Perspectives of substance use disorder counselors on the benefits and drawbacks of medications for opioid use disorder by Nicholas C. Cardamone, Rebecca E. Stewart, Kyle M. Kampman, Steven C. Marcus

“…Counselors were asked to describe, in a free-response format, the most important advantages and disadvantages to communicate to their clients about taking buprenorphine, methadone, and naltrexone. …”
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BRAF mutant appendiceal adenocarcinoma differs from colorectal cancer but responds to BRAF-targeted therapy by Vinay K. Pattalachinti, Emaan Haque, Mahmoud Yousef, Abdelrahman Yousef, Saikat Chowdhury, Michael Overman, Christine M. Parseghian, Van K. Morris, Bryan Kee, Ryan W. Huey, Kanwal Raghav, Colin M. Court, John Paul Shen

“…BRAFV600E + EGFR inhibition shows efficacy in BRAF V600E AA (disease control rate = 80%, median progression-free survival = 7.1 months).…”
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Flexible and cost-effective deep learning for accelerated multi-parametric relaxometry using phase-cycled bSSFP by Florian Birk, Lucas Mahler, Julius Steiglechner, Qi Wang, Klaus Scheffler, Rahel Heule

“…In this study, feed-forward deep neural network (DNN)- and iterative fitting-based frameworks are compared for multi-parametric (MP) relaxometry based on phase-cycled balanced steady-state free precession (pc-bSSFP) imaging. The performance of supervised DNNs (SVNN), self-supervised physics-informed DNNs (PINN), and an iterative fitting framework termed motion-insensitive rapid configuration relaxometry (MIRACLE) was evaluated in silico and in vivo in brain tissue of healthy subjects, including Monte Carlo sampling to simulate noise. …”
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Association of blood pressure and left ventricular mass with subclinical coronary atherosclerosis by Weiting Huang, Calvin Chin, Rehena Sultana, Chirk Jenn Ng, Jonathan Jiunn Liang Yap, Enver De Wei Loh, Swee Yaw Tan, Siew Ching Kong, Khung K Yeo

“…This study aimed to evaluate the risk factors associated with LV mass and subclinical coronary atherosclerosis, in an Asian population free of baseline cardiovascular disease.Methods The SingHEART study is a population-based cohort in which individuals underwent ambulatory blood pressure (BP) monitoring, cardiac MRI to measure indexed LV mass index (LVMI) and coronary artery calcium (CAC) scoring. …”
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The impact of PD-L1 expression status on the prognosis of ALK-positive lung cancer patients by Li Wang, Yingjun Kong, Yao Zhang, Chuanyong Mu

“…PD-L1 positive patients were predominantly male, over 55 years old, and presented more clinical symptoms, higher Ki-67 expression, larger tumor sizes, and more advanced disease stages. The progression-free survival (PFS) and overall survival (OS) were significantly lower in the ALK+PD-L1+ group compared to the ALK+PD-L1- group. …”
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Methods for identifying adverse drug reactions in primary care: A systematic review. by Vera Logan, David Hughes, Adam Turner, Neil Carter, Sue Jordan

“…<h4>Methods</h4>A systematic search was conducted in Medline, CINAHL, Scopus, Web of Science and Cochrane library, using controlled vocabulary (MeSH) and free-text terms. Randomised controlled trials (RCTs) implementing strategies to identify or resolve ADRs experienced by patients in primary care were included. …”
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Design and Fabrication of a Car Sports Rims. by Nsimbe Laban

“…In this study, all the stresses that act on the car rim and other requirements that must be met by the car rim were determined using design equations and free body diagrams. The rim components capable of withstanding these stresses were sized and drafted using solid works 2020. …”
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Factors Associated with Male Partner Support During Pregnancy and Child Birth in Kabale District. by Niwarinda, Denesi

“…Background: Pregnancy and child births are natural processes but by no means risk-free. Efforts to improve maternal and child’s health services have been made, but poor outcomes of pregnancy and child’s birth remain high in Sub Saharan Africa. …”
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Creative Marketing and Financial Performance of Small Medium Enterprises in Rwanda: A Case Study of Selected Businesses in Nyamata Town. by Tenywa, Bashir

“…The results revealed that timing and credit terms has a positive and statistically significant influence on financial literacy (β =.821: p = .003) which indicates that emphasizing financial literacy through setting aside funds and handling debt will increase one's capacity to start small businesses independently, increase the purchasing power of personal belongings, be able to manage debts, be free to make financial decisions, raise one's standard of living, be able to access health and other services, and be able to take on leadership roles. …”
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Factors Associated with Male Partner Support During Pregnancy and Child Birth in Kabale District. by Niwarinda, Denesi

“…Background: Pregnancy and child births are natural processes but by no means risk-free. Efforts to improve maternal and child’s health services have been made, but poor outcomes of pregnancy and child’s birth remain high in Sub Saharan Africa. …”
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The Effect of Banana Bacteria Wilt on the Socio-Economic Welfare of Farmers in Ruhinda Sub-County Rukungiri District by Tayebwa, Rameka

