Antibody-epitope conjugates deliver immunogenic T-cell epitopes more efficiently when close to cell surfaces by W. van der Wulp, W. Luu, M. E. Ressing, J. Schuurman, S. I. van Kasteren, L. Guelen, R. C. Hoeben, B. Bleijlevens, M. H. M. Heemskerk

Subjects: “…antibody-epitope conjugates (AECs)…”
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Fundamentals and Methods for T- and B-Cell Epitope Prediction by Jose L. Sanchez-Trincado, Marta Gomez-Perosanz, Pedro A. Reche

“…Epitope identification is costly and time-consuming as it requires experimental screening of large arrays of potential epitope candidates. …”
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Automatic Generation of Validated Specific Epitope Sets by Sebastian Carrasco Pro, John Sidney, Sinu Paul, Cecilia Lindestam Arlehamn, Daniela Weiskopf, Bjoern Peters, Alessandro Sette

“…In this context, it is desirable to elucidate a method to select validated reference sets of epitopes to allow detection of T and B cells. However, the ever-growing information contained in the Immune Epitope Database (IEDB) and the differences in quality and subjects studied between epitope assays make this task complicated. …”
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In silico design of an epitope-based vaccine ensemble for fasliolopsiasis by Ruchishree Konhar, Ruchishree Konhar, Kanhu Charan Das, Kanhu Charan Das, Aiboklang Nongrum, Rohan Raj Samal, Shailesh Kumar Sarangi, Devendra Kumar Biswal, Devendra Kumar Biswal

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Structural engineering of stabilized, expanded epitope nanoparticle vaccines for HPV by Michaela Helble, Michaela Helble, Xizhou Zhu, Pratik S. Bhojnagarwala, Kevin Liaw, Yangcheng Gao, Amber Kim, Kelly Bayruns, Madison E. McCanna, Joyce Park, Kylie M. Konrath, Kylie M. Konrath, Sam Garfinkle, Sam Garfinkle, Taylor Brysgel, David B. Weiner, David B. Weiner, Daniel W. Kulp, Daniel W. Kulp

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The Humoral Theory of Transplantation: Epitope Analysis and the Pathogenicity of HLA Antibodies by Edward J. Filippone, John L. Farber

“…Antibodies do not recognize whole HLA molecules but rather polymorphic residues on the surface, called epitopes, which may be shared by multiple serologic HLA antigens. …”
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Advancing risk stratification in kidney transplantation: integrating HLA-derived T-cell epitope and B-cell epitope matching algorithms for enhanced predictive accuracy of HLA compatibility by Matthias Niemann, Matthias Niemann, Benedict M. Matern, Benedict M. Matern, Gaurav Gupta, Bekir Tanriover, Fabian Halleck, Klemens Budde, Eric Spierings, Eric Spierings

“…IntroductionThe immune-mediated rejection of transplanted organs is a complex interplay between T cells and B cells, where the recognition of HLA-derived epitopes plays a crucial role. Several algorithms of molecular compatibility have been suggested, each focusing on a specific aspect of epitope immunogenicity.MethodsConsidering reported death-censored graft survival in the SRTR dataset, we evaluated four models of molecular compatibility: antibody-verified Eplets, Snow, PIRCHE-II and amino acid matching. …”
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Epitope-imprinted biomaterials with tailor-made molecular targeting for biomedical applications by Youlu Diao, Jia Gao, Yue Ma, Guoqing Pan

Subjects: “…Epitope imprinting…”
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T and B cell epitope analysis for the immunogenicity evaluation and mitigation of antibody-based therapeutics by Ruoxuan Sun, Mark G. Qian, Xiaobin Zhang

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Immunoinformatic strategy for developing multi-epitope subunit vaccine against Helicobacter pylori. by Md Nahian, Md Rasel Khan, Fabiha Rahman, Hossain Mohammed Reza, Imren Bayil, Tanjum Ahmed Nodee, Tabassum Basher, Mostafizur Rahaman Sany, Rabeya Najnin Munmun, S M Ariful Habib, Lincon Mazumder, Mrityunjoy Acharjee

