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3721
Metabolic and Hepatic Effects of Energy-Reduced Anti-Inflammatory Diet in Younger Adults with Obesity
Published 2021-01-01“…Metabolic status was determined with glycaemic and lipid status, inflammatory status with hs-CRP, IL-6, and TNF-α, and liver status with liver enzymes, NAFLD-FLS, FLI, and FIB-4 indices. The inflammatory potential of the diet was assessed by the Dietary Inflammatory Index, DII®. …”
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3722
Transcriptomic Analysis of Pathogenicity Genes in Sclerotinia sclerotiorum Affecting Brassica napus
Published 2024-09-01“…., cell wall-degrading enzymes, biosynthesis of secondary metabolites & metabolic pathways) to infect its host plant.…”
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3723
Assessment of Anti-Inflammatory and Antioxidant Activities of a Proprietary Preparation of Quercetin–Rutin Blend (SophorOx™) in Exercised Rats
Published 2024-01-01“…Rats that received SophorOx™ showed no signs of adverse effects, and no significant changes were observed in body weight, feed consumption, liver enzymes, and blood glucose levels. The exercise-treated rats administered with SophorOx™ exhibited a significant reduction in oxidative and inflammatory marker levels, viz., CRP (113.32 ng·mL−1) and oxidative stress markers 8-OHdG (19.32 pg·mL−1), MDA (1.06 nmol·mL−1), 8-iso-PGF2α (1.29 ng·mL−1), IL-1β (0.77 pg·mL−1), and IL-6 (317.14 pg·mL−1) in comparison to those rodents that were exercised without SophorOx™. …”
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3724
High Expression of Ten Eleven Translocation 1 Is Associated with Poor Prognosis in Hepatocellular Carcinoma
Published 2023-01-01“…However, the effect of DNA demethylation enzymes, ten eleven translocation (TET) proteins, has not been comprehensively characterized in liver cancer. …”
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3725
A genome-wide association study identified SNP markers and candidate genes associated with morphometric fruit quality traits in mangoes
Published 2025-02-01“…Gene annotation of the significant markers revealed candidate genes coding for important proteins, enzymes, and transcription factors associated with fruit development traits.…”
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3726
Anti-Inflammatory Activities of Some Plants of Genus Alpinia: Insights from In Vitro, In Vivo, and Human Studies
Published 2025-01-01“…Studies in animal models revealed that the plants contributed as exogenous antioxidants, reduced proinflammatory cytokines, inhibited proinflammatory enzymes, improved gastric acid and gastrointestinal motility, and promoted ulcer healing. …”
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3727
Alterations of Dopamine-Related Transcripts in A11 Diencephalospinal Pathways after Spinal Cord Injury
Published 2021-01-01“…Similar mRNA levels of DA-related enzymes were detected in the A11 neuronal soma between naïve and SCI rats. …”
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3728
Beneficial Effects of Ursodeoxycholic Acid on Metabolic Parameters and Oxidative Stress in Patients with Type 2 Diabetes Mellitus: A Randomized Double-Blind, Placebo-Controlled Cli...
Published 2024-01-01“…After two months of the intervention period, a significant decrease in the activity of liver enzymes was noticed. Furthermore, a significant reduction in prooxidative parameters (TBARS, NO2-, H2O2) and significant elevation in antioxidative parameters such as SOD and GSH were found (p<0.001). …”
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3729
Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 21: Suitability of taxonomic...
Published 2025-01-01“…Of 54 microorganisms notified to EFSA between April and September 2024 (33 as feed additives, 17 as food enzymes or additives, 4 as novel foods), 50 were not evaluated because: 12 were filamentous fungi, 1 was Enterococcus faecium and 8 were Escherichia coli (all excluded from the QPS evaluation), and 29 were TUs that already have a QPS status. …”
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3730
Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature
Published 2020-01-01“…Case. 31-year-old female, one week after delivery, presented to the emergency department with abdominal pain, nausea and vomiting, tenderness in the epigastrium, and raised pancreatic enzymes. Ultrasound (USG) showed bulky pancreas with gallstones. …”
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3731
Risk factors for hepatocellular carcinoma: an umbrella review of systematic review and meta-analysis
Published 2025-12-01“…Smoking, obesity, non-alcoholic fatty liver disease, diabetes, low platelet, elevated liver enzymes and liver fluke infection increase HCC risk, while coffee consumption, a healthy diet, and bariatric surgery lower it. …”
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3732
Hepatitis B virus hijacks MRE11-RAD50-NBS1 complex to form its minichromosome.
