Changes in the Intestinal Microbiota in Patients with Chronic Pancreatitis: Systematizing Literature Data by I. V. Maev, A. I. Levchenko, D. N. Andreev

“…The severe CP is associated with impaired synthesis of antimicrobial peptides, bicarbonates, and digestive enzymes by the pancreas, which is a risk factor for dysbiotic changes in the intestinal microbiota, consisting in the development of small intestinal bacterial overgrowth (SIBO) and gut dysbiosis. …”
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Probing the role of Coniferin and Tetrahydrocurcumin from Traditional Chinese medicine against PSAT1 in early-stage ovarian cancer: An in silico study. by Jia Zhang, Shalesh Gangwar, Nagmi Bano, Shaban Ahmad, Mohammed S Alqahtani, Khalid Raza

“…In this work, we used computational approaches to find putative Traditional Chinese Medicine (TCM) inhibitors that target Phosphoserine Aminotransferase 1 (PSAT1), a crucial enzyme linked to the development of early-stage ovarian cancer. …”
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Peptidoglycan recognition protein PGRP-5 is involved in immune defence and neuro-behavioral disorders in zebrafish embryos. by Xi Li, Guanghua Xiong, Manni Luo, Siwan Mao, Ruiying Zhang, Ziwei Meng, Juan Li, Xinjun Liao

“…On the other hand, the locomotor behavior abilities and the antioxidant enzyme activities such as CAT and SOD were obviously decreased under the DrPGRP-5 KD conditions. …”
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Glucoraphanin conversion into sulforaphane and related compounds by gut microbiota by Tetiana R. Dmytriv, Tetiana R. Dmytriv, Oleh Lushchak, Oleh Lushchak, Volodymyr I. Lushchak, Volodymyr I. Lushchak

“…Sulforaphane is formed by the hydrolysis of glucoraphanin by a plant enzyme called myrosinase, which is inactivated in the stomach of mammals. …”
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Thymol maintains peppers quality by regulating antioxidant capacity, cell wall metabolism and membrane lipid metabolism by Xue Li, Xiaogang Wang, Jianye Chen, Donglan Luo, Sen Cao, Liangjie Ba

“…Additionally, thymol application inhibited the hydrolysis of pepper cell wall components and decreased the activities of enzymes related to cell wall and membrane lipid metabolism. …”
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AI-driven prediction of drug activity against Toxoplasma gondii: Data augmentation and deep neural networks for limited datasets by Natalia V. Karimova, Ravithree D. Senanayake

“…Toxoplasmosis, caused by Toxoplasma gondii (T. gondii), is a serious global health concern, particularly in immunocompromised individuals. Inhibiting the enzyme TgDHFR is a promising strategy for developing treatments. …”
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Markers of chronic hepatitis B at patients with HIV-infection and treatment approaches by S. I. Maksimov, S. P. Tsarenko, A. V. Kravchenko, N. Yu. Gankina, N. D. Yushchuk

“…All blood samples were investigated for the presence of НBV, HDV, HCV, HAV-virus markers in serum by enzyme-linked immunoassay and for the presence of RNA HIV, RNA HCV and DNA HBV by polymerase chain reaction.Results. …”
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Correlation of Serum and Gingival Crevicular Fluid Levels of Caspase-3 and Milk Fat Globule–Epidermal Growth Factor 8 on Gingival Health by Manonmani Pavithra Ravindran, A Geetha, Sathish Rajendran, Jaideep Mahendra, M Jyothi, Ambalavanan Namasivayam

“…After recording the periodontal parameters (plaque index (PI), modified gingival index (MGI), probing depth (PD) and clinical attachment level (CAL)), the serum and GCF samples were collected and the levels of caspase-3 and MFG-E8 were estimated using enzyme-linked immunoassay (ELISA). Results: The mean values of PI, MGI, PD and CALs were significantly higher in group III when compared to group II and group I. …”
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Antihypertensive effect of sinapine extracted from rapeseed meal in 2K1C hypertensive rats by Gaoyuan Yang, Lin Zhu, Yu Wang, Yang Yu, Xiaoguang Liu, Jingbo Xia, Yunjie Yang, Huiguo Wang, Baomin Feng

“…The renin angiotensin aldosterone system (RAAS), including the levels of renin, angiotensin I (Ang I), angiotensin II (Ang II), aldosterone (ALD), angiotensin-converting enzyme (ACE) and other molecules related to blood pressure, such as NO, prostacyclin (PGI2), endothelin-1 (ET1), and thromboxane A2 (TXA2), were measured in rat blood. …”
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Carboxypeptidase B1 in dialyzed chronic kidney disease patients by Matej Stančík, Marián Grendár, Marián Mokáň

“…Abstract Carboxypeptidase B1 has long been known to be a pancreas-specific tissue enzyme. In this paper we focus on Carboxypeptidase B1 concentration measurement in dialyzed chronic kidney kidney disease patients and on the effect dialysis adequacy and regimen exert on its concentration. …”
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How endocrine disruptors affect fish reproduction on multiple levels: A review by Socha Magdalena, Chyb Jarosław, Suder Aleksandra, Bojarski Bartosz

