-
1
Executioner caspase is proximal to Fasciclin 3 which facilitates non-lethal activation in Drosophila olfactory receptor neurons
Published 2025-06-01“…Here, we analyzed proximal proteins of Drosophila executioner caspase in the adult brain using TurboID. …”
Get full text
Article -
2
La représentation du chien dans le roman policier francophone : compagnon, enquêteur, victime ou bourreau ?
Published 2020-01-01Subjects: Get full text
Article -
3
-
4
Akt1 and dCIZ1 promote cell survival from apoptotic caspase activation during regeneration and oncogenic overgrowth
Published 2020-11-01“…Abstract Apoptosis is an ancient and evolutionarily conserved cell suicide program. During apoptosis, executioner caspase enzyme activation has been considered a point of no return. …”
Get full text
Article -
5
Semiotyka twarzy kata i ofiary
Published 2016-10-01“…Drawing on classics of Polish and world cinema, and also on the memory of culture, Marek Hendrykowskis study contains a semiotic analysis of the deep structures of images, which present the executioner-victim based on violence executioner as a variant of inter-human relations in totalitarian systems. …”
Get full text
Article -
6
Mitochondria: Regulators of Cell Death and Survival
Published 2002-01-01“…The present review attempts to outline the complex milieu of events regulating the mitochondrial commitment to and processes involved in the implementation of the executioner phase of apoptotic cell death.…”
Get full text
Article -
7
L’Angleterre et l’Écosse au miroir de la fureur : L’Écossaise d’Antoine de Montchrestien et Marie Stuard de Charles Regnault
Published 2022-01-01“…Lastly, the issues at stake are of a hagiographic nature, as French playwrights celebrated the Catholic Queen as the innocent victim of the executioner that Elizabeth I had become.…”
Get full text
Article -
8
Distinct developmental and degenerative functions of SARM1 require NAD+ hydrolase activity.
Published 2022-06-01“…SARM1 is the founding member of the TIR-domain family of NAD+ hydrolases and the central executioner of pathological axon degeneration. SARM1-dependent degeneration requires NAD+ hydrolysis. …”
Get full text
Article -
9
FROM PAIN TO DELIGHT IN THE LEGEND ABOUT ST. ELIZABETH (COMPLEMENTARITY AND CONTRAST)
Published 2023-11-01“…The author of the legend does not intentionally express the erotic and sexual preferences of the main character Elizabeth as a passive sufferer of pain, nor the character of master Conrad as an active executioner of punishments. Relevant events are described in the language of that time, which did not contain the means to name the sexual practices known in the culture of today. …”
Get full text
Article -
10
The 19 kDa Mycobacterium tuberculosis Lipoprotein (LpqH) Induces Macrophage Apoptosis through Extrinsic and Intrinsic Pathways: A Role for the Mitochondrial Apoptosis-Inducing Fact...
Published 2012-01-01“…LpqH triggered TLR2 activation, with upregulation of death receptors and ligands, which was followed by a death receptor signaling cascade with activation of initiator caspase 8 and executioner caspase 3. In this caspase-mediated phase, mitochondrial factors were involved in loss of mitochondrial transmembrane potential (ΔΨm), release of cytochrome c, and caspase 9 activation. …”
Get full text
Article -
11
The Lynching of Witches in Northern Ghana
Published 2024-04-01“…In this act, the issue of the victims’ status is most often secondary, since the mob acts as a prosecutor, judge, jury, and executioner. Thus, employing a feminist public theological perspective, this study interrogates the traditional institution of witch camps and the accusation of women being witches in northern Ghana. …”
Get full text
Article -
12
CasExpress reveals widespread and diverse patterns of cell survival of caspase-3 activation during development in vivo
Published 2016-04-01“…Caspase-3 carries out the executioner phase of apoptosis, however under special circumstances, cells can survive its activity. …”
Get full text
Article -
13
EVOLUTION OF THE JURIDICAL REGULATION REGARDING THE PENITENTIARY ADMINISTRATION IN ROMANIA
Published 2012-05-01“…To deeply analyze the evolution of the regulation regarding the penitentiary administration, one has to make an incursion into the straight modalities of the executioner punishment but also to well know the conditions, treatment and modality of the execution of the punishment in prisons all together with the obvious purpose of maintaining our citizens’ safety. …”
Get full text
Article -
14
Bcl-2-mediated control of TRAIL-induced apoptotic response in the non-small lung cancer cell line NCI-H460 is effective at late caspase processing steps.
Published 2018-01-01“…Notably, especially the final cleavage steps of the initiator caspase-8 and the executioner caspase-3 were effectively blocked by Bcl-2 overexpression. …”
Get full text
Article -
15
LYSOSOME-DEPENDENT CELL DEATH DEFINES SPECIFIC ENDOTHELIAL TOXICITY OF CALCIUM PHOSPHATE BIONS
Published 2019-09-01“…Upon internalization by endothelial cells, CPB cause their death due to dissolution in lysosomes and subsequent release of calcium ions into the cytosol, ultimately leading to cleavage of executioner caspases. MPB lack endothelial toxicity because their dissolution does not lead to release of calcium ions. …”
Get full text
Article -
16
Programmed neurite degeneration in human central nervous system neurons driven by changes in NAD+ metabolism
Published 2025-01-01“…Since neither ferroptosis nor necroptosis, nor caspase-dependent apoptosis seemed to be involved in neurite loss, we investigated SARM1 as potential executioner (or controller). Knock-down or expression of a dominant-negative isoform of SARM1 indeed drastically delayed ND. …”
Get full text
Article -
17
Suppressing phagocyte activation by overexpressing the phosphatidylserine lipase ABHD12 preserves sarmopathic nerves
Published 2025-06-01“…In healthy axons, NMNAT2 inhibits SARM1, the key executioner of AxD, to keep it from depleting NAD+ and triggering axon destruction. …”
Get full text
Article -
18
Alterations of the interactome of Bcl-2 proteins in breast cancer at the transcriptional, mutational and structural level.
Published 2019-12-01“…In response to intracellular stress, the apoptotic balance is governed by interactions of three distinct subgroups of proteins; the activator/sensitizer BH3 (Bcl-2 homology 3)-only proteins, the pro-survival, and the pro-apoptotic executioner proteins. Changes in expression levels, stability, and functional impairment of pro-survival proteins can lead to an imbalance in tissue homeostasis. …”
Get full text
Article -
19
Gasdermin D is activated but does not drive neurodegeneration in SOD1G93A model of ALS: Implications for targeting pyroptosis
Published 2025-10-01“…While pyroptosis, an inflammatory form of programmed cell death, has been implicated in ALS, the specific role of Gasdermin D (GSDMD) - the primary executioner of pyroptosis – remains unexplored. In this study, we examined the function of GSDMD in the well-established SOD1G93A mouse model of ALS. …”
Get full text
Article -
20
Diverse cell types establish a pathogenic immune environment in peripheral neuropathy
Published 2025-05-01“…We identified a key pathogenic function of macrophages in a mouse model of a rare human congenital neuropathy in which SARM1, the central executioner of axon degeneration, is activated by hypomorphic mutations in the axon survival factor NMNAT2. …”
Get full text
Article