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  1. 4521

    Intelligent diagnosis and prediction of pregnancy induced hypertension in obstetrics and gynecology teaching by integrating GA by Xiaolan Li, Xiaolan Li, Xiaolan Li, Fen Kang, Fen Kang, Fen Kang, Xiaojing Li, Xiaojing Li, Xiaojing Li

    Published 2025-02-01
    “…The objective of this model is to maximize the utility of medical data and enhance treatment quality.ResultsThe refined intelligent feature selection approach identified several significant indicators of pregnancy-related hypertension, such as phosphor dehydrogenase deficiency, body mass index, gestational urinary proteins, vascular endothelial growth factor receptor 1, placental growth factor, thalassemia, and a familial history of diabetes mellitus or hypertension. …”
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  2. 4522

    Developing a new clinical governance framework for chronic diseases in primary care: an umbrella review by Walter Ricciardi, Gianfranco Damiani, Alessandra Buja, Vincenzo Baldo, Mark H Ebell, Roberto Toffanin, Mirko Claus

    Published 2018-07-01
    “…Interventions for patients and their families should focus on their values; on clinical, professional and institutional integration and finally on accountability to patients, peers and society at large. …”
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  3. 4523

    Protocol for the implementation evaluation of an integrated paediatric and primary care model: Strengthening Care for Children (SC4C) by Yvonne Zurynski, Susan Woolfenden, Peter D Hibbert, Harriet Hiscock, Raghu Lingam, Karen Wheeler, Michael Hodgins, Jade Burley, Rachel Pelly, Jane Le, Sonia Khano, Tammy Meyers Morris, Stephanie Germano

    Published 2022-09-01
    “…Data collection will be via questionnaires and semistructured interviews with general practitioners, paediatricians, general practice administrative staff and children and families. Each of the 21 general practices recruited into the study will be described in terms of staffing, patient throughput and location, in addition to the nuanced inner and outer contexts, use of the intervention and its acceptability. …”
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  4. 4524

    Effect of cubebin against streptozotocin-induced diabetic nephropathy rats via inhibition TNF-α/NF-κB/TGF-β: in vivo and in silico study by Rahamat Unissa Syed, Sivakumar S. Moni, Weiam Hussein, Taghreed Mohammad Saad Alhaidan, Sondos Mohammed Y. Abumilha, Lama Khalid Alnahdi, Ling Shing Wong, Vetriselvan Subramaniyan, Vinoth Kumarasamy

    Published 2025-02-01
    “…Abstract Cubebin, a dibenzyl butyrolactone lignan belonging to several distinct families, including Aristolochiaceae, Myristicaceae, Piperaceae, and Rutaceae, and possesses several pharmacological activities, including analgesic, anti-inflammatory, antioxidant, and vasodilatory. …”
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  5. 4525

    Cardiovascular Disease and Its Implication for Higher Catastrophic Health Expenditures Among Households in Sub-Saharan Africa by Folashayo Ikenna Peter Adeniji, Taiwo Akinyode Obembe

    Published 2023-03-01
    “…Like many chronic health conditions, CVD predisposes families to catastrophic health expenditure (CHE), especially in SSA due to the low health insurance coverage. …”
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  6. 4526
  7. 4527

    The refugees and health crisis: migration policy management and government response to Afghan migrants by Kalsoom B. Sumra, Muhammad Mumtaz, Naqib Ullah Khan, Helen Huifen Cai, Qiong Yuan

    Published 2025-02-01
    “…Methods The proposed model is tested with 427 Afghan refugees’ families from five major cities of Pakistan. The partial least squares structural equation modelling (PLS-SEM) is used to test the vulnerability significance with the crisis and government response in facilities. …”
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  8. 4528

    The emerging role of glycine receptor α2 subunit defects in neurodevelopmental disorders by Sean D. Fraser, Sean D. Fraser, Robert J. Harvey, Robert J. Harvey

    Published 2025-02-01
    “…Rare neurodevelopmental disorders (NDDs) are one of the most significant unmet challenges in healthcare due to their lifelong nature, high management costs, and recurrence within families. This review will focus on newly-emerging genetic forms of NDDs resulting from variants in the glycine receptor (GlyR) α2 subunit gene. …”
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  9. 4529

    Alzheimer-mutant γ-secretase complexes stall amyloid β-peptide production by Parnian Arafi, Sujan Devkota, Emily Williams, Masato Maesako, Michael S Wolfe

    Published 2025-02-01
    “…Missense mutations in the amyloid precursor protein (APP) and presenilin-1 (PSEN1) cause early-onset familial Alzheimer’s disease (FAD) and alter proteolytic production of secreted 38-to-43-residue amyloid β-peptides (Aβ) by the PSEN1-containing γ-secretase complex, ostensibly supporting the amyloid hypothesis of pathogenesis. …”
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  10. 4530

    Cost-Effectiveness of the Prenatal Detection of Congenital Heart Diseases: A Systematic Literature Review by Darío Londoño Trujillo, Paula A. Castro García, Kristian K. Rojas López, Karen J. Moreno-Medina, María T. Dominguez Torres, Rodolfo J. Dennis Verano, Nestor F. Sandoval Reyes

    Published 2024-05-01
    “…This significant health and economic burden on healthcare systems and families highlights the relevance of evaluating the cost-effectiveness of methods for early detection of this condition. …”
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  11. 4531

