Helicobacter pylori Infection in Persons with Intellectual Disability in Residential Care in Israel by Joav Merrick, Shoshana Aspler, Inessa Dubman

“…At follow-up, clinically all patients had improvement and only seven still had minor complaints (83% treatment success). Persons with developmental disability, intellectual disability, or mental retardation in residential care presenting with severe dyspeptic symptoms had a high incidence of H. pylori infection. …”
Get full text

Melatonin supplementation for the treatment of infantile spasms: protocol for a randomised placebo-controlled triple-blind trial by Jing Wang, Tao Xu, Miao Liu, Jian Chen, Guang Yang, Weiwei Feng, Yulin Sun, Xiuyu Shi, Liping Zou

“…Secondary outcomes include the response rate (the rate of spasms-free), electroencephalogram hypsarrhythmia assessment and the psychomotor development assessment (Denver Developmental Screening Test). Sleep quality and safety will also be assessed.Ethics and dissemination The protocol for this study was approved by the Ethics Committee of Chinese PLA General Hospital (reference number S2020-337-01) and was reported according to the Standard Protocol Items: Recommendations for Interventional Trials statement. …”
Get full text

Batterer typologies: substance use, impulsivity and results of an IPVAW offender treatment program in Spain by Pedro V. Mateo-Fernández, Pedro V. Mateo-Fernández, Pedro V. Mateo-Fernández, Iria Osa-Subtil, Iria Osa-Subtil, Iria Osa-Subtil, Román Ronzón-Tirado, María Elena de la Peña Fernández

“…We We propose a future longitudinal study to throw light on the subsequent developmental paths taken by IPVAW offenders.…”
Get full text

Reducing the Brace Correction Stress on the Secondary Lumbar Curve Results in Excellent Muscle, Bone, and Disc Mechanical Performance: A Musculoskeletal Finite Element Simulation o... by Xiaohui Zhang, Di Wang, Danyu Lv, Jinmiao Lv, Huiyi Tang, Jinlin Qian, Bagen Liao

“…ABSTRACT Objectives The biomechanical mechanism of brace intervention on bone, muscle, and disc should be comprehensively considered for AIS patients. We aimed to developmentally construct a musculoskeletal finite element model of adolescent idiopathic scoliosis to simulate the coupling of corrective forces and analyze the mechanical properties of bone, muscle, and disc. …”
Get full text

Control of two-spotted spider mite, Tetranychus urticae, on strawberry by integrating with cyetpyrafen and Phytoseiulus persimilis by Shan Zhao, Qiuyu Zhao, Xiaoyan Dai, Bing Lv, Ruijuan Wang, Zhenjuan Yin, Feng Zhang, Yan Liu, Long Su, Hao Chen, Li Zheng, Hongmei Li, Lixia Xie, Yifan Zhai

“…The predatory mite, Phytoseiulus persimilis, is a promising biological control agent, preying on all TSSM developmental stages. In this study, we examined the toxicity of six common acaricides on TSSM and P. persimilis, and cyetpyrafen was selected due to its highest relative toxicity value. …”
Get full text

How can urban expansion and ecological preservation be balanced? A simulation of the spatial dynamics of production-living-ecological spaces in the Huaihe River Eco-Economic Belt by Tonghui Yu, Shanshan Jia, Yu Zhang, Xufeng Cui

“…This study utilizes a combination of the Future Land Use Simulation (FLUS) model and the Markov model to analyze how various developmental scenarios might influence the spatial dynamics of the Production-Living-Ecological Spaces (PLES) structure. …”
Get full text

Fetal Cartilage Progenitor Cells in the Repair of Osteochondral Defects by Bruno C. Menarim, DVM, PhD, Chan Hee Mok, PhD, Kirsten E. Scoggin, PhD, Alexis Gornik, DVM, Emma N. Adam, DVM, PhD, Shavahn C. Loux, PhD, James N. MacLeod, VMD, PhD

