Exploring the drivers of adolescent sexual and reproductive healthcare-seeking behavior in northwestern Botswana: a cross-sectional analysis by Mackenzie Lawson, Helen Apps, Peggie Ramaphane, Francis Barchi

“…Teachers (31%) and female family members (31%) were the most frequently consulted sources on bodily changes during adolescence. …”
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Exploring BCL2 regulation and upstream signaling transduction in venetoclax resistance in multiple myeloma: potential avenues for therapeutic intervention by Rodrigo Fonseca, Yuan Xiao Zhu, Laura A. Bruins, Joseph Ahmann, Cecilia de Bonolo Campos, Esteban Braggio, Xianfeng Chen, Mariano Arribas, Susie Darvish, Seth Welsh, Erin Meermeier, Kiran K. Mangalaparthi, Richard K. Kandasamy, Greg Ahmann, J. Erin Wiedmeier-Nutor, Akhilesh Pandey, Marta Chesi, P. Leif Bergsagel, Rafael Fonseca

“…Transcriptomic and proteomic analysis revealed that resistance was largely associated with BCL-2 family protein dysregulation, including upregulation of anti-apoptotic proteins such as MCL-1, BCL-XL, BCL-2, and downregulation of pro-apoptotic members. …”
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Real-World Health Care Outcomes and Costs Among Patients With Juvenile Idiopathic Arthritis in Spain by Jordi Antón, Estefania Moreno Ruzafa, Mireia Lopez Corbeto, Rosa Bou, Judith Sánchez Manubens, Sonia Carriquí Arenas, Joan Calzada Hernández, Violetta Bittermann, Carolina Estepa Guillén, Juan Mosquera Angarita, Lucía Rodríguez Díez, Estíbaliz Iglesias, Miguel Marti Masanet, Berta Lopez Montesinos, Maria I. González Fernández, Alfonso de Lossada, Carmen Peral, Mónica Valderrama, Noelia Llevat, María Montoro Álvarez, Immaculada Calvo Penadés

“…Indirect JIA cost per family was €747.20 (€1452.80). **Conclusion:** JIA causes significant costs to the Spanish healthcare system and affected families. …”
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Epidemiological Study of Hepatitis B, C and HIV Cases among the Foreigners Visiting Sulaimani City from 2013 Through 2016 by Mohammed Omer Mohammed, Asan Baram Hasan, Fenk Bakir Maarouf

“…Dental procedures, surgery, blood transfusion and family history were common risk factors. HBV infection was highest among Syrian foreigners. …”
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Risk of suicide in a sample of Egyptian high school adolescent students: a cross-sectional study by Eman S. Rabie, Marwa Soltan, Hanan Elrassas, Atteya Khairy, Moatazbellah I. Ali

“…While positive personal history of suicidal attempts, positive psychiatric illnesses and positive family history of suicide showed a significant correlated (P ≤ 0.05) with larger Suicide Probability Scale scores. …”
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Protocol on a systematic review of nomenclature and outcomes in children with complex critical illness in Paediatric Critical Care: The basis for consensus definition. by Sofia Cuevas-Asturias, Claire Rafferty, Hannah Mitchell, William Tremlett, Padmanabhan Ramnarayan, Natalie Pattison

“…Children with complex critical illness (CCI) need input from multiple different teams alongside support for their family. CCI often become prolonged PCC-stay patients too. …”
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Epidemiology of clinically significant migraine in Israel: a retrospective database study by A. Shifrin, E. Domany, M. Tirosh, D. Davidovici, S. Vinker, I. Forschner, A. Israel

“…Approximately two-thirds of new patients were diagnosed by neurologists, with only 19% diagnosed by family physicians. Compared to a matched control population, migraine patients showed a higher prevalence of low body mass index (BMI) and higher diastolic blood pressure (BP). …”
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Knowledge of mothers on diaper dermatitis management and associated factors in Ethiopia by Atoma Negera, Midekso Sento, Gemechu Tola

“…The study findings revealed that 84.6% of mothers had self-reported good knowledge of DD and its management, and their main source of information is family members and relatives (35.4%). Nearly two-thirds (65.4%) of children experienced DD, and only 23.6% sought healthcare. …”
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To remove or to replace traditional electronic games? A crossover randomised controlled trial on the impact of removing or replacing home access to electronic games on physical act... by Anne J Smith, Leon M Straker, Rebecca A Abbott

“…Objective To evaluate the impact of (1) the removal of home access to traditional electronic games or (2) their replacement with active input electronic games, on daily physical activity and sedentary behaviour in children aged 10–12 years.Design Crossover randomised controlled trial, over 6 months.Setting Family homes in metropolitan Perth, Australia from 2007 to 2010.Participants 10-year-old to 12-year-old children were recruited through school and community media. …”
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Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling by Jeonghyeon Kwon, Haruya Kawase, Kenny Mattonet, Stefan Guenther, Lisa Hahnefeld, Jamal Shamsara, Jan Heering, Michael Kurz, Sina Kirchhofer, Cornelius Krasel, Michaela Ulrich, Margherita Persechino, Sripriya Murthy, Cesare Orlandi, Christian D. Sadik, Gerd Geisslinger, Moritz Bünemann, Peter Kolb, Stefan Offermanns, Nina Wettschureck

