A global Corynebacterium diphtheriae genomic framework sheds light on current diphtheria reemergence by Hennart, Mélanie, Crestani, Chiara, Bridel, Sébastien, Armatys, Nathalie, Brémont, Sylvie, Carmi-Leroy, Annick, Landier, Annie, Passet, Virginie, Fonteneau, Laure, Vaux, Sophie, Toubiana, Julie, Badell, Edgar, Brisse, Sylvain

Subjects: “…diphtheria, genomic sequencing, antimicrobial resistance, virulence, epidemiology, transmission, 2022 reemergence, bioinformatics tool…”
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Diphtheria case detection and carrier study of close contacts: A step towards diphtheria eradication by Shilpa R. Shah, Nisha C. Karanje

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Changes in TNF and IL-6 production after diphtheria toxoid vaccination: drug modulation of the cytokine levels by A. L. Pukhalsky, M. S. Bliacher, A. V. Danilina, E. A. Kalashnikova, T. K. Lopatina, I. M. Fedorova

“…The effect of vaccination with diphtheria toxoid (AD-M) on TNF and IL-6 production has been studied in humans. …”
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Toksigenitas Corynebacterium diphtheriae Pada Sampel Kejadian Luar Biasa Difteri Tahun 2010 – 2015 Menggunakan Elektes by Kambang Sariadji, Sunarno Sunarno

“…Strain Corynebacterium diphtheriae dapat dibedakan berdasarkan sifat toksigenisitas atau kemampuannya dalam memproduksi toksin difteri. …”
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A Cost-Effective Epidemiological Exposition of Diphtheria Outbreak by the Optimal Control Model: A Case Study of Rohingya Refugee Camp in Bangladesh by Zahurul Islam, K. M. Ariful Kabir, M. M. Rahman, Md. Atikur Rahman

“…We consider a deterministic optimal control approach with cost-effectiveness analysis for the diphtheria outbreak in the Rohingya refugee camp in Bangladesh. …”
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The Peptide Vaccine Combined with Prior Immunization of a Conventional Diphtheria-Tetanus Toxoid Vaccine Induced Amyloid β Binding Antibodies on Cynomolgus Monkeys and Guinea Pigs by Akira Yano, Kaori Ito, Yoshikatsu Miwa, Yoshito Kanazawa, Akiko Chiba, Yutaka Iigo, Yoshinori Kashimoto, Akira Kanda, Shinji Murata, Mitsuhiro Makino

“…We previously reported that the Aβ peptide vaccine including the T-cell epitope of diphtheria-tetanus combined toxoid (DT) induced anti-Aβ antibodies, and the prior immunization with conventional DT vaccine enhanced the immunogenicity of the peptide. …”
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Mapping C. difficile TcdB interactions with host cell-surface and intracellular factors using proximity-dependent biotinylation labeling by Jennifer S. Ward, Karl J. Schreiber, John Tam, Ji-Young Youn, Roman A. Melnyk

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Pertussis Vaccination for Adults: An Updated Guide for Clinicians by Kay Choong See

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What do Parents Learn by Reading a DPT Vaccine Information Form? by Ronald Gold, Gordean L Bjornson

“…This study assessed the knowledge of mothers about pertussis and pertussis vaccine before and after reading a form about diphtheria-pertussis-tetanus (dpt) vaccine.…”
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Subglottic stenosis as a presentation of various rheumatic diseases by Bhavya Chintala, Lalit Duggal, Neeraj Jain, Mayank Gupta

“…Other causes are tracheal infections including bacterial tracheitis, tuberculosis, histoplasmosis and diphtheria, and collagen vascular diseases including granulomatosis with polyangiitis, relapsing polychondritis, etc., SGS may be a presenting complaint in rheumatological disorder. …”
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Population-Based Surveillance of HiB Invasive Infections in Children in British Columbia, Alberta and Ontario -- 1995 to 1997 by David Scheifele, Alison Bell, Taj Jadavji, Wendy Vaudry, John Waters, Monika Naus, Jill Sciberras

“…OBJECTIVE: To assess vaccine effectiveness through enhanced disease surveillance following the change in childhood immunization programs in 1995, when all provinces and territories chose to use polyribosyl ribitol phosphate-tetanus protein (PRP-T) Haemophilus influenzae type b (Hib) conjugate vaccine, generally in combination with diphtheria-pertussis-tetanus inactivated polio vaccine (DPT-IPV) (as PENTA vaccine) because the protective efficacy of this regimen had not been directly measured.…”
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Immunological Links to Nonspecific Effects of DTwP and BCG Vaccines on Infant Mortality by Mogens Helweg Claesson

