y. Kogan, Andrey S. Glotov

“…The successful application of PGT-M enabled the selection of an embryo free from inherited pathogenic variants from both parents, highlighting the importance of PGT-M in improving reproductive outcomes for affected families.…”
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Endometrial Carcinoma Presenting with an Isolated Osseous Metastasis: A Case Report by Nesrine Tounsi, Ines Zemni, Fatma Saadalah, Maher Slimane, Nadia Boujelbene, Mohamed ali Ayadi, Chargui Rhiad, Rahal Khaled

“…The patient is clinically free of disease 10 months following diagnosis. Single-bone extrauterine metastatic site and local disease limited to the uterus had better survival outcomes than Stage IVb endometrial cancer with multiple metastatic sites. …”
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Cost-effectiveness Analysis of Ribociclib plus Letrozole versus Palbociclib plus Letrozole in the United Kingdom by Gaurav Suri, David Chandiwana, Adam Lee, Rohit Mistry

“…**Results:** In the base case, treatment with ribociclib plus letrozole increased mean progression free survival (PFS) by 4.1 months and overall survival by 5.0 months compared to palbociclib plus letrozole. …”
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Enhanced brightness and photostability of dye-sensitized Nd-doped rare earth nanocomposite for in vivo NIR-IIb vascular and orthotopic tumor imaging by Syue-Liang Lin, Shih-Po Su, Yuan-Zhen Yang, Cheng-Yu Chiang, Hsin-Yu Chi, Cheng Allen Chang, Tse-Ying Liu, Huihua Kenny Chiang

“…In vivo imaging studies demonstrated a 75-fold increase in luminance and a 9-fold improvement in photostability compared to free NIR dyes in aqueous solutions. Time-dependent in vivo studies confirmed the nanocomposite’s capability for prolonged imaging of vascular and tumor tissues, maintaining high-resolution images for over an hour. …”
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Eco-friendly alkali-activated nano concrete: Impact of nano-GGBFS on mechanical and microstructural properties by Samuvel Raj R, G. Prince Arulraj, N. Anand, Balamurali Kanagaraj, Eva Lubloy

“…The addition of nGS also reduced the setting time and increased compressive strength, leading to a denser, crack-free matrix. However, excessive nGS beyond the optimal content resulted in non-uniform distribution due to agglomeration. …”
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Crystal structure modulating performances for 213-nm GeO2 solar-blind photodetectors via DC reactive magnetron sputtering method by Chengming Wei, Jiabao Liu, Xinru Lan, Cheng Yang, Shuiping Huang, Dongdong Meng, Zhengwei Chen, Hongguang Duan, Xu Wang

“…However, the precise control of the crystal structure and optical property is a huge challenge due to close free formation energies of multiple phases, inhibiting the GeO2 based practical device applications. …”
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Extracecellulr vesicles (EVs) microRNAs (miRNAs) derived from mesenchymal stem cells (MSCs) in osteoarthritis (OA); detailed role in pathogenesis and possible therapeutics by Seyede Sara Pakdaman Kolour, Saeide Nematollahi, Masoud Dehbozorgi, Farnaz Fattahi, Fatemeh Movahed, Neda Esfandiari, Mohammad Saeed Kahrizi, Nima Ghavamikia, Bahareh Salmanian Hajiagha

“…Further, attractive candidates for cell-free therapy for OA are MSC-derived extracecellulr vesicles (EVs) that convey bioactive molecules of the original cells, such as microRNAs. …”
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Development and validation of a new reverse-phase high-performance liquid chromatography (RP-HPLC) method for the quantifications of tolperisone loaded in liposomes by Rawan N. AlKaraki, Rula R. Haddadin, Shahed K. Tarawneh, Marwa A.M. Alimari, Rehan M. Alkasasbeh, Tebat Al-ferdous E. Shamaileh, Mustafa S. Almohtaseb, Malek G. Hajaya

“…The validated RP-HPLC method was used to demonstrate the suitability of liposomes as a carrier for TOL by evaluating its entrapment efficiency (14.76 %), along with achieving a slower drug in-vitro cumulative percentage release in the targeted media (compared to free TOL solution) from the liposomes.…”
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Distribution and clinicopathological characteristics of G-CSF expression in tumor cells and stromal cells in upper tract urothelial carcinoma by Go Kobayashi, Yohei Sekino, Hikaru Nakahara, Kohei Kobatake, Keisuke Goto, Tetsutaro Hayashi, Kazuhiro Sentani, Nobuyuki Hinata

“…Public data showed that G-CSF expression was also associated with decreased progression-free survival and disease-specific survival. A prognostic model was constructed by incorporating the presence or absence of G-CSF expression along with clinicopathologic factors, which allowed for a more accurate prediction of poor prognosis. …”
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Genomic insights and comparative analysis of Colletotrichum species associated with anthracnose fruit rot and crown rot of strawberry in North Carolina by Tika B. Adhikari, Norman Muzhinji, Ashley N. Philbrick, Frank J. Louws, Frank J. Louws

