Intricate interplay of CRISPR-Cas systems, anti-CRISPR proteins, and antimicrobial resistance genes in a globally successful multi-drug resistant Klebsiella pneumoniae clone by Jianping Jiang, Astrid V. Cienfuegos-Galletd, Tengfei Long, Gisele Peirano, Tingyu Chu, Johann D. D. Pitout, Barry N. Kreiswirth, Liang Chen

“…Conclusions Our results indicated a complex interplay between CRISPR-Cas, anti-CRISPR, and mobile genetic elements that shape the evolution of CG147. Our findings advance the understanding of multi-drug resistance mechanisms and will aid in preventing the emergence of future MDR clones.…”
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Petrophysical Characterization and Gas Accumulation of Wufeng-Longmaxi Shale Reservoir in Eastern Margin of Sichuan Basin, SW China by Wei Wang, Dahua Li, Lijun Cheng, Ye Zhang, Jinxi Wang, Zhiping Zhang, Hualian Zhang, Dongxin Guo, Yuelei Zhang, Qing Hua, Jun Liu

“…Besides, the organic matter indicates the WL shale has a decent hydrocarbon generation ability, and the thermal evolution degree is also conducive to the full generation of shale gas. …”
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Ceria nanoparticles ameliorate renal fibrosis by modulating the balance between oxidative phosphorylation and aerobic glycolysis by Mengling Wang, Feng Zeng, Fengling Ning, Yinhang Wang, Shilin Zhou, Jiaqi He, Cong Li, Cong Wang, Xiaolin Sun, Dongliang Zhang, Jisheng Xiao, Ping Hu, Svetlana Reilly, Hong Xin, Xudong Xu, Xuemei Zhang

“…Unfortunately, the pathogenesis of renal fibrosis remains largely unexplored, among which metabolic reprogramming plays an extremely crucial role in the evolution of renal fibrosis. Ceria nanoparticles (CeNP-PEG) with strong ROS scavenging and anti-inflammatory activities have been applied for mitochondrial oxidative stress and inflammatory diseases. …”
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AI Chatbots and Cognitive Control: Enhancing Executive Functions Through Chatbot Interactions: A Systematic Review by Pantelis Pergantis, Victoria Bamicha, Charalampos Skianis, Athanasios Drigas

“…<b>Background/Objectives</b>: The evolution of digital technology enhances the broadening of a person’s intellectual growth. …”
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On the nascent wind of oxygen-rich AGB stars: scrutiny of a sample of nearby stars by Darriulat, Pierre, Hoai, Do Thi, Nhung, Pham Thi Tuyet, Diep, Pham Ngoc, Ngoc, Nguyen Bich, Thai, Tran Thi, Anh, Pham Tuan

“…We argue that the presence of stellar or planetary companions does not seriously impact the formation of the nascent wind and only modifies its subsequent evolution.…”
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PET-Assessed Metabolic Tumor Volume Across the Spectrum of Solid-Organ Malignancies: A Review of the Literature by Anusha Agarwal, Chase J. Wehrle, Sangeeta Satish, Paresh Mahajan, Suneel Kamath, Shlomo Koyfman, Wen Wee Ma, Maureen Linganna, Jamak Modaresi Esfeh, Charles Miller, David C. H. Kwon, Andrea Schlegel, Federico Aucejo

“…In the past few decades, the rapid evolution of imaging modalities has shifted the paradigm towards image-based precision medicine, especially in the care of patients with solid-organ malignancies. …”
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Les broyeurs en pierre en forme de doigt dans le sud-est de la Gaule romaine by Yves Manniez, Vincent Lauras

“…In the first part of our study, and following a review of the history of research carried out by our predecessors on this type of object, we examined and discussed the geographical origin of finger-shaped pestles and their evolution towards stone models. The latter were very popular in the Aegean world and subsequently spread throughout the Roman Empire, until at least the 3rd c. …”
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Antiganglioside Antibodies and Inflammatory Response in Cutaneous Melanoma by Corina Daniela Ene, Mircea Tampa, Ilinca Nicolae, Cristina Iulia Mitran, Madalina Irina Mitran, Clara Matei, Ana Caruntu, Constantin Caruntu, Simona Roxana Georgescu

“…Endogenously produced antiganglioside antibodies could affect the evolution of cutaneous melanoma. Epidemiological and experimental evidence suggest “chronic inflammation” to be one of the hallmarks in skin cancers. …”
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Diagnosis of Peritonsillar Abscess—A Prospective Study Comparing Clinical with CT Findings in 133 Consecutive Patients by François Voruz, Rebecca Revol, Christophe Combescure, Yan Monnier, Minerva Becker, Nicolas Dulguerov

“…The standard of reference consisted of surgically proven pus within 24 h of CT or a favorable clinical evolution at 48 h without surgical intervention. <b>Results:</b> PTA was present in 117/133 (88%) patients, with no difference between mean age or sex distribution between the groups with and without PTA. …”
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Aqueous foams in microgravity, measuring bubble sizes by Pasquet, Marina, Galvani, Nicolo, Pitois, Olivier, Cohen-Addad, Sylvie, Höhler, Reinhard, Chieco, Anthony T., Dillavou, Sam, Hanlan, Jesse M., Durian, Douglas J., Rio, Emmanuelle, Salonen, Anniina, Langevin, Dominique

