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341
Emodin protects against severe acute pancreatitis-associated acute lung injury by activating Nrf2/HO-1/GPX4 signal and inhibiting ferroptosis in vivo and in vitro
Published 2025-02-01“…Pancreatic and lung tissue damage was evaluated using histological examination and molecular experiments. Enzyme-linked immunosorbent assays (ELISA) were used to assess the levels of pro-inflammatory cytokines, Fe2+, and associated oxidative stress indicators in the serum and cell supernatant. …”
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342
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343
Exogenous cystine increases susceptibility of drug-resistant Salmonella to gentamicin by promoting oxidation of glutathione metabolism and imbalance of intracellular redox levels
Published 2025-02-01“…The multifunctional electronic enzyme marker was used to determine intracellular reduced glutathione/oxidized glutathione (GSH/GSSG), ferrous iron on (Fe2+), and reactive oxygen species (ROS) levels. …”
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344
Proteomics unveil candidate biomarkers and pathogenesis of subacute thyroiditis
Published 2025-02-01“…Moreover, the top three high-abundance proteins (nicotinamide N-methyltransferase (NNMT), FTL and thymidine phosphorylase (TYMP)) were further validated in the plasma from a larger SAT cohort using an enzyme-linked immunosorbent assay. After adjusting for sex, Spearman correlation analysis showed that NNMT, FTL and TYMP levels were positively correlated with FT3, FT4, T3, T4, Tg and erythrocyte sedimentation rate and negatively correlated with thyroid-stimulating hormone. …”
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345
Genomic characterization of Achromobacter genogroup 20 and identification of a potential species-specific marker
Published 2025-01-01“…The OXA enzyme, designated OXA-1238 (PP446293), differs from OXA-114a by 85 amino acids, with 69% identity. …”
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346
The ameliorative effects of melatonin against BDE-47-induced hippocampal neuronal ferroptosis and cognitive dysfunction through Nrf2-Chaperone-mediated autophagy of ACSL4 degradati...
Published 2025-01-01“…Acyl-CoA synthetase long-chain family member 4 (ACSL4), a key lipid metabolism enzyme dictating ferroptosis sensitivity, accompanied by higher MDA and lipid reactive oxygen species (ROS), was remarkably increased under BDE-47 stress, while melatonin supplementation could suppress the elevated ACSL4 in vivo and in vitro. …”
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347
Biochemistry : the molecular basis of life /
Published 2017Table of Contents: “…Machine generated contents note: -- Table of Contents -- Chapter 1 Biochemistry: An Introduction -- Chapter 2 Living Cells -- Chapter 3 Water: The Matrix of Life -- Chapter 4 Energy -- Chapter 5 Amino Acids, Peptides, and Proteins -- Chapter 6 Enzymes -- Chapter 7 Carbohydrates -- Chapter 8 Carbohydrate Metabolism -- Chapter 9 Aerobic Metabolism I: The Citric Acid Cycle -- Chapter 10 Aerobic Metabolism II: Electron Transport and Oxidative Phosporylation -- Chapter 11 Lipids and Membranes -- Chapter 12 Lipid Metabolism -- Chapter 13 Photosynthesis -- Chapter 14 Nitrogen Metabolism I: Synthesis -- Chapter 15 Nitrogen Metabolism I: Degradation -- Chapter 16 Integration of Metabolism -- Chapter 17 Nucleic Acids -- Chapter 18 Genetic Information -- Chapter 19 Protein Synthesis.…”
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348
Biochemistry : the molecular basis of life /
Published 2017Table of Contents: “…Machine generated contents note: -- Table of Contents -- Chapter 1 Biochemistry: An Introduction -- Chapter 2 Living Cells -- Chapter 3 Water: The Matrix of Life -- Chapter 4 Energy -- Chapter 5 Amino Acids, Peptides, and Proteins -- Chapter 6 Enzymes -- Chapter 7 Carbohydrates -- Chapter 8 Carbohydrate Metabolism -- Chapter 9 Aerobic Metabolism I: The Citric Acid Cycle -- Chapter 10 Aerobic Metabolism II: Electron Transport and Oxidative Phosporylation -- Chapter 11 Lipids and Membranes -- Chapter 12 Lipid Metabolism -- Chapter 13 Photosynthesis -- Chapter 14 Nitrogen Metabolism I: Synthesis -- Chapter 15 Nitrogen Metabolism I: Degradation -- Chapter 16 Integration of Metabolism -- Chapter 17 Nucleic Acids -- Chapter 18 Genetic Information -- Chapter 19 Protein Synthesis.…”
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349
A sex-disaggregated analysis of the prognostic value of lean type 2 diabetes mellitus in the adult population with acute myocardial infarction
Published 2025-02-01“…Cox regression model was constructed to investigate the associations of lean and non-lean T2DM phenotypes with mortality, adjusted for age, ethnicity, previous AMI, AMI type, chronic kidney disease, angiotensin converting enzyme inhibitor or angiotensin receptor blockers, beta-blockers, and smoking status. …”