Published 2025-01-01“…These findings provide insights into how HBV hijacks host enzymes to establish chronic infection and reveal new therapeutic opportunities.…”
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3733
Impact of predictive selection of LbCas12a CRISPR RNAs upon on‐ and off‐target editing rates in soybean
Published 2024-08-01“…Abstract Clustered regularly interspaced short palindromic repeats (CRISPR) technology has revolutionized creating targeted genetic variation in crops. Although CRISPR enzymes have been reported to have high sequence‐specificity, careful design of the editing reagents can also reduce unintended edits at highly homologous sites. …”
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3734
Research note: Increased lipid accumulation within broiler preadipocytes during differentiation in vitro at atmospheric oxygen tension
Published 2025-01-01“…Abundance of glutathione peroxidase 4 (GPX4) was increased in all the differentiation cultures compared to the controls, regardless of oxygen tension; however, differences in the abundance of other antioxidant enzymes were not observed. Overall, exposure to atmospheric oxygen tension promotes lipid accumulation within chicken preadipocytes, which may need to be considered when developing in vitro models of this process.…”
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3735
Multi-stage structure-based virtual screening approach combining 3D pharmacophore, docking and molecular dynamic simulation towards the identification of potential selective PARP-1...
Published 2025-02-01“…Abstract Presently, humanity is confronted with a range of diseases that have high death rates, especially those linked to cancerous growths. Several enzymes and proteins have been discovered as highly attractive targets for cancer treatment. …”
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3736
Split Application of Potassium Reduces Rice Chalkiness by Regulating Starch Accumulation Process Under High Temperatures
Published 2025-01-01“…Similarly, the gene expression levels of enzymes involved in this process were decreased by 3.52–24.12% at 5 DAA but increased by 8.61–30.00% at 20 DAA by the split application of K fertilizer. …”
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3737
Molecular Epidemiology and Antimicrobial Resistance of Extended-Spectrum β-Lactamase (ESBL)-Producing Klebsiella pneumoniae in Retail Cattle Meat
Published 2024-01-01“…Antimicrobial susceptibilities were assessed using disk diffusion in accordance with the Clinical and Laboratory Standards Institute (CLSI, 2020) guidelines. Genes encoding ESBL enzymes were detected by the double-disk synergy test (DDST) and multiplex PCR. …”
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3738
Hemoprotein dalam Tubuh Manusia
Published 2012-07-01“…Base on Fe ion state in heme group, hemoproteins are divided into: (1) Hemoproteins have ion Fe2+ state that can bind oxygen, such as hemoglobin, myoglobin, neuroglobin, and cytoglobin. (2) Hemoproteins have ion Fe3+ state that act as oxidoreductase enzymes, such as cytochrome P450, cytochromes in oxidative phosphorylation, catalase, tryptophan pyrolase, and NO synthase. …”
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3739
Phenotypic Profiling of Selected Cellulolytic Strains to Develop a Crop Residue-Decomposing Bacterial Consortium
Published 2025-01-01“…However, this solution often focuses mostly on selecting microorganisms based on the appropriate enzymic capabilities and neglects the metabolic versatility required to utilize both structural and non-structural components of residues. …”
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3740
Extended-Spectrum β-Lactamase (ESBL) Genotypes among Multidrug-Resistant Uropathogenic Escherichia coli Clinical Isolates from a Teaching Hospital of Nepal
Published 2020-01-01“…Escherichia coli (n = 154), the predominant pathogen associated with UTI, was further investigated for the existence of ESBL enzymes by using conventional phenotypic as well as molecular approaches. …”
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