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ASSESSING THE EFFICACY OF CLOUD SERVICES FOR DEVELOPING EDUCATIONAL PRESENTATIONS by Tetiana V. Bondarenko, Nadia M. Stetsenko, Volodymyr P. Stetsenko, Halyna V. Tkachuk

“…This determination is grounded in their extensive functionality, provision of free accounts, and user-friendly interfaces. Analysis of domain ratings further highlighted the popularity of Sway, Canva, and Prezi, underscoring the pronounced demand for these platforms among users. …”
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Mechanistic studies on the effect of endogenous proteins on the starch retrogradation characteristics of corn before and after postharvest ripening by Nannan Hu, Weihua Qi, Jinying Zhu, Fuyin Zhao, Lin Xiu, Mingzhu Zheng, Jingsheng Liu

“…In addition, low field strength nuclear magnetic resonance (LF-NMR) analyses also revealed that proteins inhibited starch retrogradation by isolating the precipitation of free water during retrogradation, causing the decrease in the viscoelasticity and firmness of the starch gel. …”
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Examining tolerability, safety, and blinding in 1032 transcranial electrical stimulation sessions for children and adolescents with neuropsychiatric and neurodevelopmental disorder... by Andrea Battisti, Giulia Lazzaro, Luciana Ursumando, Barbara D’Aiello, Valeria Zanna, Floriana Costanzo, Stefano Vicari, Deny Menghini

“…Results showed tES safety with no “moderate” or “severe” AEs reported; about 77% of sessions were AE-free, supporting tES use in these populations. Itching was the most common symptom, and active sessions were found to be more likely to induce AEs compared to sham sessions. …”
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Changes in the nutrient composition of top-selling packaged foods and beverages in Colombia between 2016 to 2021 by Luis Carlos Forero, Luis F. Gómez, Mercedes Mora-Plazas, María Parra-Murillo, María Parra-Murillo, Sara Toquica, Lindsey Smith Taillie

“…McNemar’s test for paired data was used to evaluate changes in the proportion of each of the critical nutrients and NNS to be regulated.ResultsThere were no significant changes in sodium, saturated fat, trans fat, or free sugar in foods or beverages prior to policy implementation. …”
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Shear bond strength of three different fixed retainers: Stainless steel wires versus fiber reinforced composite (An in Vitro study) by Anees Mahmood Mudhir

“…Methods: One‐hundred twenty extracted human upper premolar teeth (60 pairs) were divided into three groups(40 for each group) bonded with three different types of retainer wires (db Straight‐8strand flattened nickel free braided wire 0.028 x 0.008 inches UK, 3M 0.0175; multi‐stranded wire and Speed korean orthodontic fiber reinforced splint (2 mm x 200 mm ‐ FS‐2) which were bonded to the lingual surface of the teeth as fixed retainers by specific adhesives (Transbond LR, 3M). …”
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LINE-1 methylation status and survival outcomes in colorectal cancer patients: A systematic review and meta-analysis by Akbar Bagheri, Tohid Jafari-Koshki, Leila Alizadeh, Mortaza Raeisi, Yaghoub Moaddab, Abbas Karimi

“…Relevant studies were identified through systematic database searches, and summary hazard ratios (HRs) with 95 % confidence intervals (CIs) were calculated for relations between LINE-1 hypomethylation and overall survival (OS), disease-free survival (DFS), and cancer-specific survival (CSS). …”
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Venetoclax added to CLAG regimen might improve the outcome of patients with relapsed/refractory acute myeloid leukemia by Yu Zhang, Zhao Yin, Zurong Yao, Dan Xu, Xuejie Jiang, Xiaqi Nie, Dandan Chen, Hongsheng Zhou, Pengcheng Shi, Hui Liu, Qifa Liu, Guopan Yu

“…The endpoints of this study were to evaluate the rate of composite complete remission (CRc), measurable residual disease (MRD), event-free survival (EFS), overall survival (OS), and relapse between CLAG and CLAG + Ven groups. …”
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Estimating Complex Signals With a Fuzzy-Enhanced Kalman Filter: A Note on “the Output Regulation and the Kalman Filter as the Signal Generator” by Jesus Alberto Meda-Campana, Juan Carlos Garcia-Hernandez, Rodolfo Daniel Velazquez-Sanchez, Luis Alberto Paramo-Carranza, Tonatiuh Hernandez-Cortes, Ricardo Tapia-Herrera

“…To overcome this problem, this paper proposes a solution for estimating complex, unmodeled, and noise-contaminated signals while simultaneously obtaining a low-dimensional dynamical model whose output approximates the actual noise-free signal. This is achieved by incorporating a fuzzy error covariance matrix into the standard linear Kalman filter algorithm. …”
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A soft tick vector of Babesia sp. YLG in Yellow-legged gull (Larus michahellis) nests by Bonsergent, Claire, Vittecoq, Marion, Leray, Carole, Jouglin, Maggy, Buysse, Marie, McCoy, Karen D., Malandrin, Laurence

“…YLG DNA in several male testes and in endospermatophores, and notably in a parasite-free female (uninfected ovaries and salivary glands), raise the interesting possibility of sexual transmission from infected males to uninfected females. …”
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