Inhibition of complement system-related gene ITGB2 attenuates epithelial–mesenchymal transition and inflammation in diabetic nephropathy by Jun Peng, Wenqi Zhao, Lu Zhou, Kun Ding

“…Abstract Purpose Emerging evidences have indicated a role of the complement system in the pathogenesis of diabetic nephropathy (DN). …”
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Global Research Trends and Focus on the Link Between Heart Failure and NLRP3 Inflammasome: A Bibliometric Analysis From 2010 to 2024 by Lian Y, Zhang H, Xing W, Li S, Lai X, Jia S, Shang J, Liu H

“…The acquired data were subsequently analyzed utilizing various visualization instruments, including Citespace, VOSviewer, Scimago Graphica, and Microsoft Office Excel 2021.Results: A total of 282 papers were included in the analysis, authored by 2,130 researchers from 500 institutions across 34 nations/regions. China emerged as a significant contributor to this field, producing the highest number of outputs. …”
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Tolerability and Effectiveness of Regorafenib Treatment in Patients with Unresectable Hepatocellular Carcinoma: Real-World Data from the United States by Finn RS, Iyer R, Kalman RS, Parikh ND, Cabrera R, Babajanyan S, Kaseb AO

“…The primary study endpoint was the frequency of documented treatment-emergent adverse events (TEAEs). Additional endpoints included overall survival and progression-free survival. …”
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Xiaohua Funing decoction ameliorates non-alcoholic fatty liver disease by modulating the gut microbiota and bile acids by Jindong Zhao, Jindong Zhao, Yan Li

“…IntroductionThe gut microbiota and bile acids (BAs) have emerged as factors involved in the development of non-alcoholic fatty liver disease (NAFLD). …”
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Validating a digital depression prevention program for adolescents in Jordan: cultural adaptation and user testing in a randomized controlled trial by Latefa Ali Dardas, Obada Al-leimon, Tracy Gladstone, Abd Arrahman Dabbas, Insaf Alammouri, Benjamin Van Voorhees

“…However, challenges such as limited access to personal devices, privacy concerns, and participants’ reliance on shared family resources emerged as significant barriers to consistent engagement. …”
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Perceived wildfire risk and past experiences with wildfire smoke influence public support for prescribed burning in the western conterminous United States by Christopher J Rogers, Celeste Beck, Rima Habre, Jo Kay Ghosh

“…Methods Data were from the May 2023 Household Emergency Preparedness Survey, an online panel survey of 1,727 adults in 12 western conterminous states, applying survey weights to reflect the underlying population demographics. …”
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Modeling factors related to earthquake preparedness: a structural equation modeling approach by Azadeh Fatehpanah, Elham Maraghi, Anthony Coetzer-Liversage, Mahmood Karimy, Amir H. Pakpour, Majed Maripour, Nematollah Jaafarzadeh Haghighi Fard, Marzieh Araban

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VGG-16, VGG-16 With Random Forest, Resnet50 With SVM, and EfficientNetB0 With XGBoost-Enhancing Bone Fracture Classification in X-Ray Using Deep Learning Models by Spoorthy Torne, Dasharathraj K. Shetty, Krishnamoorthi Makkithaya, Prasiddh Hegde, Manu Sudhi, Phani Kumar Pullela, T Tamil Eniyan, Ritesh Kamath, Staissy Salu, Pranav Bhat, S. Girisha, P. S. Priya

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ENTREPRENEURSHIP OF MEMORY IN PUBLIC SPACE AND SOCIAL COMMUNICATION: A POSTCOLONIAL APPROACH IN TIME OF WAR by Viktoriia Kovpak, Nataliia Lebid, Viktor Burenkov

“…In the context of the experience economy, memory entrepreneurship has emerged as a significant phenomenon during wartime. …”
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Ethnobotanical Survey and Conservation Strategies of Medicinal Plants Used in Masulita Sub-County in Wakiso District. by Musoke, Ronald