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The Effect of Banana Bacteria Wilt on the Socio-Economic Welfare of Farmers in Ruhinda Sub-County Rukungiri District by Tayebwa, Rameka

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Compound events in Germany in 2018: drivers and case studies by E. Xoplaki, E. Xoplaki, F. Ellsäßer, F. Ellsäßer, J. Grieger, K. M. Nissen, J. G. Pinto, M. Augenstein, T.-C. Chen, T.-C. Chen, H. Feldmann, P. Friederichs, D. Gliksman, D. Gliksman, L. Goulier, K. Haustein, K. Haustein, J. Heinke, L. Jach, F. Knutzen, S. Kollet, J. Luterbacher, J. Luterbacher, N. Luther, S. Mohr, S. Mohr, C. Mudersbach, C. Müller, E. Rousi, F. Simon, L. Suarez-Gutierrez, L. Suarez-Gutierrez, L. Suarez-Gutierrez, S. Szemkus, S. M. Vallejo-Bernal, S. M. Vallejo-Bernal, S. M. Vallejo-Bernal, O. Vlachopoulos, F. Wolf

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The combination of a tyrosine kinase inhibitor and blinatumomab in patients with Philadelphia chromosome–positive acute lymphoblastic leukemia or Philadelphia chromosome‐like acute... by Xiaoxia Wu, Shenqi Lu, Xinhui Zhang, Zhen Yang, Aining Sun, Depei Wu, Huifen Zhou, Miao Miao

“…The combination of blinatumomab and a TKI in the frontline setting has shown the safety and efficacy of the chemotherapy‐free treatment approach in patients with Ph + ALL. …”
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Impact of corticosteroids on the efficacy of first-line pembrolizumab plus chemotherapy in patients with advanced non-small-cell lung cancer by Amytis Roboubi, Eric Wasielewski, Soraya Bordier, Amélie Turlotte, Geoffrey Pavaut, Arnaud Scherpereel, Alexis Cortot, Clément Gauvain

“…Methods: The primary endpoint was progression-free survival (PFS) according to SC exposure status (⩾10 mg/day), adjusted in a multivariate Cox model for the following confounders: age, performance status, hospital admission prior to treatment, number of metastatic sites, brain metastases, bone metastases, PD-L1 status, and histological subtype. …”
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Satisfaction with a daily supportive text messaging program aimed at promoting psychological well-being of educators: Outcomes from implementation of the Wellness4Teachers by Belinda Agyapong, Pamela Brett-MacLean, Raquel da Luz Dias, Yifeng Wei, Vincent Israel Opoku Agyapong

“…Data was collected from educators who self-subscribed to the free Wellness4Teachers program in Canada. Participants’ satisfaction levels were assessed using a Likert scale to evaluate the responses to different aspects of the program. …”
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Long-term Conservative Follow-up in Children with High-grade Vesicoureteral Reflux and an Abnormal Dimercaptosuccinic Acid Scan by Pankaj V Deshpande

“…A total of 59 children (39 boys and 20 girls) (72%) had MCUG done after UTI while 20 (19 boys and one girl) (24%) children had it done for antenatal hydronephrosis (four of whom had developed UTI immediately after MCUG but had remained free of UTIs thereafter). Conclusion: Conservative management of high-grade VUR, either unilateral or bilateral, in children with an abnormal DMSA does not lead to recurrent severe UTIs. …”
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Comprehensive Review of Wearable Antennas With Flexible Periodic Structures for Body-Effect Mitigation by Adel Ashyap, Raad Raad, Faisel Tubbal, Wajid Ali Khan, Suhila Abulgasem

“…Furthermore, this study provides an in-depth review of 81 papers evaluating the performance of antennas integrated with periodic structures, both in free space and on the human body, across single-band, dual-band, and triple-band designs. …”
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On the behavior of a granular soil deposit subjected to horizontal vibration. A discrete element modeling by Derbane, Said, Mansouri, Mouloud, Messast, Salah,  El Malki Alaoui, Aboulghit

“…The analysis particularly focused on the amplification of the movement at the free surface of the deposit, as well as its dependence on some parameters such as the excitation frequency and the excitation amplitude of the deposit confinement. …”
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Improvement of the dissolution of the antineoplastic drug regorafenib through impregnation into pullulan polysaccharide using supercritical fluid technology: Optimization of the pr... by Ali Sheikhi, Sepideh Hamedi, Gholamhossein Sodeifian, Fariba Razmimanesh

“…The dissolution rate of the impregnated REG MH in an aqueous medium considerably enhanced to 80 % during 60 h, whereas it reached 18 % for the free drug. The drug release from the polymer matrix is predominantly controlled by the Fickian diffusion mechanism.…”
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