“…Mechanistically, we found that GPRC5B physically interacts with GPCRs of the prostanoid receptor family, resulting in enhanced signaling through the prostaglandin E receptor 2 (EP2). …”
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Maternal and Neonatal Outcomes of Syrian Adolescent Refugees and Local Adolescent Turkish Citizens: A Comparative Study at a Tertiary Care Maternity Hospital in Türkiye by Ceren Golbasi, Tayfun Vural, Burak Bayraktar, Hakan Golbasi, Alkim Gulsah Sahingoz Yildirim

“…Immigrant women should be provided with fertility, family planning, and training on behavior that protects reproductive health. …”
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Influence of sacroiliac joint variation on clinical features of axial spondyloarthritis: a comparative analysis by Denis Poddubnyy, Torsten Diekhoff, Sevtap Tugce Ulas, Fabian Proft, Valeria Rios Rodriguez, Judith Rademacher, Juliane Greese, Katharina Ziegeler, Carolina Dominguez Aleixo, Maximilian Lindholz

“…Classification of back pain as inflammatory (=IBP), human leucocyte antigen-B27 positivity, family history, disease activity according to Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), symptom duration, elevated acute phase reactants, peripheral and extramusculoskeletal manifestations were evaluated. …”
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The financial toxicity of cancer: unveiling global burden and risk factors – a systematic review and meta-analysis by Addisu Getie, Alemu Birara Zemariam, Befkad Derese Tilahun, Ribka Nigatu Haile, Tegene Atamenta Kitaw, Molla Azmeraw Bizuayehu

“…Key risk factors included large family size, low income, lack of health insurance, longer disease duration, older age and multiple treatments. …”
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Microplastic exposure induces HSP90α secretion and aggravates asthmatic airway remodeling via PI3K-Akt-mTOR pathway by Mingming Xu, Jiyuan Chen, Lin Gao, Shaoxi Cai, Hangming Dong

“…Heat shock protein 90α(HSP90α) is one of cytokines involving in inflammation which is a member of the HSPs family. The aim of this study is to explore the mechanism by which microplastics influence the secretion of HSP90α and the progression of asthma. …”
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Pengembangan Knowledge Management System Ukiran Kayu Khas Bali Berbasis Artificial Intelligence by I Putu Restu Indrawan Prabawa, Ariq Cahya Wardhana

“…Hindu beliefs believe that the spirits of the family's ancestors inhabit sanggah, where they are placed in sacred corners or in empty areas of the house. …”
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Community perceptions of community health worker effectiveness: Contributions to health behaviour change in an urban health district in South Africa by L S Thomas, Y Pillay, E Buch

“…Their overall purpose is to improve access to healthcare and encourage healthy behaviour in vulnerable communities, through community and family engagements, leading to less disease and better population health. …”
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Exploring the antimicrobial and antioxidative potential of Leucas aspera (Willd.) link: Phytochemical screening, molecular docking, and HR-LC/MS profiling against SARS-CoV-2 protei... by Thavasiaanatham Seenivasan Shalini, Ragothaman Prathiviraj, Poomalai Senthilraja

“…Link, a member of the Lamiaceae family and commonly known as ''Thumbai,'' is found throughout India and has been utilized in traditional Indian medicine to treat various ailments. …”
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Medicinal plants used to treat human ailments in Wadla District, Northern Ethiopia: An ethnobotanical approach by Sara Yosef, Ermias Lulekal, Asfaw Debela, Muhidin Tahir

“…The Solanaceae family represented the greatest number of species (7 species). …”
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Defining patient-reported outcomes in diabetes, obesity, cardiovascular disease, and chronic kidney disease for clinical practice guidelines - perspectives of the taskforce of the... by Katharine Barnard-Kelly, Tadej Battelino, Frank C. Brosius, Antonio Ceriello, Francesco Cosentino, James R. Gavin, Francesco Giorgino, Jennifer Green, Linong Ji, Monika Kellerer, Sue Koob, Mikhail Kosiborod, Nebojsa Lalic, Nikolaus Marx, Prashant Nedungadi, Christopher G. Parkin, Helena W. Rodbard, René D. Rötzer, Lars Rydén, Wayne Huey-Herng Sheu, Eberhard Standl, Britta Tendal Jeppesen, Pinar Topsever, Per Olav Vandvik, Christoph Wanner, Oliver Schnell

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Community Caregivers’ Perspectives on Health IT Use for Children With Medical Complexity: Qualitative Interview Study by Farah Elkourdi, Onur Asan

“…They are often the first point of contact for the families of children with medical complexity, particularly in vulnerable communities, including families in rural areas, low-income households, and non–English-speaking immigrant populations. …”
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