“…IZN or ANL cells exhibited some potential to recapitulate developmental features during cartilage repair. However, identifying regulatory determinants of IZN and ANL-derived overgrowths is necessary. …”
Get full text

Chinese cabbage orphan gene BR3 confers bolting resistance to Arabidopsis through the gibberellin pathway by Yuting Zhang, Mingliang Jiang, Shurui Sun, Zongxiang Zhan, Xiaonan Li, Zhongyun Piao

“…The expression of BR3 was developmentally regulated and occurred during the seedling and flowering stages. …”
Get full text

Endometriosis does not impact aneuploidy rates of products of conception in IVF population by Huijuan Kong, Wenqian Fan, Tian Ye, Linqing Du

“…Abstract It has been debated whether endometriosis (EMS) adversely affects oocyte quality, potentially leading to a higher incidence of genetically unbalanced embryos or other egg factors that affect the developmental potential. In this study, we explored the effects of endometriosis on risk of chromosomally aberrant in miscarried products of conception (POC) after assisted reproductive treatment (ART), including fresh and frozen cycles. …”
Get full text

Chronic Rapamycin Prevents Electrophysiological and Morphological Alterations Produced by Conditional Pten Deletion in Mouse Cortex by Jason S. Hauptman, Joseph Antonios, Gary W. Mathern, Michael S. Levine, Carlos Cepeda

“…Abnormalities in the mammalian target of the rapamycin (mTOR) pathway have been implicated in numerous developmental brain disorders. While the molecular and histological abnormalities have been described, less is known about alterations in membrane and synaptic excitability with chronic changes in the mTOR pathway. …”
Get full text

Role of Endogenous Hormones on Seed Hardness in Pomegranate Fruit Development by Haoxian Li, Lina Chen, Ruitao Liu, Zhenhua Lu

“…We compared changes in hormones during the development of soft- and hard-seeded varieties in order to identify key hormones and developmental stages that affect seed lignin synthesis and accumulation. …”
Get full text

Novel Compound Heterozygous BBS2 and Homozygous MKKS Variants Detected in Chinese Families with Bardet–Biedl Syndrome by Li Huang, Limei Sun, Zhirong Wang, Songshan Li, Chonglin Chen, Xiaoling Luo, Xiaoyan Ding

“…Bardet–Biedl syndrome (BBS) is a rare multisystem developmental disorder. In this study, we report the genetic causes and clinical manifestations in two Chinese families with BBS. …”
Get full text

Parental Evaluation of a Responsive Parenting Program for Infants with Hearing Loss by Reinhild Glanemann, Karen Reichmuth, Stephanie Brinkheetker, Antoinette am Zehnhoff-Dinnesen, Katrin Neumann

“…Their infants (<i>N</i> = 45) had moderate to complete hearing loss, they were aged 2–20 months, and 40% of them had an additional disease, disorder, and/or developmental delay. Results: Parents reported high levels of satisfaction with the content, didactics, setting, and individual benefits of the intervention, and a high recommendation rate (92%). …”
Get full text

Double-blind, randomised, placebo-controlled trial to evaluate the effectiveness of late gestation oral melatonin supplementation in reducing induction of labour rates in nulliparo... by Miranda Davies-Tuck, Emily Callander, Mary Sharp, Scott W White, Dorota A Doherty, Jane Warland, Zoe Bradfield, Lesley Kuliukas, Monique Rose, Amber Pettitt, Kylie Ekin, JA Keelan

“…Secondary endpoints will include the following: interval between administration of trial medication and birth; a range of maternal and neonatal outcomes, including birth outcomes; breastfeeding on discharge, at 10 days and at 2 months; maternal satisfaction; child developmental outcomes at 2 months of age; and cost-effectiveness of melatonin compared with standard care. …”
Get full text

