Showing 61 - 80 results of 755 for search '"epigenetics"', query time: 0.05s Refine Results
  1. 61

    The Possible Role of Epigenetics in Gestational Diabetes: Cause, Consequence, or Both by J. L. Fernández-Morera, S. Rodríguez-Rodero, E. Menéndez-Torre, M. F. Fraga

    Published 2010-01-01
    “…Several risk factors of GDM depend on environmental factors that are thought to regulate the genome through epigenetic mechanisms. Thus, epigenetic regulation could be involved in the development of GDM. …”
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    What Is in the Field for Genetics and Epigenetics of Diabetic Neuropathy: The Role of MicroRNAs by V. Spallone, C. Ciccacci, A. Latini, P. Borgiani

    Published 2021-01-01
    “…It considered in more depth the pathogenetic implications for diabetic neuropathy of the polymorphism of MIR499A and the related changes in the downstream action of miR-499a, showing how epigenetic and genetic studies may provide insight into pathogenetic mechanisms like mitochondrial dysfunction. …”
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  5. 65

    Epigenetic Induction of Definitive and Pancreatic Endoderm Cell Fate in Human Fibroblasts by Rangarajan Sambathkumar, Eric Kalo, Rob Van Rossom, Marijke M. Faas, Paul de Vos, Catherine M. Verfaillie

    Published 2016-01-01
    “…Our findings underscore the role epigenetic modification in transdifferentiation of one somatic cell into another. …”
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    Diagnostic efficacy of serological and epigenetic methods of screening diagnostics of colorectal cancer by O. I. Kit, D. V. Burtsev, A. Yu. Maksimov

    Published 2014-12-01
    “…Diagnostic efficacy of CRC screening diagnostics by testing of blood levels of CEA, СА 242 and СА 19-9 was 40,4, 50,8 and 51,7% respectively. Epigenetic tests for DNA methylate of SEPT9 gene in blood as screening procedure was characterized by high diagnostic efficacy — 86,5%. …”
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  9. 69

    Mitochondrial DNA variants and their impact on epigenetic and biological aging in young adulthood by Klara Mareckova, Ana Paula Mendes-Silva, Martin Jáni, Anna Pacinkova, Pavel Piler, Vanessa F. Gonçalves, Yuliya S. Nikolova

    Published 2025-01-01
    “…A subset of these participants (n = 69) also had epigenetic data to estimate epigenetic aging in the early 20s using Horvath’s epigenetic clock. …”
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  10. 70

    Epigenetic Mechanisms in Type-2 Diabetes Mellitus: A Narrative Review by Deenadhayalan Ashok, Monisha Prasad, Mohammad Fareed, Anis Ahmad Chaudhary

    Published 2025-01-01
    “…The systems that mediate the interaction between environmental factors and the genes, such as epigenetics, may have a specific bearing on the aetiology of T2DM. …”
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  11. 71

    D-2-hydroxyglutarate impairs DNA repair through epigenetic reprogramming by Fengchao Lang, Karambir Kaur, Haiqing Fu, Javeria Zaheer, Diego Luis Ribeiro, Mirit I. Aladjem, Chunzhang Yang

    Published 2025-02-01
    “…Abstract Cancer-associated mutations in IDH are associated with multiple types of human malignancies, which exhibit distinctive metabolic reprogramming, production of oncometabolite D-2-HG, and shifted epigenetic landscape. IDH mutated malignancies are signatured with “BRCAness”, highlighted with the sensitivity to DNA repair inhibitors and genotoxic agents, although the underlying molecular mechanism remains elusive. …”
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  12. 72

    New Insights into the Androgen-Targeted Therapies and Epigenetic Therapies in Prostate Cancer by Abhijit M. Godbole, Vincent C. O. Njar

    Published 2011-01-01
    “…We also summarize recent findings about the antiandrogens and the epigenetic factors that modulate the action of AR.…”
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    Role of Epigenetics in Modulating Phenotypic Plasticity against Abiotic Stresses in Plants by Fayaz Ahmad Dar, Naveed Ul Mushtaq, Seerat Saleem, Reiaz Ul Rehman, Tanvir Ul Hassan Dar, Khalid Rehman Hakeem

    Published 2022-01-01
    “…Plants being sessile are always exposed to various environmental stresses, and to overcome these stresses, modifications at the epigenetic level can prove vital for their long-term survival. …”
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  16. 76

    Epigenetic regulation of bone remodeling and its role in the pathogenesis of primary osteoporosis by B. I. Yalaev, R. I. Khusainova

    Published 2023-07-01
    “…Systematisation of these data is important to investigate the differences in epigenetic marker arrays by race and ethnicity. The review article analyses references to relevant reviews and original articles, classifies information on current advances in the study of epigenetic mechanisms in osteoporosis and reviews the results of studies of epigenetic mechanisms on individual links of bone remodelling.…”
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