Clinical Report of a 17q12 Microdeletion with Additionally Unreported Clinical Features by Jennifer L. Roberts, Stephanie K. Gandomi, Melissa Parra, Ira Lu, Chia-Ling Gau, Majed Dasouki, Merlin G. Butler

“…Copy number variations involving the 17q12 region have been associated with developmental and speech delay, autism, aggression, self-injury, biting and hitting, oppositional defiance, inappropriate language, and auditory hallucinations. …”
Get full text

A lectin produced by a Streptomyces species targets mammalian pancreatic acinar cells in mice and humans by Janine C. Quijano, Honoka Natsuyama, Alonso Tapia, Karine Bagramyan, Jose A. Ortiz, Jacob Mares, Markus Kalkum, Yoko Fujita-Yamaguchi, Hsun Teresa Ku

“…Together, these results demonstrate that SHA can bind to normal murine and human pancreatic acinar cells and that SHA-binding glycans are developmentally regulated.…”
Get full text

Relationship of Nitrogen Use Efficiency with the Activities of Enzymes Involved in Nitrogen Uptake and Assimilation of Finger Millet Genotypes Grown under Different Nitrogen Inputs by Nidhi Gupta, Atul K. Gupta, Vikram S. Gaur, Anil Kumar

“…Nitrogen responsiveness of three-finger millet genotypes (differing in their seed coat colour) PRM-1 (brown), PRM-701 (golden), and PRM-801 (white) grown under different nitrogen doses was determined by analyzing the growth, yield parameters and activities of nitrate reductase (NR), glutamine synthetase (GS), glutamate synthase; GOGAT, and glutamate dehydrogenase (GDH) at different developmental stages. High nitrogen use efficiency and nitrogen utilization efficiency were observed in PRM-1 genotype, whereas high nitrogen uptake efficiency was observed in PRM-801 genotype. …”
Get full text

Dendritic growth and synaptic organization from activity-independent cues and local activity-dependent plasticity by Jan H Kirchner, Lucas Euler, Ingo Fritz, André Ferreira Castro, Julijana Gjorgjieva

“…We demonstrate that a trade-off between activity-dependent and -independent factors influences dendritic growth and synaptic location throughout development, suggesting that early developmental variability can affect mature morphology and synaptic function. …”
Get full text

Assessing in-vitro models for microglial development and fetal programming: a critical review by Steven Schepanski, Steven Schepanski, Gonza B. Ngoumou, Gonza B. Ngoumou, Claudia Buss, Claudia Buss, Claudia Buss, Claudia Buss, Georg Seifert, Georg Seifert

“…Hofbauer cells, which are fetal macrophages located in the placenta and share a common developmental origin with microglia, are uniquely exposed to prenatal maternal factors and, depending on fetal barrier maturation, exhibit variable epigenetic fidelity. …”
Get full text

The Role of Glucocorticoid Receptors in Dexamethasone-Induced Apoptosis of Neuroprogenitor Cells in the Hippocampus of Rat Pups by Chun-I Sze, Yung-Chieh Lin, Yuh-Jyh Lin, Ting-Hui Hsieh, Yu Min Kuo, Chyi-Her Lin

“…Results. Dex reduced the developmental gain in body weight, but had no effect on brain weight. …”
Get full text

In Silico Analysis of Common Long Noncoding RNAs in Schistosoma mansoni and Schistosoma haematobium by Serhat Sirekbasan, Tugba Gurkok Tan

“…Genetic regulation of the genus Schistosoma, which has different developmental stages throughout its life, is quite complex. …”
Get full text

Collaborative management of severe periodontal-endodontic lesion with intense lip sucking: a case report by Yanfei Sun, Xiaofang Zhao, Mingchao Wang, Xiangkun Sun, Kunzhou Mei, Yameng Zhang, Yanwen Cui, Fang Yang

“…Abstract Background Lip behaviors can lead to maxillofacial developmental disorders such as anterior open bite, posterior crossbite, increased overjet, and a higher risk of developing a Class II malocclusion. …”
Get full text

Seahorse nanos3 plays essential roles in germ cell development in the absence of nanos2 by Lingzhen Chen, Lu Tang, Qiang Lin, Yanhong Zhang

“…More interestingly, nanos3, which is reported to be a female-specific gene, was also highly expressed in male gonads, as well as in the early developmental stages of testes and ovaries. Our results also showed that nanos3 was highly expressed in early meiotic germ cells, and that expression levels of nanos3 were lower in the gonad after TBT exposure. …”
Get full text

Study on early inflorescence development in bread wheat (T. aestivum L.) lines with non-standard SCR-morphotype by O. B. Dobrovolskaya, A. A. Krasnikov, K. I. Popova, P. Martinek, N. Watanabe

“…Wheat lines and forms with altered inflorescence morphology are important genetic resources for the study on the genetic mechanisms underlying plant developmental programs and inflorescence architecture; they are also important for practical use to increase productivity. …”
Get full text

Behind the scenes with genomics researchers by Renata Mont’Alverne, Lori Bradford, Cheryl Buckmaster, Graham Strickert, Jason MacLean, Diane Dupont

“…Emerging topics were grouped into two broad categories akin to Bronfenbrenner’s nested developmental model: microsystem matters, comprising technical advances, barriers, and localized concerns; and macrosystem matters, exploring wider reflections and the philosophies of genomics and society. …”
Get full text