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350
Impact of donor CYP3A5 genotype on pharmacokinetics of tacrolimus in South African paediatric liver transplant patients
Published 2024-04-01“…The rs776746 polymorphism, CYP3A5*3, results in a splice defect and a non-functional enzyme. Clinically, to reach the same tacrolimus concentration-to-dose ratio (CDR), expressors (CYP3A5*1/*1 and *1/*3) require a higher tacrolimus dose than non-expressors (*3/*3). …”
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351
miR124a-3p inhibitor alleviates AFB1-induced hepatoxicity via targeting chicken glucocorticoid receptor mRNA
Published 2025-03-01“…Liver oxidative stress enzymes superoxide dismutase (SOD) and catalase (CAT) decreased significantly. …”
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352
Ginsenoside Rg1 alleviates chronic testicular damage caused by cranial irradiation through the SCF/PI3K/Akt/mTOR pathway in mice
Published 2025-02-01“…Further Terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling (TUNEL) and Enzyme linked immunosorbent assay (ELISA) assays demonstrated that Rg1 inhibited testicular apoptosis (IR: 3.21 ± 0.28 vs. …”
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353
Identification of novel pQTL‐SNPs associated with lung adenocarcinoma risk: A multi‐stage study
Published 2024-09-01“…The associations between selected pQTL‐SNPs and LUAD risk were evaluated by Female Lung Cancer Consortium in Asia GWAS (FLCCA GWAS). Enzyme linked immunosorbent assay (ELISA) is used to determine the levels of candidate protein. …”
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354
Nymphaea pubescens Willd. extract and its flavonoid constituents vasodilate rat isolated pulmonary artery via NO-sGC-cGMP pathway
Published 2025-02-01“…PAH treatment focuses on inducing PA vasodilation by inhibiting phosphodiesterase 5 (PDE5), the enzyme prominently expressed in pulmonary vasculature. …”
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355
A multistage drug delivery approach for colorectal primary tumors and lymph node metastases
Published 2025-02-01“…Thus, effective non-invasive methods to treat metastatic LNs would be highly desirable. Here, we develop an enzyme-responsive formulation of small-sized doxorubicin-loaded mesoporous silica nanoparticles (DMSN, 40 nm) encapsulated in nanoliposomes (DMSN@Pla-Lipo, 160 nm). …”
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356
The effects of citral on the intestinal health and growth performance of American bullfrogs (Aquarana catesbeiana)
Published 2025-02-01“…Optimal doses of 2–4 mL/kg also enhanced digestive enzyme activities, with α-amylase, lipase, and pepsin activities showing significant increases compared to the control group (P < 0.05). …”
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357
Evaluating the effects of dietary glutamine on performance, carcass traits, blood biochemistry, and intestine morphology in laying quail
Published 2025-03-01“…Glucose and creatinine levels varied with Gln supplementation and between the two time points; enzyme activities (alanine transaminase, alkaline phosphatase, and gamma-glutamyl transpeptidase) were affected by both Gln dose and length of supplementation. …”
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358
FDFT1 inhibits macrophage M1 polarization and promotes colorectal cancer progression
Published 2025-02-01“…Objective To screen the targets related to the metabolic enzymes involved in the cholesterol synthesis pathway that inhibits the polarization of macrophages towards M1 phenotype, and verify the intervention effects and underlying mechanisms in colorectal cancer cells. …”
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359
Effect of soil-groundwater system on migration and transformation of organochlorine pesticides: A review
Published 2025-01-01“…This paper focuses on two major sources of OCPs in soil and groundwater environments, compiles and summarizes the effects of environmental factors such as pH, microbial communities and enzyme activities on the transport and transformation of OCPs in soil and groundwater systems, discusses the synergistic effects of individual environmental factors and others, and comprehensively analyses the effects of synergistic effects of various environmental factors on the transport and transformation of OCPs. …”
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360
Liver damage in patients living with HIV on antiretroviral treatment with normal baseline liver function and without HBV/HCV infection: an 11-year retrospective cohort study in Gua...
Published 2019-04-01“…The association between duration of ART and liver damage (grade II–IV liver enzyme elevation [LEE] and/or total bilirubin elevation [TBE]), was analysed. …”
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