Design and Mechanism Study of 6c, a Novel Artesunate Derivatives, for Anti-Hepatocellular Carcinoma by Xiong SS

“…Molecular docking shows the binding of 6c compound to oncogenic vascular endothelial growth factor receptor 2 (VEGFR-2) and Transferrin receptor protein 1 (TFR1) that are overexpressed in malignant epithelial tumors.Conclusion: Taken together, our identification of the promising compound 6c may hold developmental potential for therapy of hepatocellular carcinoma. …”
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Effect of Chromatin-Remodeling Agents in Hepatic Differentiation of Rat Bone Marrow-Derived Mesenchymal Stem Cells In Vitro and In Vivo by Danna Ye, Tong Li, Philip Heraud, Rangsun Parnpai

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Cumulus cell expansion, nuclear maturation and embryonic development of bovine cumulus-oocyte complexes matured in varying concentrations of follicular fluid. by Verónica M Negrón-Pérez, Abdullah Al Naib, Abigail L Zezeski, Victoria L McCracken-Harlow, George A Perry, Alan D Ealy, Michelle L Rhoads

“…In general, FF supplementation at 50% did not affect the zygotes' developmental potential (neither increased nor decreased). …”
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Single-session upper limb plyometric training is as effective as two sessions for improving muscle strength, power, and serve velocity in male youth tennis players: a randomized pa... by Jian Wang, Qi Xu

“…A total of 47 male youth tennis players (15.6 ± 0.9 years), competing at the trained/developmental level, participated in the study. Evaluations were conducted twice—once before the intervention and once after—assessing isometric shoulder rotation strength (internal [ISRT] and external [ESRT]) with a dynamometer, the medicine ball chest throw (MBCT), seated shot-put test (SST), and serve velocity using a radar gun.ResultsIn the post-intervention, significant differences were observed between groups for the variables of ISRT (p = 0.010; ηp2 = 0.189), ESRT (p = 0.004; ηp2 = 0.226), MBCT (p = 0.012; ηp2 = 0.181), SST (p = 0.019; ηp2 = 0.164), and tennis serve velocity (p = 0.004; ηp2 = 0.226).ConclusionThe study found that ULPT significantly improves upper limb muscle strength, power, and serve velocity in young male tennis players, with both once and twice weekly training yielding similar benefits. …”
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Moments that matter: childhood pain treatment shapes pain for life—we can do better every time in every child by Rebeccah Slater, Suellen Walker, Christopher Eccleston, Carlo Bellieni, Tanvi Hirekodi, Ricardo Carbajal, Lucinda Smart, William Laughey, Maria M. Cobo, Stefan Friedrichsdorf

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Chromosome Numbers and Reproductive Life Cycles in Green Plants: A Phylotranscriptomic Perspective by Rijan R. Dhakal, Alex Harkess, Paul G. Wolf

“…We found expansions in gene families related to developmental regulation, signaling pathways, and stress responses across heterosporous groups. …”
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Models of Historical Memory and past Representation of Vilnius University in the 19th-20th Centuries by Alfredas Bumblauskas

“…On the other hand, the different developmental periods witnessed not the "pure" nationalistic models of historical memory - such as the "Polish", "Russian", "Lithuanian", as well as the communist model - but rather a compromise of different models. …”
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The Protective Role of Ambient Ultraviolet Radiation Against Dementia: An Ecological Analysis of Global Data by Wenpeng You

“…Subgroup analyses were performed to explore differences across income classifications, regional groupings, and developmental statuses, based on World Bank and United Nations criteria. …”
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Reversal of Experimental Liver Damage after Transplantation of Stem-Derived Cells Detected by FTIR Spectroscopy by Danna Ye, Philip Heraud, Rangsun Parnpai, Tong Li

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How does BMI correlate with menarche onset? Evidence from the Italian HBSC cross-sectional study by Domitilla Marconi, Dario Lipari, Andrea Pammolli, Paola Dalmasso, Paola Nardone, Alessio Vieno, Rita Simi, Giacomo Lazzeri

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Analysis of somatic piRNAs in the malaria mosquito Anopheles coluzzii reveals atypical classes of genic small RNAs by Sergei Funikov, Alexander Rezvykh, Natalia Akulenko, Jiangtao Liang, Igor V. Sharakhov, Alla Kalmykova

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Effects of Combined Application of Biogas Slurry and Chemical Fertilizers on Silage Corn, Soil Nutrients, and Microorganisms by Wencong Yang, Yijing Cheng, Xia Wu, Jia Zhou, Xiuping Liu

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Impact of the COVID-19 lockdown in the United Kingdom on adolescent's time use (CONTRAST study). by Irina Pokhilenko, Emma Frew, Marie Murphy, Miranda Pallan

“…Given that adolescence is a crucial developmental stage, designing strategies to alleviate the impact of the COVID-19 on adolescents is critical. …”
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An Open‐Label Phase II Trial of Pembrolizumab, an Immune Checkpoint Inhibitor Alone or in Combination With Oral Azacitidine as Second‐Line Therapy for Advanced Head and Neck Squamo... by Vinod K. Ramani, Srimonta Gayen, Radheshyam Naik

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Molecular characterization and functional annotation of a hypothetical protein (SCO0618) of A3(2) by Nadim Ferdous, Mahjerin Nasrin Reza, Md. Tabassum Hossain Emon, Md. Shariful Islam, A. K. M. Mohiuddin, Mohammad Uzzal Hossain

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Social Inequalities in Adolescents’ Psychological and Somatic Complaints: Cross-National Trends Between 2002 and 2022 and the Role of Societal Changes by Mathilde E. Brons, Paola Berchialla, Marco Helbich, Maxim Dierckens, Michela Lenzi, Joanna C. Inchley, Gonneke W. J. M. Stevens

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Recurrent Diplopia in a Pediatric Patient with Bickerstaff Brainstem Encephalitis by Scott A. McLeod, Wallace Wee, Francois D. Jacob, Isabelle Chapados, Francois V. Bolduc

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Investigating Light and Water Optimization for Early Seedling Establishment in Albizia lebbeck (L.) Benth by Kelechi Godwin Ibeh, Adejoke Olukemi Akinyele

“…Strong intrinsic synchronization was observed between the collar diameter and plant height growth trajectories over time, reflecting coordinated lateral and vertical stem expansion regulated by developmental processes. Leaf proliferation showed partially decoupled dynamics from stem growth, indicating specialized control over leaf traits. …”
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Where are the data linking infant outcomes, breastfeeding and medicine exposure? A systematic scoping review. by Sue Jordan, Sophia Komninou, Sandra Lopez Leon

“…No studies reported educational or long-term developmental outcomes. The data are too sparse to warrant any firm conclusions, beyond the need for more data. …”
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Examining power dynamics in global health governance using topic modeling and network analysis of Twitter data by Jennifer J Prah, Gian Franco Bermudez

“…Policy documents and developmental assistance for health (DAH) financial data for each actor were collected for the same period.Results We find all 20 actors and the global health system collectively fulfil the three conditions of RAM based on stated and revealed priorities. …”
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