Effects of Nutrient-Fortified Milk-Based Formula on the Nutritional Status and Psychomotor Skills of Preschool Children by Mavil May C. Cervo, Diane S. Mendoza, Erniel B. Barrios, Leonora N. Panlasigui

“…Anthropometric measurements, dietary intake, and psychomotor developmental score were analyzed. Results showed that consumption of two servings of fortified milk a day for twelve weeks significantly increased the height of preschool children by 1.40 cm, weight by 1.35 kg, body mass index by 0.96 kg/m2, mid-upper arm circumference by 0.66 cm, and psychomotor scores by 13.74% more than those children who did not consume fortified milk (p<0.0001). …”
Get full text

Genetic approaches to the investigation of serotonergic neuron functions in animals by U. S. Drozd, E. V. Shaburova, N. N. Dygalo

“…In addition, the review describes inducible models that allow gene expression to be controlled at various developmental stages. Finally, the application of these genetic approaches in optogenetics and chemogenetics provided a new resource for studying the functions, discharge activity, and signal transduction of serotonergic neurons. …”
Get full text

INVESTIGATING THE SCIENTIFIC FOCUS ON ARTIFICIAL INTELLIGENCE'S POTENTIAL IMPACT ON LABOR MARKET by Ludovic DIOSZEGI

“…Ongoing analysis of developmental stages and their potential impacts is essential to propose appropriate directing or regulatory measures. …”
Get full text

Personalized allele-specific antisense oligonucleotides for GNAO1-neurodevelopmental disorder by Inna Shomer, Nofar Mor, Shaul Raviv, Noga Budick-Harmelin, Tanya Matchevich, Sharon Avkin-Nachum, Yoach Rais, Rebecca Haffner-Krausz, Ariela Haimovich, Aviv Ziv, Reut Fluss, Bruria Ben-Ze’ev, Gali Heimer, Denis N. Silachev, Vladimir L. Katanaev, Dan Dominissini

“…GNAO1-associated disorders are ultra-rare autosomal dominant conditions, which can manifest, depending on the exact pathogenic variant in GNAO1, as a spectrum of neurological phenotypes, including epileptic encephalopathy, developmental delay with movement disorders, or late-onset dystonia. …”
Get full text

STUDY OF GERMINATION REGARDING THE COMBAT OF WEEDS IN MEADOWS WITH REFERENCE TO CIRSIUM VULGARE SPECIES by Lisena Piscoran, Teodor Rusu

“…Seed germination is the most important stage in the life cycle of a plant.During seed germination,various metabolic processes are activated that ensure seedling growth and important physiological and biochemical changes occur.Factors acting during seed development (temperature, moisture, burial and microbial damage) can influence subsequent germination performance.Developmental(eg,inflorescence,age) and positional (within or between inflorescences of the parent plant) effects may also be important.In general,C.vulgare is a Euriecia species(species with a high degree of adaptability) common on wet alluvial soils.C vulgare reproduction: pollination takes place by insects (entomogamous pollination) or possibly by wind (anemogamous pollination).They are plants with a biennial reproductive cycle.In the first year they have a single rosette of leaves, while in the second year they bloom completely.They are herbaceous plants that differ from the other biological forms because,being annual,they overcome the adverse season in the form of seeds and are equipped with an erect and often leafless flower axis.…”
Get full text

Between adolescence and adulthood: Emerging adulthood in Serbia by Jojić Antonije, Krstić Ksenija

“…Jeffrey Arnett has defined emerging adulthood (EA) as a developmental period set between adolescence and adulthood. …”
Get full text

Fleece-Lined Whelping Pools Associated with Reduced Incidence of Canine Hip Dysplasia in a Guide Dog Program by Lynna C. Feng, Alexandra Philippine, Elizabeth Ball-Conley, Sarah-Elizabeth Byosiere

“…However, given that CHD is polygenic and multifactorial, environmental factors may impact the expression of this developmental condition. The objective of this original, correlational research was to investigate the relationship between the substrate in the whelping pool used from birth to 3 weeks of age and CHD diagnosis. …”
Get full text

Chloroplast Vesiculation and Induced Chloroplast Vesiculation and Senescence‐Associated Gene 12 Expression During Tomato Flower Pedicel Abscission by Magda Tušek Žnidarič, Maja Zagorščak, Živa Ramšak, Katja Stare, Marko Chersicola, Maruša Pompe Novak, Aleš Kladnik, Marina Dermastia

“…ABSTRACT Abscission is a tightly regulated process in which plants shed unnecessary, infected, damaged, or aging organs, as well as ripe fruits, through predetermined abscission zones in response to developmental, hormonal, and environmental signals. Despite its importance, the underlying mechanisms remain incompletely understood. …”
Get full text

Exploring the Potential Effectiveness of <i>Croton tiglium</i> Oil and Its Nano-Emulsion on <i>Earias insulana</i> (Lepidoptera: Nolidae) by Karima S. Khater, Marwa M. Abd-Elrhmman, Zeinab M. E. A. Said, Ali A. El-Sayed, Abdelhadi A. I. Ali, Lamya Ahmed Alkeridis, Laila A. Al-Shuraym, Jingwen Wang, Qichun Zhang, Ahmed A. A. Aioub

“…We assessed their biological effects across different developmental stages and performed histological and ultrastructural examinations. …”
Get full text