Immunological efficiency of Haemophilus influenzae type b polyribosyl ribitol phosphate combined with detoxified lipooligosaccharide in a rabbit model by Amin Arsang, Seyed Davar Siadat, Masoumeh Saberpour, Farshad Nojoomi

“…Serum samples were acquired on days 0, 14, and 28 post-immunization, then IgM and IgG levels were assayed by enzyme-linked immunosorbent assay. Results: The concentrations of PRP, dLOS, and endotoxin were 1160 mg/L, 440 μg/mL, and 1450 EU/mL, respectively. …”
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The Impacts of Breakthrough Drug Classes on Total Healthcare Expenditures by Zeynal Karaca, Steven N. Wiggins

“…We examined six different groups of breakthrough drugs, selective serotonin reuptake inhibitors, statins, angiotensin-converting-enzyme (ACE) inhibitors, histamine type 2 antagonists, proton pump inhibitors, calcium channel blockers and fluoroquinolones. …”
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Digestion, faeces microbiome, and selected blood parameters in dogs fed extruded food containing Black soldier fly (Hermetia illucens) meal by Kanber Kara, Oğuzhan Kahraman, Fatma İnal, Zekeriya Safa İnanç, Sena Yilmaz Öztaş, M. Selçuk Alataş, Ibrar Ahmed

“…As a result, HI larva meal can be used up to 100% instead of chicken meal in extruded dog food without any negative effects on body weight, digestibility, faecal score, consumption preference, kidney-liver enzyme activities and immunological parameters. Besides, HI larva meal at 7.5% and 15% in extruded dog food had different effects on the faecal microbiome.…”
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Manganese biofortification in grapevine by foliar spraying improves volatile profiles of Cabernet Sauvignon grapes and wine sensory traits by Ruihua Ren, Miaomiao Wang, Lijian Zhang, Fuxian Ren, Bowei Yang, Huangzhao Chen, Zhenwen Zhang, Qingqing Zeng

“…Manganese (Mn) is involved in plant metabolism as an enzyme cofactor. However, the role of Mn in the formation of volatile compounds in grapes has rarely been studied. …”
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Matrix metalloproteinase-3 is a potent prognostic factor associated with cell proliferation and migration in prostate cancer by Ai Sato, Kiyoshi Takagi, Mio Yamaguchi-Tanaka, Jotaro Okushima, Yuto Yamazaki, Akihiro Ito, Takashi Suzuki

“…Matrix metalloproteinase-3 (MMP3) is an enzyme that degrades several ECM components and is implicated in human malignancies. …”
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Scurvy as a Cause of Leg Pain and Limp in Pediatric and Adolescent Patients by Christopher J. DeFrancesco, MD, David Kell, BA, Sean Owens, BS, Matt Grady, MD, Naomi Brown, MD

“…Vitamin C deficiency (VCD) results in collagen dysfunction due to decreased lysyl and prolyl hydroxylase enzyme activity. The resulting disease, known as scurvy, can present with various findings, including gingival bleeding, bruising, other skin lesions, poor wound healing, and tooth and bone abnormalities. …”
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Nanobody-thioesterase chimeras to specifically target protein palmitoylation by Chien-Wen Kuo, Caglar Gök, Hannah Fulton, Eleanor Dickson-Murray, Samuel Adu, Emily K. Gallen, Sheon Mary, Alan D. Robertson, Fiona Jordan, Emma Dunning, William Mullen, Godfrey L. Smith, William Fuller

“…We conclude that nanobody enzyme chimeras represent an approach to specifically manipulate PTMs, with applications in both the laboratory and the clinic.…”
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Combination of Gilbert's syndrome and gastrointestinal diseases by G. M. Dubrovina, O. K. Botvinyev, A. I. Kolotilina

“…Mutation of encoding gene — A (TA) 7TAA A is the principal cause of insufficiency of this enzyme, however development of clinical syndrome and severity of symptoms is related to other factors as well (male gender, additional genetic mutations, et al.). …”
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Monoclonal anti-CD38 therapy in human myeloma: retrospects and prospects by Alberto L. Horenstein, Angelo C. Faini, Angelo C. Faini, Fabio Morandi, Erika Ortolan, Paola Storti, Nicola Giuliani, Nicola Giuliani, Paul G. Richardson, Fabio Malavasi, Fabio Malavasi

“…Despite CD38’s still central role in MM therapy, too little attention has been paid to its broader roles–not only as a myeloma marker but also as an enzyme and adhesion molecule in physiology. This review, a collaborative effort between basic scientists and clinical experts, explores some of the lesser-known mechanisms of antibody action and interactions with CD38 at key stages of treatment. …”
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Mediterranean diet improves liver health but does not protect against azoxymethane-induced colon tumorigenesis compared to Western diet in A/J mice by Weimin Guo, Nicholas Crossland, Jimmy W. Crott

