Corrigendum: D-dencichine regulates thrombopoiesis by promoting megakaryocyte adhesion, migration and proplatelet formation by Shilan Ding, Shilan Ding, Shilan Ding, Shilan Ding, Min Wang, Min Wang, Min Wang, Min Wang, Song Fang, Huibo Xu, Huiting Fan, Yu Tian, Yu Tian, Yu Tian, Yu Tian, Yadong Zhai, Yadong Zhai, Yadong Zhai, Yadong Zhai, Shan Lu, Shan Lu, Shan Lu, Shan Lu, Xin Qi, Fei Wei, Fei Wei, Fei Wei, Fei Wei, Guibo Sun, Guibo Sun, Guibo Sun, Guibo Sun, Xiaobo Sun, Xiaobo Sun, Xiaobo Sun, Xiaobo Sun

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Decorin, an exercise-induced secretory protein, is associated with improved prognosis in breast cancer patients but does not mediate anti-tumorigenic tissue crosstalk in mice by Marit Hjorth, Casey L. Egan, Guilherme D. Telles, Martin Pal, David Gallego-Ortega, Oliver K. Fuller, Emma D. McLennan, Ryan D. Gillis, Tae Gyu Oh, George E.O. Muscat, Surafel Tegegne, Michael S.M. Mah, Joanna Skhinas, Emma Estevez, Timothy E. Adams, Matthew J. McKay, Mark Molloy, Kevin I. Watt, Hongwei Qian, Paul Gregorevic, Thomas R. Cox, Pernille Hojman, Julie Midtgaard, Jesper F. Christensen, Martin Friedrichsen, Renato V. Iozzo, Erica K. Sloan, Brian G. Drew, Jørgen F.P. Wojtaszewski, Martin Whitham, Mark A. Febbraio

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Trafficked Proteins—Druggable in Plasmodium falciparum? by Jasmin Lindner, Kamila Anna Meissner, Isolmar Schettert, Carsten Wrenger

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Designing of an innovative conserved multiepitope subunit vaccine targeting SARS-CoV-2 glycoprotein and nucleoprotein through immunoinformatic by Temitope Isaac Adelusi, Abdeen Tunde Ogunlana, Moyosoluwa Precious Oyewole, Taiwo Ooreoluwa Ojo, Olamide Tosin Olaoba, Elijah Kolawole Oladipo, Shopnil Akash, Samir Ibenmoussa, Mohammed Bourhia, Yousef A. Bin Jardan, Baye Sitotaw

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iDICss robustly predicts melanoma immunotherapy response by synergizing genomic and transcriptomic knowledge via independent component analysis by Jiayue Qiu, Nana Jin, Lixin Cheng, Chen Huang

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Electrochemical Behavior of Biologically Important Indole Derivatives by Cigdem Karaaslan, Sibel Suzen

“…Use of electrochemistry is an important approach in drug discovery and research as well as quality control, drug stability, and determination of physiological activity. …”
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Corrigendum to “Influenza and the risk of active tuberculosis occurrence among individuals with latent tuberculosis infection: A national cohort study in South Korea (2015–2020)” [... by Jaehee Lee, Hyewon Seo, Dohyang Kim, Jinseub Hwang, Jin-Won Kwon

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Structural basis of CXCR4 assembly and regulation by Aijun Liu, Yezhou Liu, Richard D. Ye

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Assessment of Acute and Chronic Pharmacological Effects on Energy Expenditure and Macronutrient Oxidation in Humans: Responses to Ephedrine by Antonella Napolitano, Peter R. Murgatroyd, Nick Finer, Elizabeth K. Hussey, Robert Dobbins, Steve O'Rahilly, Derek J. R. Nunez

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Time-resolved compositional and dynamics analysis of biofilm maturation and dispersal via solid-state NMR spectroscopy by Yi Xue, Xue Kang