“…Gastrointestinal diseases (15.66%) were the most frequently treated ailments, and cultivation emerged as the primary conservation strategy. Eleven medicinal plant species were identified as scarce due to herbicide use and overexploitation. …”
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COVID-19-related stress, anxiety and vaccine hesitancy among healthcare workers in a tertiary hospital in South-Western Nigeria by Temitope Olumuyiwa Ojo, Tajudin Adesegun Adetunji, Stanley Chinedu Eneh, Baderinwa Opeyemi Akanji, Olusola Fajobi, Olanrewaju Elugbaju, Olanrewaju Ibikunle Ibigbami, Temilola Oladunmomi Owojuyigbe, Samuel Anu Olowookere, Olusegun Temitope Afolabi, Adedeji Ayodeji Onayade

“…Abstract COVID-19 ranks as one of the major pandemics in recent history, with healthcare workers disproportionately burdened by the disease. Vaccination emerged as the most effective measure to curb the spread and reduce COVID-19 morbidity and mortality. …”
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Spirituality-Based Intervention in Hypertension: EFfects on Blood PrEssure and EndotheliaL Function—FEEL Trial Results by Maria Emília Figueiredo Teixeira, Weimar Kunz Sebba Barroso, Andréa Araújo Brandão, Ana Luiza Lima Sousa, Roberto Esporcatte, Mário Henrique Elesbão de Borba, Ana Clara Neri Ávila Baleeiro, Beatriz Caldas Gonçalves, Enzo Inumaru, Enzo Mata de Sousa, Giovana Barros Leal, Henrique Soares de Araújo Pereira Farias, Juliana Alves de Souza, Lure Emilly Barreto da Silva, Matheus Canguçu de Paiva Queiroz, Frederico Rafael Moreira, Priscila Valverde de Oliveira Vitorino, John Eikelboom, Álvaro Avezum

“…Background: Emerging evidence suggests that spirituality improves patient outcomes, however, this has undergone only limited evaluation in randomized trials. …”
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TAME 2.0: expanding and improving online data science training for environmental health research by Alexis Payton, Alexis Payton, Alexis Payton, Elise Hickman, Elise Hickman, Elise Hickman, Jessie Chappel, Jessie Chappel, Jessie Chappel, Kyle Roell, Kyle Roell, Lauren E. Koval, Lauren E. Koval, Lauren A. Eaves, Lauren A. Eaves, Chloe K. Chou, Chloe K. Chou, Chloe K. Chou, Allison Spring, Allison Spring, Sarah L. Miller, Sarah L. Miller, Sarah L. Miller, Oyemwenosa N. Avenbuan, Oyemwenosa N. Avenbuan, Oyemwenosa N. Avenbuan, Rebecca Boyles, Rebecca Boyles, Paul Kruse, Cynthia V. Rider, Grace Patlewicz, Caroline Ring, Cavin Ward-Caviness, David M. Reif, Ilona Jaspers, Ilona Jaspers, Ilona Jaspers, Ilona Jaspers, Ilona Jaspers, Rebecca C. Fry, Rebecca C. Fry, Rebecca C. Fry, Julia E. Rager, Julia E. Rager, Julia E. Rager, Julia E. Rager

“…Training topics were prioritized based upon ongoing engagement with trainees, professional colleague feedback, and emerging topics in the field of environmental health research (e.g., artificial intelligence and machine learning). …”
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Investigating Confined Space Asphyxias: Plastic Bag Involvement and Gas Inhalation – A Case Series and Literature Review by Sofija Saulė Kaubrytė, Sigitas Chmieliauskas, Giedrė Kažukauskė, Sigitas Laima, Diana Vasiljevaitė, Jurgita Stasiūnienė

“…Results: Plastic bag suffocation, often combined with inert gas inhalation, emerges as a common method in suicides. Demographic analyses reveal distinct patterns, with younger age groups demonstrating an increased tendency for gas inhalation suicides. …”
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Temporal trends of the utilization patterns of sedative-hypnotic medications in children, adolescents and young adults: a 21-year population-based study with joinpoint regression a... by Carltin Chun Ting Kwok, Heidi Ka Ying Lo, Ching Yui Chan, Joe Kwun Nam Chan, Corine Sau Man Wong, Calvin Pak Wing Cheng, Chung Ho, Brian Man Ho Leung, Wilfred Shone Horn Wong, Zoe Hoi Shuen Yu, Edwin Ho Ming Lee, Wing Chung Chang

