Showing 81 - 100 results of 151 for search '"evolutionary biology"', query time: 0.06s Refine Results
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    Natural selection and evolution: evolving concepts by Andre J. van Wijnen, Eric Lewallen

    Published 2024-05-01
    “… Many recent studies in evolutionary biology have expanded and refined definitions of biological evolution and natural selection. …”
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    A continuous phenotype space model of RNA virus evolution within a host by Andrei Korobeinikov, Conor Dempsey

    Published 2014-02-01
    “…Due to their very high replication and mutation rates, RNA virusescan serve as an excellent testing model for verifying hypothesis andaddressing questions in evolutionary biology.In this paper, we suggest a simple deterministic mathematical modelof the within-host viral dynamics, where a possibility for random mutations incorporates.This model assumes a continuous distribution of viral strainsin a one-dimensional phenotype space where random mutations aremodelled by Brownian motion (that is, by diffusion).Numerical simulations show that randommutations combined with competition for a resource result in evolutiontowards higher Darwinian fitness: a stable pulse traveling waveof evolution, moving towards higher levels of fitness,is formed in the phenotype space.The advantage of this model, compared with the previously constructedmodels, is that this model is mechanistic and is based on commonlyaccepted model of virus dynamics within a host, and thus it allowsan incorporation of features of the real-life host-virus system such as immuneresponse, antiviral therapy, etc.…”
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    PPARγ Signaling Mediates the Evolution, Development, Homeostasis, and Repair of the Lung by Virender K. Rehan, John S. Torday

    Published 2012-01-01
    “…By exploiting such deep cell-molecular functional homologies as targets for leveraging lung homeostasis, we have discovered that we can effectively prevent and/or reverse the deleterious effects of these pathogenic agents, demonstrating the utility of evolutionary biology for the prevention and treatment of chronic lung disease. …”
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