“…At the end of the study hepatic Cyp2E1, an enzyme that metabolize AOM, was lower in males than females. …”
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Optimization of Enzymatic Hydrolysis Process, Structural Characterization and Antioxidant Activity Analysis of Gastrodia elata Polysaccharide by Yunfei HU, De ZHOU, Qinglan ZENG, Jinsong HE, Ming ZHAO, Qingyan TANG

“…Results revealed that the optimal enzymolysis process was as follows: enzyme dosage, 460 U/g, enzymolysis time, 100 min, enzymolysis temperature, 60 ℃, enzymolysis pH, 5.4. …”
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Eating Habits, Anxiety and Depression in Patients with Irritable Bowel Syndrome: Clinical and Laboratory Comparisons by O. V. Gaus, M. A. Livzan

“…All individuals included in the study were assessed for diet and eating habits using the WHO CINDI program questionnaire, “Information on Nutrition and Eating Behavior”, the severity of anxiety and depression according to the HADS questionnaire, the level of specific anxiety in relation to gastrointestinal symptoms according to the VSI questionnaire, quality of life according to the IBS-QoL questionnaire. In addition, the enzyme immunoassay method was used to assess the levels of cortisol in the morning and evening portions of saliva, serotonin in the blood serum and dopamine in the blood plasma.Results. …”
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Progress Analysis and Development Prospects of Soil Ecological and Environmental Effects of Interlayer Construction by JIA Zhenjiang, WU Yangyang, LI Wangcheng, MA Dongxiang, CHEN Jihong, GAO Susu, NIU Xiaoxiao, XU Tianyuan

“…[Methods] The effects and regulation mechanisms of interlayer construction on soil physical structure, soil water-salt-heat, soil nutrient status, soil enzyme activities, soil microbial properties, and crop productivity were comprehensively addressed. …”
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Grape stems as sources of tryptophan and selenium: Functional properties and antioxidant potential by Raquel Fernandes, Concepción Medrano-Padial, Rui Dias-Costa, Raúl Domínguez-Perles, Cláudia Botelho, Rúben Fernandes, Ana Novo Barros

“…Tryptophan, selenium, and phenolic compounds, which regulate cognitive functions, protein and enzyme synthesis, and antioxidant processes, were analysed. …”
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Hepatoprotective Effects of Nasturtium Officinale and Allium Polyanthum Extracts on CCL4- Induced Hepatic Damage In Albino Rats by Shkar Rzgar K.Rostam, Zana Hassan Ibrahim, Rebaz Rebwar Mala, Soran Qadir Abdul

“…Results: CCl4-treated rats were showed significant increase (p < 0.05) in the levels of serum enzyme activities (AST, ALT, & ALP), TSB and MDA; reflecting the hepatocellular damage caused by CCl4 compared with NC rats, whereas   the levels of TP and ALB were decreased. …”
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Modifiable life style factors and male reproductive health: a cross-sectional study in IVF clinic attendees in Ghana by Brodrick Yeboah Amoah, Saliah Yao Bayamina, Cosmos Gborsong, Hubert Owusu, George Awuku Asare, Emmanuel Kwabena Yeboah, Josephine Ablakwa, Georgina Hammond

“…Hormonal profiles (LH, FSH, testosterone, estradiol) were measured using the enzyme-linked fluorescent assay (ELFA). Statistical analyses included Pearson's product-moment correlation and Bonferroni correction.ResultsSmoking and psychological stress were significantly associated with reduced sperm motility, viability, and concentration (p &lt; 0.05). …”
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Promising LOX proteins for cartilage-targeting osteoarthritis therapy by Luca Morici, Eric Allémann, Olivier Jordan, Ines Nikolić

“…Finally, lysyl oxidase and lysyl oxidase-like are enzymes expressed intracellularly (in chondrocytes' cytoplasm) involved in elastin biosynthesis and collagen cross-linking in cartilage extracellular matrix. …”
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Identification of meibomian gland testosterone metabolites produced by tissue-intrinsic intracrine deactivation activity by Khanh Tien Nguyen Pham, Takahito Miyake, Tomo Suzuki, Shigeru Kinoshita, Yuki Hamada, Hikari Uehara, Mamiko Machida, Takeshi Nakajima, Emi Hasegawa, Masao Doi

“…Here, we performed radioactive tracer studies in combination with pharmacological enzyme inhibition, followed by targeted liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis, and found three androgen metabolites—androstanedione, androsterone, and epiandrosterone—in mouse and human meibomian glands. …”
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Biodegradability of Cellulose Fibers, Films, and Particles: A Review by Martin A. Hubbe, Jesse S. Daystar, Richard A. Venditti, Joel J. Pawlak, Marielis C. Zambrano, Morton Barlaz, Mary Ankeny, Steven Pires

“…Although cellulose is subject to well-known enzyme-promoted mechanisms of biodegradation, the evolution of plant materials has favored development of some resistance to decay, i.e. recalcitrance. …”
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