Showing 81 - 100 results of 755 for search '"epigenetics"', query time: 0.05s Refine Results
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    Role of Epigenetic Histone Modifications in Diabetic Kidney Disease Involving Renal Fibrosis by Jing Sun, Yangwei Wang, Wenpeng Cui, Yan Lou, Guangdong Sun, Dongmei Zhang, Lining Miao

    Published 2017-01-01
    “…There is evidence to suggest that in diabetes and hyperglycemia, epigenetic histone modifications have a significant effect in modulating renal fibrotic and ECM gene expression induced by TGF-β1, as well as its downstream profibrotic genes. …”
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  3. 83

    Computational Modelling Approaches on Epigenetic Factors in Neurodegenerative and Autoimmune Diseases and Their Mechanistic Analysis by Afroza Khanam Irin, Alpha Tom Kodamullil, Michaela Gündel, Martin Hofmann-Apitius

    Published 2015-01-01
    “…This review examines the major milestones in epigenetics research in the context of diseases and various computational approaches developed in the last decades to unravel new epigenetic modifications. …”
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    Non-pharmaceutical interventions and epigenetic aging in adults: Protocol for a scoping review. by Alina Liebich, Shenglin Zheng, Theresa Schachner, Jacqueline Mair, Mia Jovanova, Falk Müller-Riemenschneider, Tobias Kowatsch

    Published 2024-01-01
    “…Several non-pharmaceutical interventions can lower the risk of NCDs, including common mental disorders (CMDs), and may slow down biological aging, as evidenced by outcome markers such as epigenetic clocks. However, a comprehensive overview of whether and which non-pharmaceutical interventions may impact human epigenetic aging is missing. …”
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    Bidirectional relationship between epigenetic age and stroke, dementia, and late-life depression by Cyprien A. Rivier, Natalia Szejko, Daniela Renedo, Santiago Clocchiatti-Tuozzo, Shufan Huo, Adam de Havenon, Hongyu Zhao, Thomas M. Gill, Kevin N. Sheth, Guido J. Falcone

    Published 2025-02-01
    “…Abstract Chronological age is an imperfect estimate of molecular aging. Epigenetic age, derived from DNA methylation data, provides a more nuanced representation of aging-related biological processes. …”
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  8. 88

    Epigenetic Application of ATAC-Seq Based on Tn5 Transposase Purification Technology by Wangchun Li, U Tim Wu, Yu Cheng, Yanhao Huang, Lipeng Mao, Menghan Sun, Congling Qiu, Lin Zhou, Lijuan Gao

    Published 2022-01-01
    “…These methods can provide a reference for the study of epigenetic regulation of gene expression.…”
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  9. 89

    Epigenetic Dynamics: Role of Epimarks and Underlying Machinery in Plants Exposed to Abiotic Stress by Manoj Kumar Dhar, Parivartan Vishal, Rahul Sharma, Sanjana Kaul

    Published 2014-01-01
    “…We present a lucid review of epigenetic machinery and epigenetic alterations involving DNA methylation, histone tail modifications, chromatin remodeling, and RNA directed epigenetic changes.…”
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    The Mechanisms Underlying Chronic Inflammation in Rheumatoid Arthritis from the Perspective of the Epigenetic Landscape by Yasuto Araki, Toshihide Mimura

    Published 2016-01-01
    “…Epigenetic changes possibly provide RASFs with an activated phenotype. …”
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  13. 93

    Epigenetic and Neurological Impairments Associated with Early Life Exposure to Persistent Organic Pollutants by Nathalie Grova, Henri Schroeder, Jean-Luc Olivier, Jonathan D. Turner

    Published 2019-01-01
    “…The roles of those environmental factors which may affect epigenetic DNA methylation and therefore influence normal neurodevelopment are then evaluated.…”
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  14. 94

    Epigenetic Methylation of Parathyroid CaR and VDR Promoters in Experimental Secondary Hyperparathyroidism by Jacob Hofman-Bang, Eva Gravesen, Klaus Olgaard, Ewa Lewin

    Published 2012-01-01
    “…Methylation of promoter regions is often detected during epigenetic downregulation of gene expression. Therefore, using an experimental rat model, we examined changes in methylation levels of parathyroid CaR and VDR promoters in vivo and in vitro. …”
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  15. 95

    Cardiovascular Risk in Systemic Autoimmune Diseases: Epigenetic Mechanisms of Immune Regulatory Functions by Chary López-Pedrera, Carlos Pérez-Sánchez, Manuel Ramos-Casals, Monica Santos-Gonzalez, Antonio Rodriguez-Ariza, Ma José Cuadrado

    Published 2012-01-01
    “…Epigenetic regulatory mechanisms comprise DNA methylation, histone modifications, and microRNA activity, all of which act upon gene and protein expression levels. …”
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    Small molecules and heat treatments reverse vernalization via epigenetic modification in Arabidopsis by Nana Otsuka, Ryoya Yamaguchi, Hikaru Sawa, Naoya Kadofusa, Nanako Kato, Yasuyuki Nomura, Nobutoshi Yamaguchi, Atsushi J. Nagano, Ayato Sato, Makoto Shirakawa, Toshiro Ito

    Published 2025-01-01
    “…RNA-seq and ChIP-seq analyses revealed both shared and specific transcriptomic and epigenetic effects between DVR06- and heat-induced devernalization. …”
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    Placental, Matrilineal, and Epigenetic Mechanisms Promoting Environmentally Adaptive Development of the Mammalian Brain by Kevin D. Broad, Eridan Rocha-Ferreira, Mariya Hristova

    Published 2016-01-01
    “…Placentation also hands ultimate control of genomic imprinting and intergenerational epigenetic information transfer to the matriline as epigenetic markers undergo erasure and reprogramming in the developing oocyte. …”
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