The N-terminus of the Chlamydia trachomatis effector Tarp engages the host Hippo pathway by George F. Aranjuez, Om Patel, Dev Patel, Travis J. Jewett

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Multivariate quantitative analysis of glycan impact on IgG1 effector functions by Tamara Cvijić, Matej Horvat, Jakob Plahutnik, Ana Golob, Jaka Marušič

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THE ROLE OF GENETICALLY DETERMINED BODY RESISTANCE OF WARM-BLOODED ANIMALS TO HYPOXIA IN THE REALIZATION OF EFFECTOR FUNCTIONS OF NEUTROPHILS IN THE MODEL OF ADJUVANT-INDUCED RHEUM... by Elena Georgievna Pukhaeva, Alibek Kirilovich Badtiev, Fatima Elbrusovna Salamova, Stanislav Georgievich Dzgoev, Alina Muratbekovna Kupeeva

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Impact of Vaccine-Elicited Anti-Spike IgG4 Antibodies on Fc-Effector Functions Against SARS-CoV-2 by Katrina Dionne, Alexandra Tauzin, Étienne Bélanger, Yann Desfossés, Mehdi Benlarbi, Ling Niu, Guillaume Beaudoin-Bussières, Halima Medjahed, Catherine Bourassa, Josée Perreault, Marzena Pazgier, Renée Bazin, Andrés Finzi

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Tuning antibody stability and function by rational designs of framework mutations by Joseph C. F. Ng, Alicia Chenoweth, Maria Laura De Sciscio, Melanie Grandits, Anthony Cheung, Tooki Chu, Alexandra McCraw, Jitesh Chauhan, Yi Liu, Dongjun Guo, Semil Patel, Alice Kosmider, Daniela Iancu, Sophia N. Karagiannis, Franca Fraternali

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Evaluating the immune effector functions induced by humanized anti-CD99 antibody in eliminating T lymphoblastic leukemia/lymphoma cells by Kamonporn Kotemul, Ratthakorn Chaiwut, Chaochetdhapada Putpim, Supansa Pata, Witida Laopajon, Chatchai Tayapiwatana, Watchara Kasinrerk, Nuchjira Takheaw

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A whole blood-based functional assay to characterize immunoglobulin A effector functions by Alice Bacon, Celia Cartagena García, Karin A. van Schie, René E. M. Toes, Jean-Marc Busnel

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Non-neutralizing monoclonal antibody targeting VP2 EF loop of Coxsackievirus A16 can protect mice from lethal attack via Fc-dependent effector mechanism by Ruixiao Du, Chaoqiang An, Xin Yao, Yiping Wang, Ge Wang, Fan Gao, Lianlian Bian, Yalin Hu, Siyuan Liu, Qiaohui Zhao, Qunying Mao, Zhenglun Liang

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High‐resolution definition of humoral immune response correlates of effective immunity against HIV by Galit Alter, Karen G Dowell, Eric P Brown, Todd J Suscovich, Anastassia Mikhailova, Alison E Mahan, Bruce D Walker, Falk Nimmerjahn, Chris Bailey‐Kellogg, Margaret E Ackerman

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With great power, comes great responsibility: the importance of broadly measuring Fc-mediated effector function early in the antibody development process by Silvia Crescioli, Shashi Jatiani, Lenny Moise

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Cancer therapy via neoepitope-specific monoclonal antibody cocktails by Colin J. Hartman, Asmaa O. Mohamed, Girja S. Shukla, Stephanie C. Pero, Yu-Jing Sun, Roberto S. Rodríguez-Jimenez, Nicholas F. Genovese, Nico M. Kohler, Thomas R. Hemphill, Yina H. Huang, David N. Krag, Margaret E. Ackerman

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Antibody Fab‐Fc properties outperform titer in predictive models of SIV vaccine‐induced protection by Srivamshi Pittala, Kenneth Bagley, Jennifer A Schwartz, Eric P Brown, Joshua A Weiner, Ilia J Prado, Wenlei Zhang, Rong Xu, Ayuko Ota‐Setlik, Ranajit Pal, Xiaoying Shen, Charles Beck, Guido Ferrari, George K Lewis, Celia C LaBranche, David C Montefiori, Georgia D Tomaras, Galit Alter, Mario Roederer, Timothy R Fouts, Margaret E Ackerman, Chris Bailey‐Kellogg

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Tensor‐structured decomposition improves systems serology analysis by Zhixin Cyrillus Tan, Madeleine C Murphy, Hakan S Alpay, Scott D Taylor, Aaron S Meyer

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The microbial metabolite butyrate enhances the effector and memory functions of murine CD8+ T cells and improves anti-tumor activity by Douglas A. Gaskarth, Shujun Fan, Andrew J. Highton, Roslyn A. Kemp

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Coronavac inactivated vaccine triggers durable, cross-reactive Fc-mediated phagocytosis activities by Lili Wang, Chuang Li, Wanting Li, Liwei Zhao, Tiantian Zhao, Lin Chen, Ming Li, Jing Fan, Jiayan Li, Chao Wu, Yuxin Chen

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Impact of antibody Fc engineering on translational pharmacology, and safety: insights from industry case studies by Frank R. Brennan, J. Ryan Polli, Jean Sathish, Melissa Ramones, Babette Wolf, Tilman Schlothauer, Shirley J. Peters, Curtis C. Maier, Changhua Ji, David L. Wensel, Derrick Witcher, Patricia C. Ryan, T. Scott Manetz, Adriano Flora, Brian Soper, Birgit Fogal, Lindsey Dzielak, Xiaoting Wang, Prathap Nagaraja Shastri, Karen Price, Michael Doyle, Nidhi Sharda, Mary Struthers, Maximilian Brinkhaus, Bianca Balbino, Eric Stefanich, Masaki Honda, Jan Terje Andersen, Shermaine Mitchell-Ryan, David P. Humphreys

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CoronaVac-induced antibodies that facilitate Fc-mediated neutrophil phagocytosis track with COVID-19 disease resolution by Chuang Li, Jie Yu, Rahma Issa, Lili Wang, Mingzhe Ning, Shengxia Yin, Jie Li, Chao Wu, Yuxin Chen

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Dose-dependent serological profiling of AdCLD-CoV19-1 vaccine in adults by Jung Hyuk Lee, Yuna Shin, Kwang-Soo Shin, Ju Yeon Park, Mi Sun Kim, Young-Shin Park, Wuhyun Kim, Joon Young Song, Ji Yun Noh, Hee Jin Cheong, Chang-Yuil Kang, Sang Hwan Seo, Jae-Ouk Kim, Deok Ryun Kim, Nathaniel S. Hwang, Jae Seung Yang, Jerome H. Kim, Byoung-Shik Shim, Manki Song

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Vγ9Vδ2 T cells expanded with vitamin C combined with HMBPP in vitro inhibit intracellular Mycobacterium tuberculosis growth by Shuyan Liu, Shuyan Liu, Guohui Xiao, Wanxin Liang, Su Zhang, Juan Liang, Teng Pan, Shaoxiang Lin, Xiuju Liu, Zhenwen Zhou, Guoliang Zhang

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Therapeutic efficacy of a potent anti-Venezuelan equine encephalitis virus antibody is contingent on Fc effector function by Jennifer L. Schwedler, Maxwell A. Stefan, Christine E. Thatcher, Peter R. McIlroy, Anupama Sinha, Ashlee M. Phillips, Christopher A. Sumner, Colleen M. Courtney, Christina Y. Kim, Dina R. Weilhammer, Brooke Harmon

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