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421
Fractional-Order PI Control of First Order Plants with Guaranteed Time Specifications
Published 2013-01-01“…Because CSs contain both primitive cells and committed progenitors for the three major cell types present in the heart, that is, cardiomyocytes, endothelial cells, and smooth muscle cells, and because they are derived from percutaneous endomyocardial biopsies, they represent an attractive cell source for cardiac regeneration. …”
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422
Bifidobacterium fermentation with infant formulas is associated with benefits for gut and brain barrier function
Published 2025-02-01“…Cell-free supernatants from these fermentations were exposed to cultures of T84 colonocytes (gut barrier model) or bEnd.3 brain endothelial cells (BBB model), with and without lipopolysaccharide challenge. …”
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423
Semaphorin-4D signaling in recruiting dental stem cells for vascular stabilization
Published 2025-01-01“…Abstract Background Achieving a stable vasculature is crucial for tissue regeneration. Endothelial cells initiate vascular morphogenesis, followed by mural cells that stabilize new vessels. …”
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424
Virus Infection-Induced Bronchial Asthma Exacerbation
Published 2012-01-01“…Viral infections affect the barrier function of the airway epithelial cells and vascular endothelial cells. Recent reports have demonstrated augmented viral production mediated by an impaired interferon response in the airway epithelial cells of asthma patients. …”
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425
Disulfidptosis as a key regulator of glioblastoma progression and immune cell impairment
Published 2025-01-01“…Single-cell analysis showed high disulfidptosis-Tex activity in endothelial cells. Memory T cell populations were linked to these genes. …”
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426
Involvement of HMGB1 in Resistance to Tumor Vessel-Targeted, Monoclonal Antibody-Based Immunotherapy
Published 2016-01-01“…We have demonstrated that targeting of tumor-derived endothelial cells with an anti-human CD31 monoclonal antibody in a human neuroblastoma model was unsuccessful due to a complex chain of events involving the participation of HMGB1. …”
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427
The Precapillary Segment of the Blood-Brain Barrier and Its Relation to Perivascular Drainage in Alzheimer's Disease and Small Vessel Disease.
Published 2009-01-01“…At capillaries protein transport is possible via receptor-mediated endocytosis through endothelial cells. At the arteries and veins the BBB is thicker and there is, under physiological conditions, no direct transport from the brain tissue to the blood or vice versa. …”
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428
Cytokine Immunopathogenesis of Enterovirus 71 Brain Stem Encephalitis
Published 2012-01-01“…EV71 replicates in leukocytes, endothelial cells, and dendritic cells resulting in the production of immune and inflammatory mediators that shape innate and acquired immune responses and the complications of disease. …”
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429
Hyaluronan Immobilized Polyurethane as a Blood Contacting Material
Published 2010-01-01“…Cytotoxicity analysis showed that the PU-HA films synthesized in this study were cytocompatible and could support human vein endothelial cells (HUVECs) adhesion and proliferation.…”
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430
Circulating Endothelial Microparticles in Diabetes Mellitus
Published 2010-01-01“…Endothelial Microparticles (EMPs) are small vesicles shed from activated or apoptotic endothelial cells and involved in cellular cross-talk. …”
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431
Regulation of Endothelial Adherens Junctions by Tyrosine Phosphorylation
Published 2015-01-01“…Endothelial cells form a semipermeable, regulated barrier that limits the passage of fluid, small molecules, and leukocytes between the bloodstream and the surrounding tissues. …”
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432
Involvement of Nitric Oxide in a Rat Model of Carrageenin-Induced Pleurisy
Published 2010-01-01“…L-arginine and NOC-18 reversed the proinflammatory effects of NO synthase inhibitors, perhaps by reducing the expression of adhesion molecules on endothelial cells. Thus, our results indicate that NO is involved in blunting—not enhancing—the inflammatory response.…”
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433
MBL Interferes with Endovascular Trophoblast Invasion in Pre-Eclampsia
Published 2012-01-01“…Our recent data indicate that decidual endothelial cells (DECs), covering the inner side of the spiral arteries, acquire the ability to synthesize C1q, which acts as a link between endovascular trophoblast and DECs favouring the process of vascular remodelling. …”
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434
Tumour Cell Lines HT-29 and FaDu Produce Proinflammatory Cytokines and Activate Neutrophils In Vitro: Possible Applications for Neutrophil-Based Antitumour Treatment
Published 2009-01-01“…Cross-talk between tumour cells and endothelial cells (ECs) is necessary for the accumulation of PMN around a tumour. …”
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435
Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation
Published 2012-01-01“…Although the exact mechanism through which NADPH oxidases (Nox’s) generate reactive oxygen species (ROS) is still not completely understood, it is widely considered that ROS accumulation is the cause of oxidative stress in endothelial cells. Increasing pieces of evidence strongly indicate the role for ROS in endothelial inflammation and dysfunction and subsequent development of atherosclerotic plaques, which are causes of various pathological cardiac events. …”
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436
Rosiglitazone Restores Endothelial Dysfunction in a Rat Model of Metabolic Syndrome through PPARγ- and PPARδ-Dependent Phosphorylation of Akt and eNOS
Published 2011-01-01“…Importantly, this effect was blocked by either inhibition of PPARγ or PPARδ. In cultured endothelial cells, acute treatment with rosiglitazone increased the phosphorylation of Akt and eNOS and the production of NO. …”
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437
Gradual Increase of High Mobility Group Protein B1 in the Lungs after the Onset of Acute Exacerbation of Idiopathic Pulmonary Fibrosis
Published 2011-01-01“…In the lung tissues of eight IPF patients autopsied after acute exacerbation, intense cytoplasmic staining for HMGB1 was observed in the alveolar epithelial cells in alveolar capillary augmented lesions, where the capillary endothelial cells remarkably reduced the expression of thrombomodulin, an intrinsic antagonist of HMGB1. …”
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438
Placental growth factor modulates endothelial NO production and exacerbates experimental hepatopulmonary syndrome
Published 2025-03-01“…In vitro, PlGF stimulation enhanced eNOS activity in human pulmonary microvascular endothelial cells, whereas PlGF knockdown led to a decrease. …”
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439
Systemic brain dissemination of glioblastoma requires transdifferentiation into endothelial-like cells via TGF-β-ALK1-Smad1/5 signaling
Published 2025-02-01“…Mechanistically, in addition to TGF-β-ALK5-Smad2/3 signaling, glioblastoma tumour cells also activate TGF-β-ALK1-Smad1/5 signaling – a mechanism previously thought to be limited to endothelial cells. Consequently, therapeutic targeting of TGF-β-ALK1-Smad1/5 activity impaired endothelialisation-driven glioblastoma progression. …”
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440
Lymphatic-derived oxysterols promote anti-tumor immunity and response to immunotherapy in melanoma
Published 2025-01-01“…We show in a lymphangiogenic murine melanoma that lymphatic endothelial cells (LECs) upregulate the enzyme Ch25h, which catalyzes the formation of 25-hydroxycholesterol (25-HC) from cholesterol and plays important roles in lipid metabolism, gene regulation, and immune activation. …”
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