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741
Superparamagnetic Bifunctional Bisphosphonates Nanoparticles: A Potential MRI Contrast Agent for Osteoporosis Therapy and Diagnostic
Published 2010-01-01“…A bone targeting nanosystem is reported here which combined magnetic contrast agent for Magnetic Resonance Imaging (MRI) and a therapeutic agent (bisphosphonates) into one drug delivery system. This new targeting nanoplatform consists of superparamagnetic γFe2O3 nanoparticles conjugated to 1,5-dihydroxy-1,5,5-tris-phosphono-pentyl-phosphonic acid (di-HMBPs) molecules with a bisphosphonate function at the outer of the nanoparticle surface for bone targeting. …”
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742
Hydrogel-Based Innovations in Carpal Tunnel Syndrome: Bridging Pathophysiological Complexities and Translational Therapeutic Gaps
Published 2025-01-01“…Their ability to mimic the extracellular matrix facilitates localized drug delivery, anti-adhesion barrier formation, and tissue regeneration. …”
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743
Oxidative stress in diabetes mellitus and its complications: From pathophysiology to therapeutic strategies
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744
Three-Dimensional Printable Magnetic Hydrogels with Adjustable Stiffness and Adhesion for Magnetic Actuation and Magnetic Hyperthermia Applications
Published 2025-01-01“…Stimuli-responsive hydrogels hold immense promise for biomedical applications, but conventional gelation processes often struggle to achieve the precision and complexity required for advanced functionalities such as soft robotics, targeted drug delivery, and tissue engineering. This study introduces a class of 3D-printable magnetic hydrogels with tunable stiffness, adhesion, and magnetic responsiveness, prepared through a simple and efficient “one-pot” method. …”
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745
Investigations of Long-Acting Formulations in Children, Adolescents, and Pregnant Women: A Systematic Review
Published 2025-01-01“…<b>Background/Objectives:</b> Long-acting and extended-release drug delivery strategies have greatly improved treatment for a variety of medical conditions. …”
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746
Biocompatible and Biodegradable Ultrafine Nanoparticles of Poly(Methyl Methacrylate-co-Methacrylic Acid) Prepared via Semicontinuous Heterophase Polymerization: Kinetics and Produc...
Published 2016-01-01“…Because of their biocompatibility and biodegradability as well as their extremely small size these nanoparticles could be used as vehicles for improved drug delivery in the treatment of chronic-degenerative diseases.…”
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747
Luminescence enhancement of Y2O3:Er3+ and Y2O3:Yb3+/Er3+ sub-microcrystals by Zr4+ ions Co-doping
Published 2025-06-01“…This research contributes to the understanding of UC luminescent properties of lanthanide (Ln3+) ions doped UC materials and their technological applications in fields such as bioimaging, drug delivery, and optical temperature sensors.…”
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748
In situ delivery of synthetic preimplantation factor using aldehyde-modified hyaluronic acid hydrogel with immobilized complexes of chondroitin sulfate derivatives
Published 2025-03-01“…This study presents an injectable drug delivery system (DDS) using 2 % (w/v) aldehyde-modified hyaluronic acid (HAOX) and chondroitin sulfate (CSOX) to deliver 100 µg of Fluorescein isothiocyanate-modified SPIF (FITC-SPIF). …”
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749
Identification of a Novel Anticancer Oligopeptide from Perilla frutescens (L.) Britt. and Its Enhanced Anticancer Effect by Targeted Nanoparticles In Vitro
Published 2018-01-01“…This study is aimed at identifying cytotoxic oligopeptides which are loaded by a drug delivery system, to explore its anticancer application. …”
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750
Development and in vitro evaluation of biomimetic injectable hydrogels from decellularized human nerves for central nervous system regeneration
Published 2025-04-01“…Overall, iHPN is a novel injectable hydrogel that has potential for minimally invasive CNS applications, such as a carrier for cell or drug delivery and/or a biomaterial to support axonal growth.…”
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751
Optimising Palm Olein-Based Betamethasone 17-Valerate Emulsions for Scalable Manufacturing and Stability
Published 2025-01-01“…Despite its potential as a topical drug delivery vehicle, the practical implementation of manufacturing 20% (w/w) palm olein-in-water emulsions for commercial purposes has not been explored extensively, and obtaining experimental data on scale-up studies would be helpful in facilitating this realisation. …”
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752
Natural products targeting RAS by multiple mechanisms and its therapeutic potential in cancer: An update since 2020
Published 2025-02-01“…Strategies such as combination therapy, structural optimization, and drug delivery systems are anticipated to enhance efficacy and overcome these challenges.…”
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753
Nanoemulsified Butenafine for Enhanced Performance against Experimental Cutaneous Leishmaniasis
Published 2021-01-01“…Based on the leishmanicidal activity of butenafine chloride and considering the absence of reports about the therapeutic potential of this drug in cutaneous leishmaniasis, the present work is aimed at analyzing the efficacy of butenafine formulated in two different topical delivery systems, the self-nanoemulsifying drug delivery systems (BUT-SNEDDS) and in a SNEDDS-based nanogel (BUT-SNEDDS gel) as well as in the free form in experimental cutaneous leishmaniasis. …”
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754
Exploring the Structural Diversity and Biotechnological Potential of the Rhodophyte Phycolectome
Published 2024-12-01“…Moreover, their diversity enables biotechnological exploration as biomarkers, biosensors, drug-delivery platforms, and lead molecules for anticancer, antidiabetic, and antimicrobial drugs. …”
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755
Peptide Aptamer–Paclitaxel Conjugates for Tumor Targeted Therapy
Published 2024-12-01“…By harnessing the unique properties of peptide aptamers, these conjugates demonstrate significant promise in improving drug delivery efficiency while reducing the adverse effects associated with traditional paclitaxel therapy. …”
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756
Mathematical Modelling of Acetaminophen Release in HPC/PAAm Hydrogel: Synthesis and Application
Published 2019-01-01“…Hydrogels are commonly used as Drug Delivery Systems (DDS) as patches due to its ability to store drug molecules within their structures. …”
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757
RETRACTED: Mycosynthesis of Hematite (α-Fe<sub>2</sub>O<sub>3</sub>) Nanoparticles Using <em>Aspergillus niger</em> and Their Antimicrobial and Photocatalytic Activities
Published 2022-08-01“…Nanoparticles (NPs) and nanomaterials (NMs) are now widely used in a variety of applications, including medicine, solar energy, drug delivery, water treatment, and pollution detection. …”
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758
ANFIS-PSO analysis on axisymmetric tetra hybrid nanofluid flow of Cu-CNT-Graphene-Tio2 with WEG-Blood under linear thermal radiation and inclined magnetic field: A bio-medicine app...
Published 2025-01-01“…The hybrid fluid of Cu-CNT + Graphene + TiO2/WEG-Blood, which is subject to heat transfer in a channel between two parallel plates with an angled magnetic field and linear thermal radiation, has numerous applications in engineering, industry, and biomedical research, such as electronic cooling, drug delivery, cancer treatment, optics, missiles, satellites, transformer-electronic cooling, and military solar-equipment. …”
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759
Development of Spray-Dried Micelles, Liposomes, and Solid Lipid Nanoparticles for Enhanced Stability
Published 2025-01-01“…<b>Objectives:</b> Micelles, liposomes, and solid lipid nanoparticles (SLNs) are promising drug delivery vehicles; however, poor aqueous stability requires post-processing drying methods for maintaining long-term stability. …”
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760
CAR-T therapy for endocrine neoplasms: novel targets and combination of therapies
Published 2025-02-01Get full text
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