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401
Predicting lung aging using scRNA-Seq data.
Published 2024-12-01“…Our results identified lung epithelial cells as the most significant predictors for non-smokers while lung endothelial cells led to the best chronological age prediction results for smokers.…”
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402
Mechanism for the Increased Permeability in Endothelial Monolayers Induced by Elastase
Published 1994-01-01“…Pretreatment of bovine pulmonary artery endothelial cells (BPAEC) with HNE(0-30 μg/ml) for 1 h produced a concentration dependent increase in 125I-albumin clearance. …”
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403
Autophagy in Immune-Related Renal Disease
Published 2019-01-01“…These two-way effects are observed in immune cells as well as renal resident cells, including podocytes, mesangial cells, tubular epithelial cells, and endothelial cells of the glomerular capillaries. Mounting evidence suggests that autophagy is implicated in the pathological process of various immune-related renal diseases (IRRDs) as well as the kidney that underwent transplantation. …”
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404
HMBG1 as a Driver of Inflammatory and Immune Processes in the Pathogenesis of Ocular Diseases
Published 2018-01-01“…This proinflammatory activity is considered to be important in the pathogenesis of a wide range of ocular diseases resulting from hemodynamic changes, presence of neovascular endothelial cells, secretion of intraocular immune factors or inflammation, and apoptosis of retinal cell layers. …”
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405
Macrophages Are Key Regulators of Stem Cells during Skeletal Muscle Regeneration and Diseases
Published 2019-01-01“…Muscle regeneration is a closely regulated process that involves a variety of cell types such as satellite cells, myofibers, fibroadipogenic progenitors, endothelial cells, and inflammatory cells. Among these different cell types, macrophages emerged as a central actor coordinating the different cellular interactions and biological processes. …”
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406
The Upregulation of IL-1β Induced by Cisplatin Triggers PI3K/AKT/MMP9 Pathway in Pericytes Mediating the Leakage of the Blood Labyrinth Barrier
Published 2025-01-01“…Mechanistically, CDDP triggered IL-1β release from endothelial cells. IL-1β promoted MMP9 secretion from pericytes via the PI3K/AKT pathway, leading to disruption of tight junctions. …”
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407
Chondroitin Sulphate-Chitosan Based Nanogels Loaded with Naringenin-β-Cyclodextrin Complex as Potential Tool for the Treatment of Diabetic Retinopathy: A Formulation Study
Published 2025-01-01“…Cytotoxicity and internalization were assessed in vitro using Human Umbilical Vein Endothelial Cells (HUVEC). The NAR/β-CD complex was prepared and evaluated for morphology, complexation efficiency, and solubility. …”
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408
In vivo monitoring of leukemia-niche interactions in a zebrafish xenograft model.
Published 2024-01-01“…Interactions of LCs with macrophages and endothelial cells could be quantitatively characterized. …”
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409
Receptor-Mediated Endocytosis and Brain Delivery of Therapeutic Biologics
Published 2013-01-01“…Transport of macromolecules across the blood-brain-barrier (BBB) requires both specific and nonspecific interactions between macromolecules and proteins/receptors expressed on the luminal and/or the abluminal surfaces of the brain capillary endothelial cells. Endocytosis and transcytosis play important roles in the distribution of macromolecules. …”
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410
MicroRNAs in Postischemic Vascular Repair
Published 2012-01-01“…First, we will describe the regulation and the expression of miRNAs in endothelial cells. Then, we will analyze the role of miRNAs in postischemic vascular repair. …”
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411
Pancreatic organogenesis mapped through space and time
Published 2025-01-01“…Signals from the mesenchyme, neurons, and endothelial cells instruct epithelial cell differentiation during pancreatic development. …”
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412
Free circulating ICAM-1 in serum and cerebrospinal fluid of HIV-1 infected patients correlate with TNF-α and blood-brain barrier damage
Published 1992-01-01“…We have recently reported that tumour necrosis factor-α (TNF-α) mediates active neural inflammation and blood-brain barrier damage in HIV-1 infection. Stimulation of endothelial cells by TNF-α induces the expression of intercellular adhesion molecule-1 (ICAM-1), which is an important early marker of immune activation and response. …”
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413
Immunopathology of Postprimary Tuberculosis: Increased T-Regulatory Cells and DEC-205-Positive Foamy Macrophages in Cavitary Lesions
Published 2011-01-01“…Sections of characteristic lesions of caseating granulomas, lipid pneumonia, and cavitary stages of postprimary disease were selected for immunohistochemical studies of macrophages, lymphocytes, endothelial cells, and mycobacterial antigens. A higher percentage of cells in lipid pneumonia (36.1%) and cavitary lesions (27.8%) were positive for the dendritic cell marker DEC-205, compared to granulomas (9.0%, P<.05). …”
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414
Proangiogenic Features of Mesenchymal Stem Cells and Their Therapeutic Applications
Published 2016-01-01“…Studies on cardiovascular diseases have demonstrated that transplanted MSCs could engraft at the injured sites and differentiate into cardiomyocytes and endothelial cells as well. Accordingly, several clinical trials using MSCs have been performed and revealed that MSCs may improve relevant clinical parameters in patients with vascular diseases. …”
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415
Indoxyl Sulfate-Induced Oxidative Stress, Mitochondrial Dysfunction, and Impaired Biogenesis Are Partly Protected by Vitamin C and N-Acetylcysteine
Published 2015-01-01“…In the context of human umbilical vein endothelial cells, we found that IS had a dose-dependent antiproliferative effect. …”
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416
Epithelioid Hemangioma of the Carpus Presenting as Aneurysmal Bone Cyst
Published 2025-01-01“…Epithelioid hemangioma is a rare neoplasm characterized by locally aggressive behavior and composed of small vessels lined by epithelioid endothelial cells. Its varied presentation poses diagnostic challenges because of its ability to mimic other tumors. …”
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417
Densely vascularized thick 3D tissue shows enhanced protein secretion constructed with intermittent positive pressure
Published 2025-02-01“…The present study investigated the effects of air-compressing intermittent positive pressure (IPP) on co-cultured mesenchymal stem cells and vascular endothelial cells and evaluated the potential of IPP-cultured cell sheets for transplantation therapy. …”
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418
The Crosstalk between Ovarian Cancer Stem Cell Niche and the Tumor Microenvironment
Published 2017-01-01“…These properties are associated with the capacity of CSCs to interact with different cells of the tumor microenvironment including mesenchymal stem cells, endothelial cells, immune cells, and fibroblasts, promoting cancer progression. …”
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419
Human Cardiospheres as a Source of Multipotent Stem and Progenitor Cells
Published 2013-01-01“…Because CSs contain both primitive cells and committed progenitors for the three major cell types present in the heart, that is, cardiomyocytes, endothelial cells, and smooth muscle cells, and because they are derived from percutaneous endomyocardial biopsies, they represent an attractive cell source for cardiac regeneration. …”
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420
Single-cell and spatial transcriptomics in endocrine research
Published 2024-02-01“…For instance, the pituitary gland comprises five types of pituitary hormone-producing cells as well as non-hormone-producing supporting cells, such as fibroblasts, endothelial cells, and folliculostellate cells. However, the functional roles of the interactions between hormone-producing and non-producing cells in the pituitary gland remain incompletely understood. …”
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