Examining tolerability, safety, and blinding in 1032 transcranial electrical stimulation sessions for children and adolescents with neuropsychiatric and neurodevelopmental disorder... by Andrea Battisti, Giulia Lazzaro, Luciana Ursumando, Barbara D’Aiello, Valeria Zanna, Floriana Costanzo, Stefano Vicari, Deny Menghini

“…., attention deficit and hyperactivity disorder, developmental dyscalculia) conditions. It compared adverse events (AEs) occurrence between active and sham transcranial electrical stimulation (tES) conditions (i.e., 528 active vs. 504 sham sessions) as well as tDCS and tRNS (i.e., 772 tDCS sessions vs. 260 tRNS sessions), while considering demographic and emotional-behavioural factors. …”
Get full text

Towards PErsonalised PRognosis for children with traumatic brain injury: the PEPR study protocol by Jaap Oosterlaan, Marsh Königs, Job B M van Woensel, Marc Engelen, Marjan E Steenweg, Petra J W Pouwels, Cece C Kooper, Hilgo Bruining, Arne Popma, Dennis R Buis, Maayke Hunfeld

“…Therefore, this study aims to develop prognostic models for the individual outcome of children with TBI in a range of important developmental domains. In addition, the potential added value of advanced neuroimaging data and the use of machine learning algorithms in the development of prognostic models will be assessed.Methods and analysis 210 children aged 4–18 years diagnosed with mild-to-severe TBI will be prospectively recruited from a research network of Dutch hospitals. …”
Get full text

Clinical Features and Genetic Characteristics of XLID Patients With KDM5C Gene Mutations: Insights on Phenotype–Genotype Correlations From 175 Previous Cases and Identification of... by Mohammad‐Reza Ghasemi, Zahra Esmaeilizadeh, Sahand Tehrani Fateh, Hossein Sadeghi, Saman Bagheri, Farzad Hashemi‐Gorji, Morteza Sheikhi Nooshabadi, Rasoul Madannezhad, Toktam Sadat Tavabe Ghavami, Reza Mirfakhraie, Mohammad Miryounesi

“…ABSTRACT Background X‐linked intellectual disability (XLID) is a genetically heterogeneous disorder that results in cognitive impairment and developmental delays. Mutations in the KDM5C gene have been identified as a causative factor in XLID. …”
Get full text

Damage symptoms, development, and reproductive performance of the fall armyworm, Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae) on fodder maize and cob by Hend O. Mohamed, Hassan F. Dahi, Azza A. Awad, Walaa E. Gamil, Bassam F. Fahmy

“…The results of this study could play a significant role in predicting the damage and reproductive performance of FAW in maize fields during their developmental growth, which will further help in developing effective integrated management techniques against this pest.…”
Get full text

Glia control experience-dependent plasticity in an olfactory critical period by Hans C Leier, Alexander J Foden, Darren A Jindal, Abigail J Wilkov, Paola Van der Linden Costello, Pamela J Vanderzalm, Jaeda Coutinho-Budd, Masashi Tabuchi, Heather T Broihier

“…Sensory experience during developmental critical periods has lifelong consequences for circuit function and behavior, but the molecular and cellular mechanisms through which experience causes these changes are not well understood. …”
Get full text

Research priorities for preterm lung health research across the lifespan: a community priority setting partnership by Anne McKenzie, Shannon J Simpson, Naomi R Hemy, Amber Bates, Belinda Frank

“…Participants identified the following top 10: (1) lifelong impacts; (2) interventions, treatments or supports; (3) ongoing lung health follow-up; (4) diagnostic tools, resources and education for primary healthcare providers; (5) resources to inform and empower families; (6) relationship to physical health and developmental issues; (7) preventing and/or treating lung infections; (8) additional supports, resources and research for minority groups; (9) impact on mental well-being; and (10) likelihood of asthma diagnosis.Conclusion Priorities identified through the PSP will be invaluable in informing future research into prematurity-associated lung disease.…”
Get full text