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Candidate SNP-markers altering TBP binding affinity for promoters of the Y-linked genes CDY2A, SHOX, and ZFY are lowering many indexes of reproductive potential in men
Published 2020-12-01“…., SHOX: rs1452787381) and even for embryogenesis disorders (e. g., SHOX: rs28378830). This indicates a wide range of MRI indicators, alterations in which should be expected in the case of SNPs in the promoters of the human Y-chromosome genes and which can go far beyond changes in male fertility.…”
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102
Expression pattern of lncRNA H19 in oral squamous cell carcinoma tissues in comparison to normal tissues. A systematic review
Published 2025-03-01“…A key factor in cancer biology, the long non-coding RNA H19 was first discovered for its function in embryogenesis. H19, reactivated in cancers, interacts with microRNAs and signaling pathways such as p53 and PI3K/AKT to affect tumor growth, invasion, and metastasis. …”
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103
Expression of the NUP153 and YWHAB genes from their canonical promoters and alternative promoters of the LINE-1 retrotransposon in the placenta of the first trimester of pregnancy
Published 2023-03-01“…Thus, the observed increase in the LINE-1 methylation index in the placenta of spontaneous abortions is associated with the level of expression of the NUP153 and YWHAB genes not only from alternative but also from canonical promoters, which can subsequently lead to negative consequences for normal embryogenesis.…”
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104
Histopathological Characterization and Whole Exome Sequencing of Ectopic Thyroid: Fetal Architecture in a Functional Ectopic Gland from Adult Patient
Published 2018-01-01“…Ectopic thyroid results from a migration defect of the developing gland during embryogenesis causing congenital hypothyroidism. But it has also been detected in asymptomatic individuals. …”
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105
Overexpression of the <i>GmPM35</i> Gene Significantly Enhances Drought Tolerance in Transgenic Arabidopsis and Soybean
Published 2025-01-01“…Merr.) yield. Late embryogenesis abundant protein (LEA protein) is a large family of proteins widely distributed in various types of organisms, and this class of proteins plays an important role in protecting proteins, membrane lipids, and lipids inside the cell. …”
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