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761
Balloon dilation for the treatment of male urethral strictures: a systematic review and meta-analysis
Published 2024-02-01“…The balloon is a promising drug delivery tool, and paclitaxel drug-coated balloon dilation is effective in reducing retreatment rates in patients with recurrent anterior urethral strictures. …”
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762
A Comprehensive Review on Current Knowledge and Future Potential of Topical Therapies in Breast Cancer Treatment
Published 2025-01-01“…Recently, topical drug delivery is transforming breast cancer therapy, offering precision and reduced systemic toxicity. …”
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763
Interfacing exogenous stents with human coronary artery by self-assembled coating: designs, functionalities and applications
Published 2024-05-01“…Moreover, we discuss the potential of self-assembled coatings for future development, including intelligent targeted drug delivery, bionic stent coatings, and 3D printed stent coatings. …”
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764
Development, Optimization, and Stability Study of a Yataprasen Film-Forming Spray for Musculoskeletal Pain Management
Published 2025-01-01“…The FFS shares similarities with gel formulations, particularly in its ability to form a cohesive, semi-solid film upon application, enhancing localized drug delivery and prolonged contact time. Key physicochemical properties, including density (0.8450–0.9086 g/cm<sup>3</sup>), pH (4.72–4.95), spray angle (55.58–60.10°), evaporation time (1.04–1.27 min), and theoretical film thickness (7.72–13.97 µm), were analyzed across varying storage conditions. …”
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765
Development and Optimization of Nano-Hydroxyapatite Encapsulating Tocotrienol-Rich Fraction Formulation Using Response Surface Methodology
Published 2024-12-01“…Recently, the nano-hydroxyapatite (nHA) has been investigated as a drug delivery vehicle for various drugs and active compounds owing to its excellent biocompatibility, biodegradability, and osteogenic properties. …”
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766
Evolution of Alzheimer’s Disease Therapeutics: From Conventional Drugs to Medicinal Plants, Immunotherapy, Microbiotherapy and Nanotherapy
Published 2025-01-01“…Furthermore, the therapeutic potential of emerging approaches, such as the use of microRNAs to regulate key cellular processes and nanotherapy, which enables precise drug delivery to the central nervous system, is analyzed. …”
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767
Improving dexamethasone drug loading and efficacy in treating rheumatoid arthritis via liposome: Focusing on inflammation and molecular mechanisms
Published 2025-01-01“…This study investigates the potential of liposomal drug delivery systems to enhance the efficacy and targeting of DEX in the treatment of RA. …”
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768
Synergistic Antibacterial Action of Norfloxacin-Encapsulated G4 Hydrogels: The Role of Boronic Acid and Cyclodextrin
Published 2025-01-01“…The most effective hydrogel displayed an inhibition zone of 25 mm in disk diffusion assays, and was further explored as a drug delivery platform, with the aim to exploit the capacity of the free <i>β</i>-CD cavity of the hydrogels to incorporate hydrophobic drugs. …”
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769
Melanoma extracellular vesicles membrane coated nanoparticles as targeted delivery carriers for tumor and lungs
Published 2025-02-01“…Targeting is the most challenging problem to solve for drug delivery systems. Despite the use of targeting units such as antibodies, peptides and proteins to increase their penetration in tumors the amount of therapeutics that reach the target is very small, even with the use of nanoparticles (NPs). …”
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770
Multicentre, prospective, randomised controlled trial to evaluate hexaminolevulinate photodynamic therapy (Cevira) as a novel treatment in patients with high-grade squamous intraep...