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Coronil effectively inhibits the interaction of clinically relevant Omicron mutants of SARS-CoV-2 spike proteins with human ACE2 receptor by Acharya Balkrishna, Rishabh Dev, Sandeep Kumar, Anurag Varshney

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AiGPro: a multi-tasks model for profiling of GPCRs for agonist and antagonist by Rahul Brahma, Sunghyun Moon, Jae-Min Shin, Kwang-Hwi Cho

“…Abstract G protein-coupled receptors (GPCRs) play vital roles in various physiological processes, making them attractive drug discovery targets. Meanwhile, deep learning techniques have revolutionized drug discovery by facilitating efficient tools for expediting the identification and optimization of ligands. …”
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Metabolic and epigenetic regulation of macrophage polarization in atherosclerosis: Molecular mechanisms and targeted therapies by Pinglian Yang, Xiaoling Rong, Zhechang Gao, Jiaojiao Wang, Zhiping Liu

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Diversity-oriented synthesis of stereodefined tetrasubstituted alkenes via a modular alkyne gem-addition strategy by Xuan Di, Sitian Zhou, Yali Qin, Wenjun Li, Yue Zhang, Jie Zhang, Xu Shen, Jie Han, Jin Xie, Hongming Jin

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Clinical Symptoms and Types of Samples Are Critical Factors for the Molecular Diagnosis of Symptomatic COVID-19 Patients: A Systematic Literature Review by Milad Zandi, Abbas Farahani, Armin Zakeri, Sara Akhavan Rezayat, Ramin Mohammadi, Umashankar Das, Jonathan R. Dimmock, Shervin Afzali, Mohammadvala Ashtar Nakhaei, Alireza Doroudi, Yousef Erfani, Saber Soltani

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Slow Metabolism–Driven Amplification of Hepatic PPARγ Agonism Mediates Benzbromarone‐Induced Obesity‐Specific Liver Injury by Guanting Li, Yourong Hu, Han Zhao, Ziyu Peng, Xin Shang, Jia Zhang, Kunxin Xie, Meiwei Li, Xiaohang Zhou, Qinyao Zhou, Kai Li, Fang Zhou, Heyao Wang, Zhijian Xu, Jiali Liu, Peng Sun

“…Given the significance of BBR and its analogs in anti‐gout/hyperuricemia drug discovery, elucidating the mechanism by which BBR exacerbates obesity‐specific DILI warrants further investigation. …”
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Bioactive compounds and probiotics–a ray of hope in COVID-19 management by Indu Bhushan, Mahima Sharma, Malvika Mehta, Shivi Badyal, Varun Sharma, Indu Sharma, Hemender Singh, Srinivas Sistla

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A microscale thermophoresis-based enzymatic RNA methyltransferase assay enables the discovery of DNMT2 inhibitors by Zarina Nidoieva, Mark O. Sabin, Tristan Dewald, Annabelle C. Weldert, Sabrina N. Hoba, Mark Helm, Fabian Barthels

“…Abstract RNA methyltransferases (MTases) have recently become increasingly important in drug discovery. Yet, most frequently utilized RNA MTase assays are limited in their throughput and hamper this rapidly evolving field of medicinal chemistry. …”
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Fully automated CFD simulation system research based on design scheme tree by Zijun Liu

“…Abstract Compared with the remarkable achievements of computer-aided drug discovery systems for drug discovery, the role of computational fluid dynamics (CFD) in flow channel design requires further development. …”
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Isolation of MDCK cells with low expression of mdr1 gene and their use in membrane permeability screening by BOKULIĆ ANA, PADOVAN JASNA, STUPIN-POLANČEC DARIJA, MILIĆ ASTRID

“…The Madin-Darby canine kidney (MDCK) cell line is frequently used for permeability screening in drug discovery. It contains endogenous transporters, most prominently canine multidrug resistance P-glycoprotein (Mdr1), which can interfere with studies of P-glycoprotein substrate assessment and permeability measurements. …”
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