“…Anxiety and depression emerged as the most commonly-assigned diagnoses for BZRA-users. …”
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Carbon sequestration in different urban vegetation types in Southern Finland by L. Thölix, L. Backman, M. Havu, M. Havu, E. Karvinen, J. Soininen, J. Trémeau, O. Nevalainen, J. Ahongshangbam, L. Järvi, L. Järvi, L. Kulmala

“…However, the validation of the absolute level of modelled fluxes proved difficult due to differences in the scale of the observations and models, particularly for mature trees, and due to the fact that net ecosystem exchange measurements in urban areas include some anthropogenic emissions. Irrigation emerged as a key factor often improving carbon sequestration, while tree-covered areas demonstrated greater carbon sequestration rates compared to lawns on an annual scale. …”
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Study protocol of a pilot randomised controlled trial assessing the feasibility and acceptability of RecoverEsupport: a digital health intervention to enhance recovery in women und... by Christopher Oldmeadow, Mitch J Duncan, Penny Reeves, Priscilla Viana da Silva, Rebecca Wyse, Helen Moore, Alison Zucca, Sancha Robinson, Stephen Ridley Smith, Emma Sansalone, Owen Morris, Rebecca Chenery, Lara Riley, Anna Palazzi-Parsons

“…Data regarding patient behaviours related to patient-managed ERAS recommendations, Quality of Life, European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30), Quality of Recovery (QOR-15), Anxiety (Hospital Anxiety and Depression Scale), hospital readmissions, emergency department presentations and health service utilisation postdischarge will also be collected.Ethics and dissemination This study has been approved by the Human Research Ethics Committees of the Hunter New England Local Health District (2022/ETH02010), the University of Newcastle (H-2023–0298) and the Calvary Mater Newcastle (2022/STE03757). …”
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Electrochemotherapy with bleomycin, oxaliplatin, or cisplatin in mouse tumor models, from tumor ablation to in situ vaccination by Katja Uršič Valentinuzzi, Katja Uršič Valentinuzzi, Urška Kamenšek, Urška Kamenšek, Simona Kranjc Brezar, Chloe Heranney, Chloe Heranney, Tilen Komel, Tilen Komel, Simon Buček, Simon Buček, Maja Čemažar, Maja Čemažar, Gregor Serša, Gregor Serša

“…By evaluating ECT’s potential for in situ vaccination, our goal was to pave the way for future advancements for its combination with emerging (immuno)therapies, leading to enhanced responses and outcomes.MethodsWe employed two mouse tumor models, the immunologically cold B16F10 melanoma and 4T1 mammary carcinoma, to explore both local and systemic (i.e., abscopal) antitumor effects following equieffective intratumoral ECT with BLM, OXA, and CDDP. …”
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A randomized, double-blind, Phase 1, single- and multiple-dose placebo-controlled study of the safety and pharmacokinetics of IN-006, an inhaled antibody treatment for COVID-19 in... by Thomas R. Moench, Lakshmi Botta, Brian Farrer, Jason D. Lickliter, Hyunah Kang, Yoona Park, Cheolmin Kim, Marshall Hoke, Miles Brennan, Morgan D. McSweeney, Zachary Richardson, John B. Whelan, Jong Moon Cho, Soo Young Lee, Frances Faurot, Jeff Hutchins, Samuel K. Lai

“…All enrolled participants completed the study without treatment interruption or discontinuation. All treatment-emergent adverse events were transient, non-dose dependent, and graded mild to moderate in severity. …”
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Association between glyphosate exposure and cardiovascular health using “Life’s Essential 8” metrics in US adults by Yuankang Zhu, Zhenlin Yang, Yuhao Chen, Lingzi Qian, Changning Hao, Liangshi Hao, Boshen Yang, Junli Duan

“…A non-linear relationship between glyphosate and total CVH emerged (p for non-linear<0.001, p for overall = 0.003), and no safe threshold of glyphosate was observed. …”
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