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321
The Role of SUMO1 Modification of SOX9 in Cartilage Development Stimulated by Zinc Ions in Mice
Published 2025-12-01“…Subsequently, we subjected the embryos to scrutiny employing HE, Safranin O staining and IHC. …”
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322
Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway
Published 2025-02-01“…By transiently blocking the heartbeat of E9.5 mouse embryos, we found that Notch activation in the arterial endothelium was dependent on its ligand Dll4, whereas the reduced expression of Dll4 in the endocardium led to a ligand-depleted field, enabling Notch to be specifically activated in AVC and OFT by regional increased shear stress. …”
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323
RETRACTED: Environmental Risk Assessment of Dexamethasone Sodium Phosphate and Tocilizumab Mixture in Zebrafish Early Life Stage (<em>Danio rerio</em>)
Published 2022-05-01“…This study was aimed to evaluate the molecular pathway underling the developmental toxicity of exposure in the ecological environment. Zebrafish embryos were exposed at doses of dexamethasone sodium phosphate (DEX) 1 μmol/L, tocilizumab 442.1 μmol/L and dexamethasone + tocilizumab (1 μmol/L and 442.1 μmol/L, respectively) from 24 h post-fertilization (hpf) to 96 hpf. …”
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324
Immune imbalance in the pre-ovulatory follicular microenvironment of overweight and obese women during IVF
Published 2025-02-01“…Furthermore, day 3 high quality embryos rate is negatively associated with BMI and exhibits a decreasing trend in OW group. …”
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325
Dopamine receptors and key elements of the neurotrophins (BDNF, CDNF) expression patterns during critical periods of ontogenesis in the brain structures of mice with autism-like be...
Published 2024-07-01“…In this study, we investigated the expression of key dopamine receptors (Drd1, Drd2), brain-derived neurotrophic factor (Bdnf), its receptors (Ntrkb2, Ngfr) and the transcription factor Creb1 that mediates BDNF action, as well as cerebral dopamine neurotrophic factor (Cdnf) during the critical periods of embryogenesis (e14 and e18) and postnatal development (p14, p28, p60) in the hippocampus and frontal cortex of BTBR mice with autism-like behavior compared to the neurotypical C57BL/6 J strain. In BTBR embryos, on the 14th day of prenatal development, an increase in the expression of the Ngfr gene encoding the p75NTR receptor, which may lead to the activation of apoptosis, was found in the hippocampus and frontal cortex. …”
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326
Parental conflicts and resource sharing: Evolutionary trade-off
Published 2025-02-01“…There is a hypothetical scenario in which parents can influence gene expression in embryos directly. Similar to genomic imprinting, this may happen as a result of sexual selection in males competing with other males to gain more resources for their offspring from their mothers. …”
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327
Assessing molecular changes underlying isopropylated phenyl phosphate (IPP)-induced larval sensorimotor response deficits in zebrafish
Published 2025-01-01“…Within this study, we used zebrafish embryos to systemically study these biological targets. …”
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328
Evaluation of developmental competence of Sus scrofa domesticus (L.) oocyte-cumulus complexes after intra- and extraovarian vitrification
Published 2021-10-01“…The methods of fertilization and embryo culture are presented in the guidelines developed by us. …”
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329
Manifestation of agronomically valuable traits in the progeny of a sorghum mutant carrying the genetic construct for RNA silencing of the γ-kafirin gene
Published 2024-03-01“…Using Agrobacterium-mediated genetic transformation of immature embryos of the grain sorghum cv. Avans we have obtained a mutant with improved digestibility of endosperm proteins (up to 92 %) carrying a genetic construct for RNA silencing of the gKAF1 gene. …”
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330
Controlled ovarian hyperstimulation with or without letrozole for fertility preservation in breast cancer patients: study protocol for a randomised controlled trial
Published 2025-01-01“…The standard options for fertility preservation are oocyte and embryo cryopreservation; both require controlled ovarian hyperstimulation (COH). …”
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331
Comparison of Endocrine Profile and In Vitro Fertilization Outcome in Patients with PCOS, Ovulatory PCO, or Normal Ovaries
Published 2012-01-01“…The basic clinical features and in vitro fertilization and embryo transfer outcome in patients receiving IVF or intracytoplasmic sperm injection (ICSI) were retrospectively analyzed. …”
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332
Single-cell sequencing provides clues about the developmental genetic basis of evolutionary adaptations in syngnathid fishes
Published 2025-02-01“…We created a single-cell RNA sequencing atlas of Gulf pipefish embryos to understand the developmental basis of four traits: derived head shape, toothlessness, dermal armor, and male pregnancy. …”
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333
In Vitro and In Ovo Evaluation of <i>Oenothera biennis</i> L. Oil as an Alternative Preservative for Oil-Based Products
Published 2025-01-01“…Various methods were applied to assess oxidative stability by calculating the peroxide value, the <i>p</i>-anisidine value, and the total oxidation value, while biological safety was evaluated using the chick embryo’s chorioallantoic membrane and histological analysis. …”
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334
The potential for gene-editing to increase muscle growth in pigs: experiences with editing myostatin
Published 2022-06-01“…One male and one female cell line with a deletion of one thymidine residue (− 1 T) were selected for somatic cell nuclear transfer. Of the ~ 900 embryos transferred, there were 12 live births (1 male, 11 females) but only 5 female pigs survived to sexual maturity. …”
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335
Three-dimensional diffractive acoustic tomography
Published 2025-01-01“…Using 3D-DAT on small animal models, we mapped the distribution of the biliverdin-binding serpin complex in glassfrogs, tracked gold nanoparticle accumulation in a mouse tumor model, imaged genetically-encoded photoswitchable tumors, and investigated polyfluoroalkyl substances exposure on developing embryos. With its enhanced imaging performance and high accessibility, 3D-DAT may find broad applications in fundamental life sciences and biomedical research.…”
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336
Ochratoxin A induces immunotoxicity by targeting Annexin A1 mediated neutrophil apoptosis in zebrafish
Published 2025-01-01“…However, limited understanding exists regarding its immunotoxicity and the underlying mechanisms, particularly in relation to innate immunity.MethodsZebrafish embryos were exposed to varying concentrations of OTA to assess its impact on embryonic development, innate immune cell formation, and immune response. …”
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337
Research note: Establishment of a multiplex PCR detection system for different infectious bronchitis virus strain genotypes in laying hens
Published 2025-01-01“…It was subsequently applied to the identification of purposefully randomly mixed infections of two, three, four or five IBV strains mentioned above in samples of chicken embryos. All of the intentionally infected samples showed the expected amplified bands. …”
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338
Molecular identification of Newcastle disease virus isolated on the poultry farm of the Moscow Oblast in summer of 2022
Published 2023-06-01“…It was found that the average death time of developing chicken embryos, infected with a minimum infectious dose, was 52 hours, which is typical for the velogenic pathotype. …”
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339
Targeted genome modifcation in protoplasts of a highly regenerable Siberian barley cultivar using RNA-guided Cas9 endonuclease
Published 2019-01-01“…In the present study, an evaluation of in vitro regeneration efciency of immature embryos of ten Siberian barley cultivars revealed that only one of these is on a par with the experimental standard cultivar Golden Promise. …”
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340
Prediction of Reproductive Outcomes of Intracytoplasmic Sperm Injection Cycles Using a Multivariate Scoring System
Published 2024-01-01“…Women who have a low score have a high chance of having frozen embryos. Likewise, women who have a high score have a very high chance of cycle cancellation. …”
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