“…A new more general expression of the diffuse intensity transmitted with specific optical boundary conditions has been derived and applied to determine the average bubble radius. The temporal evolution of the average bubble radii deduced from DTS and of the same average radii of the bubbles measured at the sample surface is the same (to a factor probably close to one) throughout the coarsening. …”
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Tissue- and Cell Type-Specific Expression of the Long Noncoding RNA Klhl14-AS in Mouse by Sara Carmela Credendino, Nicole Lewin, Miriane de Oliveira, Swaraj Basu, Barbara D’Andrea, Elena Amendola, Luigi Di Guida, Antonio Nardone, Remo Sanges, Mario De Felice, Gabriella De Vita

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Advancing precision medicine: the transformative role of artificial intelligence in immunogenomics, radiomics, and pathomics for biomarker discovery and immunotherapy optimization by Luchen Chang, Jiamei Liu, Jialin Zhu, Shuyue Guo, Yao Wang, Zhiwei Zhou, Xi Wei

“…These improvements are expected to lead to more accurate, personalized treatment strategies and ultimately better patient outcomes, marking a significant step forward in the evolution of precision medicine.…”
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A complete structural analysis of the FⅠ17 strike-slip fault and its hydrocarbon enrichment factors, Tarim basin, NW China by Shi Chen, Shi Chen, Xinxin Liang, Xinxin Liang, Xingguo Song, Xingguo Song, Yintao Zhang, Zhou Xie, Yuan Neng, Yuan Neng, Pengfei Kang, Jianxun Zhou, Jianxun Zhou

“…Analyzing the FⅠ17 fault offers crucial insights into the role of basement structures on the evolution and formation of intracratonic strike-slip fault systems. …”
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Advances and Challenges in Antiviral Development for Respiratory Viruses by Luis Adrián De Jesús-González, Moisés León-Juárez, Flor Itzel Lira-Hernández, Bruno Rivas-Santiago, Manuel Adrián Velázquez-Cervantes, Iridiana Monserrat Méndez-Delgado, Daniela Itzel Macías-Guerrero, Jonathan Hernández-Castillo, Ximena Hernández-Rodríguez, Daniela Nahomi Calderón-Sandate, Willy Salvador Mata-Martínez, José Manuel Reyes-Ruíz, Juan Fidel Osuna-Ramos, Ana Cristina García-Herrera

“…While current antivirals offer valuable options, they face challenges such as viral evolution and the need for accessible treatments for vulnerable populations. …”
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First genome-scale insights into the virulence of the snow mold causal fungus Microdochium nivale by Ivan Tsers, Ekaterina Marenina, Azat Meshcherov, Olga Petrova, Olga Gogoleva, Alexander Tkachenko, Natalia Gogoleva, Yuri Gogolev, Evgenii Potapenko, Olga Muraeva, Mira Ponomareva, Viktor Korzun, Vladimir Gorshkov

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Influence of magma intrusion and contact distance onthermal effects of low-temperature oxidation processes in coal by Zhijin YU, Ce JIN, Xu TANG, Zhipeng ZHANG, Hu WEN

“…By testing the industrial composition and analyzing the differences in the surface morphology of the samples, it was concluded that magma intrusion metamorphosed the raw coal and increased the number of pores and fissures on the surface, mainly through contact thermal evolution. The metamorphic coals were categorized into strongly eroded coals, weakly eroded coals, and high rank coals of the homogeneous group. …”
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Genome-wide identification of the adaptor protein complexes and its expression patterns analysis in foxtail millet (Setaria italica L.) by Dan Wang, Min Su, Jian-Hong Hao, Zi-Dong Li, Shuqi Dong, Xiangyang Yuan, Xiaorui Li, Lulu Gao, Xiaoqian Chu, Guanghui Yang, Jia-Gang Wang, Huiling Du

“…Gene structure and motif composition were investigated to understand the function and evolution of these SiAP complex genes. Furthermore, these promoter region of the SiAP complex genes contains 49 cis-elements that are associated with responses to light, hormones, abiotic stress, growth and development. …”
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Identity Construction and Transformation of Zen Tourists by Xu Haichao, Liang Zengxian

“…This study enriches the research on the identity and role evolution of tourists in religious contexts, emphasizing the need for further exploration of how tourists interact with their environment to form experiences, thereby providing more specific insights and understanding of religious tourism in postmodern society. …”
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Macroecological predictors to determine future refuges of Luciobarbus species in the Tigris–Euphrates basin: Rethinking conservation strategies and management by Hadi Khoshnamvand, Seyed Mohsen Mousavi, Asef Darvishi, Kourosh Ahmadi, Amir Naghibi, Karel Janko, Asghar Abdoli, Faraham Ahmadzadeh

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Equalizer Design: HBOA-DE-trained radial basis function neural networks by Santosh Kumar Das, Satya Ranjan Pattanaik, Pradyumna Kumar Mohapatra, Saroja Kumar Rout, Abdulaziz S. Almazyad, Muhammed Basheer Jasser, Guojiang Xiong, Ali Wagdy Mohamed

“…As an optimization algorithm, a nature-inspired hybrid algorithm is applied, namely BOA/DE, which is a combination of the Butterfly optimization algorithm (BOA) and differential evolution (DE). Based on a suitable network topology and transfer function, the presented work proposes an algorithm for training radial basis function neural networks (RBFNNs) that is applied to the problem of channel equalization. …”
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