Published 2022-06-01“…APRICITY is a multicentre, prospective, double-blind, randomised controlled phase 3 study further evaluating the efficacy and safety of Cevira, an integrated drug-delivery and light-delivery device for hexaminolevulinate photodynamic therapy, which shows promise as a novel, non-invasive outpatient therapy for women with HSIL.Methods and analysis Patients with biopsy-confirmed HSIL histology are invited to participate in the study planned to be conducted at 47 sites in China and 25 sites in Ukraine, Russia and the European Union. …”
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771
Antifungal efficacy of chitosan-mediated fenugreek nanocomposite incorporated in tissue conditioner
Published 2025-03-01“…Combining fenugreek extract with chitosan, can further improve antifungal outcomes due to its excellent drug delivery, mucoadhesive properties, and bioavailability. …”
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772
Advances in Pure Drug Self-Assembled Nanosystems: A Novel Strategy for Combined Cancer Therapy
Published 2025-01-01“…Nanoparticle-based drug delivery systems hold great promise for improving the effectiveness of anti-tumor therapies. …”
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773
Wearable electrodriven switch actively delivers macromolecular drugs to fundus in non-invasive and controllable manners
Published 2025-01-01“…The WES system, which integrates an electrodriven drug delivery lens with a square wave generator, leverages electrical stimulation to enhance drug penetration through the sclera-choroid-retina pathway. …”
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774
Engineered Perfluorochemical Cancer-Derived Exosomes Loaded with Indocyanine Green and Camptothecin Provide Targeted Photochemotherapy for Effective Cancer Treatment
Published 2025-01-01“…Yu-Hsiang Lee,1– 3 Cheng-You Huang1 1Department of Biomedical Sciences and Engineering, National Central University, Taoyuan City, Taiwan, Republic of China; 2Department of Chemical and Materials Engineering, National Central University, Taoyuan City, Taiwan, Republic of China; 3Department of Medical Research, Cathay General Hospital, Taipei City, Taiwan, Republic of ChinaCorrespondence: Yu-Hsiang Lee, Department of Biomedical Sciences and Engineering, National Central University, No. 300, Jhongda Road, Taoyuan City, 320317, Taiwan, Republic of China, Tel +886-3-422-7151 Ext# 27755, Fax +886-3-280-4627, Email yuhsianl@ncu.edu.twBackground: Cancer treatments are still limited by various challenges, such as off-target drug delivery, posttreatment inflammation, and the hypoxic conditions in the tumor microenvironment; thus, the development of effective therapeutics remains highly desirable. …”
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775
High-Performance Liquid Chromatography Assay for Moxifloxacin in Brain Tissue and Plasma: Validation in a Pharmacokinetic Study in a Murine Model of Cerebral Listeriosis
Published 2012-01-01“…This study was based on single-drug delivery, intravenously dosed in a central listeriosis murine model. …”
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776
A computational role of blood nanofluid induced by a stenosed artery with porous medium and thermophoretic particle deposition effects
Published 2025-02-01“…This investigation is motivated by the potential of the Casson nanofluids, which exhibit exceptional thermal properties, offering promising applications in medical treatments such as targeted drug delivery and hyperthermia therapy. The present work focuses on understanding the flow behavior of the Casson nanofluids through the stenosed artery under the influence of porosity, thermal radiation, thermophoretic particle diffusion and Stefen blowing. …”
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777
Risk Factors of Noncompliance to Preventive Mass Drug Administration for Eliminating Lymphatic Filariasis: A Case-Control Study in Jawi District, Northwest Ethiopia
Published 2022-01-01“…Noncompliance with lymphatic filariasis mass drug administration therapy was associated with specific demographic, individual, program, and drug delivery characteristics. This finding has important implications for program effectiveness and would be used to accelerate the elimination of lymphatic filariasis in the study area and other endemic settings.…”
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778
Baicalin Liposome Alleviates Lipopolysaccharide-Induced Acute Lung Injury in Mice via Inhibiting TLR4/JNK/ERK/NF-κB Pathway
Published 2020-01-01“…Hence, we prepared a novel drug delivery system—Baicalin liposome (BA-LP) in previous research—which can improve some physical properties of BA. …”
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779
The Role of Pentacyclic Triterpenoids in Non-Small Cell Lung Cancer: The Mechanisms of Action and Therapeutic Potential
Published 2024-12-01“…Furthermore, advances in drug delivery technologies such as nanocarriers and targeted delivery systems have improved the bioavailability and therapeutic efficacy of triterpenoids. …”
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780
In situ template synthesized silver nanoparticulate banana fibre materials with antimicrobial and antibiotic release properties: Efficacy evaluation in ex vivo wound infection mode...
Published 2025-01-01“…These findings establish BF-SNP, BFS-SNP, and BFM-SNP as promising candidates for antimicrobial wound care applications and controlled drug delivery systems, offering a sustainable, bioresource-based solution for advanced biomedical materials.…”
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