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Epitope mapping of recombinant Salmonella enterica serotype Heidelberg flagellar hook-associated protein by in silico and in vivo approaches
Published 2025-02-01Subjects: Get full text
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42
Designing a broad-spectrum multi-epitope subunit vaccine against leptospirosis using immunoinformatics and structural approaches
Published 2025-01-01Subjects: Get full text
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Naturally Occurring Hepatitis B Virus B-Cell and T-Cell Epitope Mutants in Hepatitis B Vaccinated Children
Published 2013-01-01“…The aim of this study was to investigate the role of B-cell and T-cell epitope variations of HBsAg and polymerase in HBV infection in vaccinated children. …”
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Design of Epitope-Based Peptide Vaccine against Pseudomonas aeruginosa Fructose Bisphosphate Aldolase Protein Using Immunoinformatics
Published 2020-01-01“…Six MHC I epitopes were found to be promising, while four MHC II epitopes were found promising from the result set. …”
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Comprehensive Analysis of the Immune Response to SARS-CoV-2 Epitopes: Unveiling Potential Targets for Vaccine Development
Published 2025-01-01Subjects: Get full text
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46
Identification of Two Novel HLA-A∗0201-Restricted CTL Epitopes Derived from MAGE-A4
Published 2010-01-01“…MAGE-A antigens and their epitope peptides have been used in tumor immunotherapy trials. …”
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The amino acids differences in epitopes may promote the different allergenicity of ovomucoid derived from hen eggs and quail eggs
Published 2023-05-01Subjects: Get full text
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Computational design, expression, and characterization of a Plasmodium falciparum multi-epitope, multi-stage vaccine candidate (PfCTMAG)
Published 2025-01-01Subjects: Get full text
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49
Next-generation sequencing and immuno-informatics for designing a multi-epitope vaccine against HSV-1-induced uveitis
Published 2025-01-01Subjects: “…epitopes…”
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The Occurrence of Sequences Identical with Epitopes from the Allergen Pen a 1.0102 Among Food and Non-Food Proteins
Published 2015-03-01Subjects: Get full text
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51
Immunoinformatics Approach for Epitope-Based Peptide Vaccine Design and Active Site Prediction against Polyprotein of Emerging Oropouche Virus
Published 2018-01-01“…Eighteen highly antigenic and immunogenic CD8+ T-cell epitopes were identified, including three 100% conserved epitopes (TSSWGCEEY, CSMCGLIHY, and LAIDTGCLY) as the potential vaccine candidates. …”
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Immunization of cattle with a Rhipicephalus microplus chitinase peptide containing predicted B-cell epitopes reduces tick biological fitness
Published 2024-08-01Subjects: “…B-cell epitope…”
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Interferon-γ production in response to the cytotoxic T lymphocyte epitope within an antigen incorporated in simian virus 40 virus-like particles
Published 2025-01-01“…In this study, administration of chicken ovalbumin (OVA) incorporated within SV40 VLPs induced interferon (IFN)-γ production in response to the OVA CTL epitope. IFN-γ production in response to the OVA CTL epitope was not inhibited in B cell-depleted mice, but it was inhibited in cluster of differentiation (CD)4+ T cell-depleted mice. …”
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Corrigendum: A self-assembled nanoparticle vaccine elicits effective neutralizing antibody response against EBV infection
Published 2025-02-01Subjects: Get full text
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56
Optimizing lipopeptide bioactivity: The impact of non-ionic surfactant dressing
Published 2024-12-01Subjects: Get full text
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A self-assembled nanoparticle vaccine elicits effective neutralizing antibody response against EBV infection
Published 2025-01-01Subjects: Get full text
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Characterisation of EfbA from the Endodontic Pathogen Enterococcus faecalis and Prediction of Immunodominant EfbA Epitope Peptides: An In-vitro and In-silico Study
Published 2025-01-01“…Docking of the epitopes with reference to Human Leukocyte Antigens (HLA) alleles was assessed using the ClusPro server, and the results were evaluated for the T-cell dominant epitopes. …”
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Predicted indirectly recognizable HLA epitopes scores and clinical outcomes after haploidentical stem cell transplantation in pediatric patients with relapsed neuroblastoma
Published 2025-01-01“…IntroductionThe Predicted Indirectly ReCognizable HLA Epitopes (PIRCHE) model is a recently developed algorithm that predicts indirect T-cell recognition by calculating the number of such epitopes in donor-recipient pairs.MethodsIn this study, the clinical significance of PIRCHE was evaluated in pediatric patients with relapsed/progressed neuroblastoma undergoing haploidentical stem cell transplantation (haplo-SCT).ResultsA higher PIRCHE-I score was associated with faster platelet recovery (P = 0.007) and lower incidence of hemorrhagic cystitis (13% vs. 41%, P = 0.028) and invasive fungal infections (0% vs. 18%, P = 0.045). …”
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Sp17 Protein Expression and Major Histocompatibility Class I and II Epitope Presentation in Diffuse Large B Cell Lymphoma Patients
Published 2017-01-01“…The aim of the present study was to investigate Sp17 epitope presentation via the presence of a cytotoxic T cell (CTL) and a CD4 T-helper (Th) response in DLBCL patients. …”
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