Pharmacological inhibition of carbonic anhydrases with a positively charged pyridinium sulfonamide phenocopies the neuroprotective effects of Car9 genetic ablation in a murine sett... by Sara Amiranda, Mariangela Succoio, Serenella Anzilotti, Ornella Cuomo, Tiziana Petrozziello, Valentina Tedeschi, Arianna Finizio, Giorgia Mele, Seppo Parkkila, Lucio Annunziato, Giuseppina De Simone, Giuseppe Pignataro, Agnese Secondo, Nicola Zambrano

“…A focus on carbonic anhydrase IX showed that ischemic stress altered subcellular distributions of this enzyme in rodent neuronal populations. Given the enzyme's canonical membrane localization, we implemented pharmacological inhibition using a membrane-impermeant sulfonamide inhibitor in neuronal models of brain ischemia. …”
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Effect of seed priming and foliar application of organic liquid manure on germination, growth, yield and quality of late-sown wheat by Okram Ricky Devi, Omvati Verma, Bibek Laishram, S. Anbarasan, Abhijit Debnath, Narinder Panotra, Priyanka Elumle, Sunita T. Pandey, R. Ajaykumar, Samreen

“…From the information presented above, it can be inferred that seed priming with 10% HK along with 100% of the recommended dose of nutrients, followed by foliar applications of 10% HK at various growth stages, increased the growth, productivity and enzyme activity of late sown wheat that priming with 10% HK and its foliar application under 100% RDN increased the growth, productivity, grain quality indices, enzyme activities, and economic profitability of late-sown wheat. …”
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IMPACT OF FISH WASTE PROTEIN ENZYMETIC HYDROLYSATE ON GROWTH OF SOME OF Lactobacillus sp. AND Bifidobacterium sp. by A. S. Mohammed

“…They were hydrolysed by pepsin enzyme lyophilized powder ≥ 2500 units/mg conc.1.5gm/100gm protein concentrates for (30, 60, 90, and 120) minutes. …”
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Evolution of copro-tests in active detection of colorectal cancer by V. I. Chissov, N. S. Sergeyeva, Ye. V. Zenkina, N. V. Marshrutina

“…Searches of the laboratory methods, that allow to overcome this restriction, resulted in development several qualitative (rapid) and quantitative enzyme-linked immunoassays for detection of hemoglobin in feces (FIT). …”
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Olive oil increase catalase activity and gluthatione peroxidase level in hyperglycemic rats by Ariani Zaltin Okvenda, Eti Yerizel, Raveinal

“…Catalase activities were measured using the spectrophotometry method, and GSH-Px levels were analyzed using an enzyme-linked immunosorbent assay (ELISA).  Results: Administration of olive oil increased catalase activity compared to the untreated group in alloxan-induced rats. …”
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Current Trends in Treatment for Acid-Dependent Diseases: Clinical Efficacy and Safety of Rabeprazole by O. D. Lopina, B. K. Nurgalieva, T. L. Lapina

“…A lower rabeprazole metabolic dependence on cytochrome P-450 enzyme system renders its antisecretory effect predictable and reduces the risk of interactions with other drugs metabolised through this system. …”
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Viral hepatitis B epidemiology in Sakha republic (Yakutia) by S. I. Semenov, R. G. Savvin, S. G. Nikitina, S. S. Maksimova, V. G. Krivoshapkin, S. S. Sleptsova

“…Data of the Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor) for Sakha republic (report form #1) and results of enzyme-linked immunoassay (EIA) for viral hepatitis markers (HBsAg, a-HBcor IgG, a-HDV, a-HCV) in population of 17 areas of republic were utilized.Results. …”
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The Impact of COVID-19 on Gametes and Endometrium: A Narrative Review by Esra Karatas, Ali Can Gunes, Bilal Esat Temiz, Sezcan Mumusoglu, Gurkan Bozdag

“…Whereas the available data suggest that SARS-CoV-2 interferes with various types of molecular pathways in the oocyte, spermatozoa, and endometrium, the lack of co-expression in angiotensin-converting enzyme 2 and transmembrane protease serine 2 in those cell lines theoretically avoid concerns by patients and reproductive endocrinologists. …”
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Comparison of Vitamin-D binding protein levels in gingival crevicular fluid of pre- and postmenopausal women with and without chronic periodontitis: A clinico-biochemical study by Kaviya Balasubramaniyam, Sankar Lakshmi Sree, Kavitha Jayavel, V. Krishnan, Rajasekar Sundaram

“…GCF DBP levels were evaluated using an enzyme-linked immunosorbent assay kit. Results: There was a significant correlation between menopausal status and periodontal status in relation to GCF DBP levels (P = 0.000). …”
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Mechanism of modified mRNA structure in COVID-19 vaccines for inducing neutralizing antibodies by Sabighoh Zanjabila, Beti Ernawati Dewi

“…Vaccines like BNT162b2 and mRNA-1273 target the receptor-binding domain (RBD) of the spike (S) protein, prompting B cells to produce neutralizing antibodies that block the RBD from binding to the Angiotensin-Converting Enzyme 2 (ACE2) receptor, preventing infection. These vaccines also stimulate adaptive immune responses by activating CD4+ and CD8+ T cells, with mRNA functioning as an endogenous antigen. …”
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Enzymatic functionalization of bacterial nanocellulose: current approaches and future prospects by Monika Kaczmarek, Aneta Monika Białkowska