    Clinical and Cost Burden of Primary Sjögren’s Syndrome: Descriptive Analysis Using a US Administrative Claims Database by Sue Perera, Liyuan Ma, Raj Punwaney, Sulabha Ramachandran

    Published 2018-02-01
    “…We report descriptive data from employees and their families, as covered by employer-sponsored medical insurance. …”
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  12. 4532

    Prevalence and Associated Risk Factors of Childhood Obesity and Overweight in Erbil City, Kurdistan, Iraq: A Household Survey by Sabah Shareef Mohammed, Sherzad Abdulahad Shabu

    Published 2024-03-01
    “…According to these results, families have to improve their lifestyles and decrease the use of electrical devices by children. …”
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  13. 4533

    New aspects of investigating stress, anxiety, and depression in the Ryazan region population with arterial hypertension by Ayoub Glenza, Natalia V. Dobrynina, Sergey S. Yakushin, Alexander A. Dzekan

    Published 2024-12-01
    “…Lonely people have higher levels of stress 16 (12–20), anxiety 6 (4–9), and depression 6 (3–9) compared to those living with their families (р=0.004, р=0.026, and р 0.001, respectively). …”
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  14. 4534

    Delayed Postoperative Ambulation Results in a Significant Increase in 90-Day Mortality in Surgically Treated Hip Fractures by Robert S. Wood DO, Maddie Vergun BS, Elizabeth Herrera MPH, Jacqueline Krumrey MD

    Published 2025-12-01
    “…Introduction Hip fractures in individuals aged 65 and older present a significant burden to patients, families, and health care systems. These fractures lead to increased morbidity, loss of autonomy in Activities of Daily Living (ADLs), prolonged hospitalization, and heightened mortality rates. …”
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  15. 4535

    Writers, readers, and erasers of N6-Methyladenosine (m6A) methylomes in oilseed rape: identification, molecular evolution, and expression profiling by Chaofan Shan, Kui Dong, Dongyu Wen, Ziyi Ye, Fei Hu, Meryem Zekraoui, Jun Cao

    Published 2025-02-01
    “…During the course of evolution, whole genome duplication (WGD) and segmental duplication were the primary drivers of the expansion of m6A-related gene families. The genes were subjected to rigorous purification selection. …”
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  16. 4536

    Interplay between fecundity, sexual and growth selection on the spring phenology of European beech (Fagus sylvatica L.). by Oddou-Muratorio, Sylvie, Bontemps, Aurore, Gauzere, Julie, Klein, Etienne K

    Published 2024-03-01
    “…Morever, TBB and growth were surveyed in 3261 seedlings from 40 families grown planted in a common garden, and viability selection was inferred by regressing growth on TBB. …”
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  17. 4537

    Atypical early neural responses to native and non-native language in infants at high likelihood for developing autism by Lauren Wagner, Megan Banchik, Tawny Tsang, Nana J. Okada, Rebecca Altshuler, Nicole McDonald, Susan Y. Bookheimer, Shafali S. Jeste, Shulamite Green, Mirella Dapretto

    Published 2025-02-01
    “…Methods In this study, we used functional magnetic resonance imaging (fMRI) to examine differences in language processing in 9-month-old infants at high (HL) and typical (TL) familial likelihood for ASD. Infants were presented with native (English) and novel (Japanese) speech while sleeping naturally in the scanner. …”
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  18. 4538

    Unveiling inequalities: Racial, ethnic, and socioeconomic disparities in diabetes: Findings from the 2007-2020 NHANES data among U.S. adults by Yangyang Deng, Mohammad Moniruzzaman, Breanna Rogers, Lu Hu, Ram Jagannathan, Kosuke Tamura

    Published 2025-02-01
    “…Males among non-Hispanic Black, Hispanic, and other adults and females from low and middle-SES families had a higher prevalence of diabetes. Conclusion: Minority groups, middle and older-aged adults, males from minority groups, and females from low SES had a greater prevalence of diabetes. …”
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  19. 4539

    Evaluation of variation in special educational needs provision and its impact on health and education using administrative records for England: umbrella protocol for a mixed-method... by Stuart Logan, Ruth Gilbert, Tamsin Ford, Johnny Downs, Jugnoo Rahi, Ania Zylbersztejn, Katie Harron, Kate Boddy, Bianca De Stavola, Vincent Nguyen, Isaac Winterburn, Kate Lewis, Lucy Karwatowska, Lorraine Dearden, Sarah Barnes, Jacob Matthews, Matthew Lilliman, Jennifer Saxton, Antony Stone, Kristine Black-Hawkins

    Published 2023-11-01
    “…Triangulation of findings on outcomes, variation and impact of SEN provision for different health phenotypes in ECHILD, with experiences of SEN provision will inform interpretation of findings for policy, practice and families and methods for future evaluation.Ethics and dissemination Research ethics committees have approved the use of the ECHILD database and, separately, the survey, interviews and focus groups of young people, parents and service providers. …”
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  20. 4540

    Higher gut Bacteroidetes and Actinobacteria population in early pregnancy is associated with lower risk of gestational diabetes in the second trimester by Seyedeh Neda Mousavi, Navid Momeni, Hossein Chiti, Howra Mahmoodnasab, Mohammad Ahmadi, Siamak Heidarzadeh

    Published 2025-02-01
    “…Controls (N = 60) were selected from non-GDM participants matching to the GDM in terms of pre-pregnancy weight, weight gain, dietary intake and familial history of diabetes. The dominant phylum population was determined based on 16SrRNA gene expression. …”
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