“…A number of mainly observational studies suggest that many African females below the age of one year die each year from the nonspecific effects of vaccination with diphtheria-tetanus toxoids and killed (whole-cell) Bordetella pertussis (DTwP). …”
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Repeated Long-Term DT Application in the DEREG Mouse Induces a Neutralizing Anti-DT Antibody Response by Junhua Wang, Myriam Siffert, Markus Spiliotis, Bruno Gottstein

“…In DEREG mice, Foxp3+ Tregs selectively express enhanced green fluorescent protein (eGFP) and diphtheria toxin (DT) receptor, allowing for the specific depletion of Tregs through DT administration. …”
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Routine Immunization of Adults in Canada: Review of the Epidemiology of Vaccine-Preventable Diseases and Current Recommendations for Primary Prevention by Michael D Parkins, Shelly A McNeil, Kevin B Laupland

“…All Canadians, irrespective of age, should have immunity to measles, mumps, rubella, tetanus, diphtheria, pertussis and varicella. All adult Canadians with significant medical comorbidities or those older than 65 years of age should receive the pneumococcal polysaccharide vaccine and yearly trivalent inactivate influenza vaccines. …”
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Convalescent plasma therapy in severe coronavirus disease-2019: A narrative review by Rasmi Ranjan Sahoo, Kasturi Hazarika, Prashant Bafna, Manesh Manoj, Anupam Wakhlu

“…Much before, the concept of transfusing neutralizing antibodies through convalescent blood or plasma was established; this modality demonstrated its effectiveness in containing the havoc caused by diphtheria and tetanus during the early 20th century. …”
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BNT162b2 Vaccination during Pregnancy Protects Both the Mother and Infant: Anti-SARS-CoV-2 S Antibodies Persistently Positive in an Infant at 6 Months of Age by Chetna Mangat, Natasa Milosavljevic

“…Other vaccines, such as influenza and Tdap (tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis) vaccines, provide significant protection for babies. …”
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Vaccination Coverage of the Elderly in Greece: A Cross-Sectional Nationwide Study by Dimitrios Papagiannis, Georgios Rachiotis, Anargiros Mariolis, Efterpi Zafiriou, Konstantinos I. Gourgoulianis

“…In addition, the vaccination coverage for herpes zoster vaccine was 20%, while very low percentages were recorded for diphtheria, tetanus, pertussis, and polio vaccine for adults. …”
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Interleukin-1 Receptor-Associated Kinase 4 Deficiency in a Greek Teenager by Panagiota Karananou, Anastasia Alataki, Efimia Papadopoulou-Alataki

“…She was able to make functional antibodies against vaccine antigens, including tetanus and diphtheria. She was administered with empirical IgG substitution for 5 years until the age of 12 years, and she has never experienced invasive bacterial infections so far. …”
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Vaccination status of individuals with diabetes mellitus treated in Primary Healthcare: a cross-sectional study by Francisco João de Carvalho Neto, Luisa Helena de Oliveira Lima, Mônica Antar Gamba, Rosilane Lima de Brito, Lucilane Maria Sales da Silva, Ana Roberta Vilarouca da Silva

“…Results among individuals with diabetes mellitus, the following incomplete vaccination rates were found: 69.1% for hepatitis B; 64.6% for diphtheria and tetanus; 74.3% for yellow fever; 87.9% for pneumococcus; 87.9% for varicella; 24.5% for influenza; and 0.7% for COVID-19. …”
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Fibrocyte enrichment and myofibroblastic adaptation causes nucleus pulposus fibrosis and associates with disc degeneration severity by Yi Sun, Yan Peng, Zezhuo Su, Kyle, K. H. So, Qiuji Lu, Maojiang Lyu, Jianwei Zuo, Yongcan Huang, Zhiping Guan, Kenneth M. C. Cheung, Zhaomin Zheng, Xintao Zhang, Victor Y. L. Leung

“…Depleting the fibrocytes in CD11b-DTR mice in which myeloid-derived lineages were ablated by diphtheria toxin could markedly attenuate fibrous modeling and myofibroblast formation in the NP of the degenerative discs, and prevent disc height loss and histomorphological abnormalities. …”
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