“…In this study, we employed an immunoinformatic strategy to design a set of candidate multi-epitope subunit vaccines by combining the most potent B and T cell epitopes from three targeted antigenic proteins (BabA, CagA, and VacA). …”
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Computational Approaches to Facilitate Epitope-Based HLA Matching in Solid Organ Transplantation by Kirsten Geneugelijk, Jeroen Wissing, Dirk Koppenaal, Matthias Niemann, Eric Spierings

“…Epitope-based HLA matching has been emerged over the last few years as an improved method for HLA matching in solid organ transplantation. …”
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Discovery of conserved peptide-MHC epitopes for directly alloreactive CD8+ T cells by Alexandra E. Hill, Eric T. Son, Moumita Paul-Heng, Chuanmin Wang, Shivanjali Ratnaseelan, Martina Denkova, Pouya Faridi, Asolina Braun, Anthony W. Purcell, Nicole A. Mifsud, Alexandra F. Sharland

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Development of a broad-spectrum epitope-based vaccine against Streptococcus pneumoniae. by Md Nahian, Muhammad Shahab, Md Rasel Khan, Shopnil Akash, Tanjina Akhtar Banu, Murshed Hasan Sarkar, Barna Goswami, Sanjana Fatema Chowdhury, Mohammad Ariful Islam, Ahmed Abu Rus'd, Shamima Begum, Ahashan Habib, Aftab Ali Shaikh, Jonas Ivan Nobre Oliveira, Shahina Akter

“…Two potential vaccine candidates, CbpA and PspA, were identified, and their B-cell, CTL, and HTL epitopes were predicted and connected with suitable linkers, adjivant and PADRE sequence. …”
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Development of a broad-spectrum epitope-based vaccine against Streptococcus pneumoniae by Md. Nahian, Muhammad Shahab, Md. Rasel Khan, Shopnil Akash, Tanjina Akhtar Banu, Murshed Hasan Sarkar, Barna Goswami, Sanjana Fatema Chowdhury, Mohammad Ariful Islam, Ahmed Abu Rus’d, Shamima Begum, Ahashan Habib, Aftab Ali Shaikh, Jonas Ivan Nobre Oliveira, Shahina Akter

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Computer-Aided Design of an Epitope-Based Vaccine against Epstein-Barr Virus by Julio Alonso-Padilla, Esther M. Lafuente, Pedro A. Reche

“…Herein, we applied a computer-aided strategy to design a prophylactic epitope vaccine ensemble from experimentally defined T and B cell epitopes. …”
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An Immunoinformatics Study to Predict Epitopes in the Envelope Protein of SARS-CoV-2 by Renu Jakhar, S. K. Gakhar

“…The bioinformatics analysis was carried out by using the Immune Epitope Database (IEDB) to predict B- and T-cell epitopes. …”
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Sculpting multi-epitope vaccine against Monkeypox viral strains using immunoinformatics by Zaira Rehman, Ammad Fahim, Maryam Irtash

“…All the epitopes have 97.5% worldwide population coverage. …”
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Characterization of two neutralizing monoclonal antibodies with conformational epitopes against porcine deltacoronavirus by Wan Lu, Hongtao Cao, Yongle Yang, Yangyang Sun, Dong Yang, Priscilla F. Gerber, Xiangdong Li, Yaowei Huang, Bin Wang

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Variations in the composition and frequency of celiac disease epitopes among synthetic wheat lines by Rahman Ebrahimzadegan, Ghader Mirzaghaderi

“…By searching the previously identified 121 epitopes and those with one mismatch in our amplicons, we found 54 different α-gliadins epitopes across our genotypes, four of which were new variants. …”
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Databases and Associated Bioinformatic Tools in Studies of Food Allergens, Epitopes and Haptens – a Review by Bucholska Justyna, Minkiewicz Piotr, Darewicz Małgorzata, Iwaniak Anna

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