“…These substances, including bisphenols, heavy metals, pesticides, phthalates, and polychlorinated biphenyls (PCBs), act as hormone mimics, receptor blockers, or enzyme inhibitors that affect hormonal regulation in the hypothalamic-pituitary-gonadal (HPG) axis. …”
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Mediators of intercellular interactions and histological signs of chronic viral liver disease by P. V. Koroy, A. V. Yagoda, G. I. Gilyazova, I. S. Mukhoramova

“…Scores of ICAM-1, VCAM-1, Е-selectin, L-selectin and the Р-selectin were determined by enzyme-linked immunoassay method and were compared to values of Knodell histological activity index and Desmet fibrosis score as well as to E.M. …”
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Effect of Ozone Combined with 1-MCP on the Color and Quality of Nectarines during Postharvest Storage by Chen LIU, Yibin ZHANG, Xiaoyu JIA, Zhiyong ZHAO

“…Compared with 1-MCP group alone, 1-MCP group combined with ozone treatment had higher anthocyanin content, centaurin-3-O-glucoside content, centaurin-3-O-rutin content and enzyme activity related to anthocyanin metabolism at the later stage of storage. …”
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Liver and spleen elastography in diagnosis of extrahepatic portal vein obstruction: pilot study by M. Yu. Nadinskaya, Ye. O. Liusina, Ch. S. Pavlov

“…Statistically significant difference in serum aminotransferases levels in non-cirrhotic PVT vs Child-Pugh class A HCV-LC was observed: enzyme levels were 1,5-2 fold higher in LC (р…”
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Oxidative Stress and Its Association with COVID-19: A Narrative Review by Hardi Rafat Baqi, Halgord Ali M. Farag, Abdel Hamid H. El Bilbeisi, Rafee Habib Askandar, Amany M. El Afifi

“…Especially the virus’s route to cell entry via angiotensin-converting enzyme 2 (ACE2) receptor is well known that leads to pathogenesis in angiotensin II (AT II) which are critical in NADH/NADPH oxidase inducing ROS generation. …”
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In vitro efficacy of plant growth-promoting rhizobacteria isolated from ginger (Zingiber officinale) rhizosphere for biological control of plant pathogens by Ruth Meike Jayanti, Sabrina Ayu Kristianingrum, Andree Wijaya Setiawan

“…Among them, isolate 235A2 demonstrated the highest potential as a biological control agent, with capabilities including phosphate solubilization, nitrogen fixation, protease enzyme production, and significant inhibition rates of F. oxysporum (13.79%), Colletotrichum sp. (55.56%), and Alternaria sp. (35.61%) in vitro. …”
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Unraveling relationship between the genetic polymorphism CYP2A13 and nicotine metabolism of male smokers in Medan, Indonesia by Noni Novisari Soeroso, Rozaimah Zain-Hamid, Syamsul Bihar, Chaliza Soliha, Fannie Rizki Ananda, Aida

“…Abstract Background Nicotine metabolism significantly influences the levels of harmful nicotine metabolites in smokers. CYP2A13, a key enzyme in nicotine and xenobiotic metabolism, is implicated in tobacco smoke-related lung cancer. …”
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Increased miRNA-375 causes oxidative damage but promotes apoptosis resistance and cell migration in the clam Ruditapes philippinarum by Ming Cong, Zhaoshun Li, Wenwen Tian, Yixian Yu, Yu Che, Jiasen Lv

“…Then, a combined approach of qRT-PCR, enzyme assay, and ultrastructure observation was applied to investigate its regulatory effects on the related genes, cellular parameters, and histological structures, respectively. …”
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Impact of developmental state, p53 status, and interferon signaling on glioblastoma cell response to radiation and temozolomide treatment. by Artem Berezovsky, Oluwademilade Nuga, Indrani Datta, Kimberly Bergman, Thais Sabedot, Katherine Gurdziel, Susan Irtenkauf, Laura Hasselbach, Yuling Meng, Claudius Mueller, Emanuel F Petricoin, Stephen Brown, Neeraja Purandare, Sidhesh Aras, Tom Mikkelsen, Laila Poisson, Houtan Noushmehr, Douglas Ruden, Ana C deCarvalho

“…We observed that activation of NF-κB was positively correlated with the levels of O-6-methylguanine-DNA methyltransferase (MGMT) protein, a direct DNA repair enzyme leading to TMZ resistance, regardless of MGMT promoter methylation status, further supporting the clinical potential for inhibition of NF-kB signaling in GBM treatment. …”
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Combating antibiotic resistance: mechanisms, challenges, and innovative approaches in antibacterial drug development by Aiswarya M. Rajesh, Shraddha Subhash Pawar, Kruthi Doriya, Rambabu Dandela

“…Bacteria have evolved complex resistance strategies, such as enzyme production to neutralize drugs, modifying drug targets, and using efflux pumps to remove antibiotics, significantly reducing drug efficacy. …”
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