“…An alternative to these procedures is the highly specific enzymatic modification of bacterial nanocellulose, which perfectly fits into the assumptions of green technologies, making the process eco-friendly and not limiting any outlooks for further usage of the obtained biocomposites. The employment of enzymes for the targeted alteration of this material’s properties is based on either a direct method, such as controlled hydrolysis and nanofication [i.e., synthesis of different morphological forms of bacterial cellulose (e.g., rod-shaped nanocrystals)] using cellulases, and/or attachment of reactive functional groups into the polymer structure via oxidation (e.g., utilizing a laccase/TEMPO catalytic system or lytic polysaccharide monooxygenases) and esterification catalyzed by lipases; or an indirect procedure involving the application of bacterial nanocellulose as a matrix for enzyme immobilization (e.g., laccase, glucose oxidase, horseradish peroxidase, lysozyme, bromelain, lipase, papain), thus creating a specific catalytic system. …”
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FDA’s approval of resmetirom (Rezdiffra): a breakthrough in MASH management by Muhammad Mazhar Azam, Sameen Mukhtar, Muhammad Haris, Fatima Laique, Suhaina Amir, Mubashir Mohiuddin, Bibek Giri

“…This mechanism effectively reduces fibrosis markers, improves liver enzyme levels, and minimizes liver fat buildup. Clinical trials have shown that resmetirom has a favorable safety profile, with manageable side effects like diarrhea and nausea. …”
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Fifty years after the discovery of the association of HLA B27 with ankylosing spondylitis by Joachim Sieper, Juergen Braun

“…This is much supported by the role of the endoplasmic reticulum aminopeptidase 1 (ERAP 1) in AS, an enzyme that is responsible for the intracellular trimming of peptides, since polymorphisms of this gene are only associated with HLA-B27+ disease. …”
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Investigation into the sero-molecular prevalence of Brucella melitensis in small ruminants in districts Mohmand and Charsadda Khyber Pakhtunkhwa Pakistan. by Sohaib Ul Hassan, Farhan Anwar Khan, Muhammad Shuaib, Muhammad Shahid, Said Sajjad Ali Shah, Shahrood Ahmed Siddiqui, Anthony Pokoo-Aikins, Ayman A Swelum

“…A total of 400 blood samples were collected from sheep and goats (n = 200 from each species) and analyzed by Rose Bengal precipitation test (RBPT), the indirect enzyme-linked immunosorbent assay (i-ELISA) and polymerase chain reaction (PCR). …”
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Recent advances in small molecule LpxC inhibitors against gram-negative bacteria (2014–2024) by Pengpeng Ji, Meng Ma, Xiaoyue Geng, Jian Zhang

“…Uridine diphosphate-3-O-(hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) is a metalloenzyme cofactored with zinc ions, which is a key enzyme in the synthesis of outer membrane lipid A in Gram negative bacteria. …”
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Assessment of Brush Biopsy Findings and Salivary LDH Levels in Oral Mucosal Lesions of Tobacco Users by Sam P. Davidson, Senthil Kumar, Elangovan Somasundaram, Suman Jaishankar

“…Introduction: The oral brush cytology is an alternative method developed to improve the efficacy of conventional cytology in oral potentially malignant disorder (OPMD), and salivary lactate dehydrogenase (LDH) which is a cytoplasmic enzyme has been widely used as a marker for diagnosing various diseases. …”
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Nanozyme-based aptasensors for the detection of tumor biomarkers by Ke Wang, Xiaogang Lin, Xiao Lv, Mingna Xie, Jinyu Wu, Jie Jayne Wu, Yang Luo

“…Nanozymes are nanomaterials that possess enzyme-like properties, demonstrating substantial potential for enhancing the sensing capabilities of biosensors. …”
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Combined Effects of Humic Acid-Modified Magnetic Biochar and AMF on the Properties of Saline-Alkali Soil and Photosynthetic Parameters of Muskmelon by ZHANG Yating, LOU Xueyi, WU Jiarui, LIU Hongyuan, YE Binyu, XIAO Jiamin, LI Jiameng, MIAO Yining, CHEN Xinyan, LIU Yilin, TAN Yuyu, WANG Zhichao, LIU Peng

“…Moreover, by conducting pot experiments, the influence of individual fungi, individual biochar, and combined biochar-fungi (AMF+10%B, AMF+20%B) on the physicochemical properties, and enzyme activities of saline soil and alkaline soil, and the photosynthetic parameters of muskmelon were studied. …”
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New advances in biological preservation technology for aquatic products by Xiaobao Nie, Zhijie Zuo, Ruichang Zhang, Si Luo, Yongzhou Chi, Xiangyang Yuan, Chengwen Song, Yongjiang Wu

“…Moreover, the preservation mechanisms of bio-preservatives, including antioxidant activity, inhibition of spoilage bacteria and enzyme activity, and the formation of protective films are reviewed. …”
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Exogenously applied ABA alleviates dysplasia of maize (Zea mays L.) ear under drought stress by altering photosynthesis and sucrose transport by Zizhu Jiang, Yu Peng Li, Ping Zhuo Gai, Jinsheng Gao, Lijian Xu

“…Exogenous ABA inhibited bald tip and the decline of maize plant biomass, and increased the number and weight of grains per ear at harvest under drought stress by regulating photosynthetic pigment content (Chla, Chlb, Car), gas exchange parameters (Pn, Tr, gs, Ci, Ls), Chla fluorescence parameters (Fv/Fm, ФPSII, ETR, qP, NPQ), chloroplast structure and function, photosynthetic enzyme activity, and the transcription level of genes coding SUTs (ZmSUT1, ZmSUT2, ZmSUT4, ZmSUT6). …”
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