Development and Validation of an UHPLC-MS/MS Method for Quantification of DMAG in Rat Plasma and Its Application in a Preliminary Pharmacokinetic Study in Thrombocytopenia Rats by Yan Li, Yuqing Wang, Zhiqiang Zhao, Yunxia Li, Cheng Peng, Jianming Wu

“…Overall, we successfully developed a reliable UHPLC-MS/MS method for determining DMAG levels in rat plasma. The pharmacokinetic difference could be attributed to the pathological state of the thrombocytopenia rats, which may affect the absorption, distribution, metabolism, and excretion of DMAG. …”
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Integrated Microbiome and Metabolome Analysis Reveals Correlations Between Gut Microbiota Components and Metabolic Profiles in Mice With Mitoxantrone-Induced Cardiotoxicity by Zhang Q, Liang D, Zhang C, Ye L, Sun P, Zhu H, Zhao Y, Li Y, Guan Y, Zhang H

“…Plasma CK-MB and LDH levels were determined, and the heart tissue histopathology was assessed, followed by utilizing an integrated liquid chromatography-mass spectrometry (LC-MS)-based heart metabolomics study alongside the 16S ribosomal RNA (rRNA) sequencing method to assess MTX impact on GM and CM profiles in mice, establishing associations between GM and CM profiles through the Pearson correlation coefficient calculation.Results: MTX caused CK-MB and LDH level elevations and cardiotoxicity in our mouse model. …”
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Genetically and chemically intraspecific variations of Ficus hirta provide novel insights into its protection and utilization by Jianling Chen, Qianqian Liu, Huihong Wang, Zhi Chao, Enwei Tian

“…In this study, we conducted an evaluation of the chloroplast DNA (cpDNA) genetic diversity and population structure of F. hirta in southern China, and further evaluated its medicinal quality based on HPLC fingerprinting and the content determination of the active components. Results F. hirta presented high overall genetic diversity (Hd = 0.792) for cpDNA but low genetic diversity (Hd = 0.000 ~ 0.467) within populations. …”
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Efek Electro Convulsive Therapy (ECT) terhadap Daya Ingat Pasien Skizofrenia di RSJ Prof. HB. Sa’anin Padang by Ikky Nabila Nandinanti, Yaslinda Yaunin, Siti Nurhajjah

“…The objective of this study was to determine the effects of ECT on memory schizophrenic patients. …”
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A Randomized Placebo-Controlled N-of-1 Trial: The Effect of Proton Pump Inhibitor in the Management of Gastroesophageal Reflux Disease by Fernando Sierra-Arango, D. M. Castaño, Jennifer D. Forero, Erika D. Pérez-Riveros, Gerardo Ardila Duarte, Maria L. Botero, Andres Cárdenas, Jose De la Hoz-Valle

“…D’agostino–Pearson and Wilcoxon test were used to determine normal or nonnormal distribution and compare both treatments, respectively, both with a significant statistical difference of p<0.05. …”
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Hubungan Tingkat Pengetahuan Ibu dengan Pemberian Imunisasi Dasar Lengkap pada Bayi di Kelurahan Parupuk Tabing Wilayah Kerja Puskesmas Lubuk Buaya Kota Padang Tahun 2013 by Atika Putri Dewi, Eryati Darwin, Edison .

“…<br />Kata kunci: imunisasi dasar lengkap, pengetahuan</p><p>Abstract<br />In the city of Padang immunization coverage was 88.1% with the lowest coverage in the Lubuk Buaya Public Health Centre was 81.8 % .Village of Parupuk Tabing was the lowest coverage and highest drop-out rate of 12.9% in 2012. This study aims to determine relationshipof the level of mother's knowledge with base complete infant immunization in the Village of Parupuk Tabing Lubuk Buaya Public Health Centre working area in the City of Padang in 2013. …”
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Faktor-Faktor yang Berhubungan dengan Pola Pemberian ASI Eksklusif di Wilayah Kerja Puskesmas Bungus Tahun 2014 by Selvi Indriani Nasution, Nur Indrawati Liputo, Mahdawaty Masri

“…The objective of this study was to determine  any  factors associated to exclusive breastfeeding in the Work Area Health Bungus 2014. …”
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Identification of Behavioral, Clinical, and Psychological Antecedents of Acute Stimulant Poisoning: Development and Implementation of a Mixed Methods Psychological Autopsy Study by Marley Antolin Muñiz, Vanessa M McMahan, Xochitl Luna Marti, Sarah Brennan, Sophia Tavasieff, Luke N Rodda, James Knoll, Phillip O Coffin

“…We selected deaths determined to be due to acute poisoning from cocaine or methamphetamine, which occurred 3‐12 months prior and were not attributed to suicide or homicide. …”
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Impact of Low Inclusion Rate of Olive Cake in Dairy Cow Rations on Uterine Health and Fertility Indices During Early Lactation by Ioannis Nanas, Themistoklis Giannoulis, Eleni Dovolou, Ilias Giannenas, Georgios S. Amiridis

“…Blood samples were examined to determine the β-hydroxybutyric acid (BHBA), acute phase proteins (haptoglobin [Hpt] and serum amyloid A [SAA]), progesterone, and pregnancy-associated glycoproteins concentrations. …”
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Frekuensi HBsAg Positif pada Uji Saring Darah di Palang Merah Indonesia Cabang Padang Tahun 2012 by Nadia Ventiani, Susila Lastri, Dian Pratiwi

“…The objective of this study was to determine the frequency of positive HBsAg in the screening test of the blood donors. …”
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THE CHARACTERISTICS OF MIRNA BINDING SITES IN MRNA OF ZFHX3 GENE AND ITS ORTHOLOGS by A. М. Kondybayeva, A. N. Akimniyazova, S. U. Kamenova, A. Т. Ivashchenko

“…The characteristics of miRNA–mRNA interaction were determined using MirTarget software. It has been shown that the first TNR in mRNA of the human ZFHX3 gene consists of the seven consecutive miR-12-32603-3p binding encoding polyGlu. …”
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Klasifikasi Kinerja Akademik Siswa Menggunakan Neighbor Weighted K-Nearest Neighbor dengan Seleksi Fitur Information Gain by Rizky Adinda Azizah, Fitra Bachtiar, Sigit Adinugroho

“…In this research, the secondary data is used to determine student performance through a classification. …”
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High Concentration of Glucose Increases Reactive Oxygen Species Generation and Apoptosis Induced by Endoplasmic Reticulum Stress Pathway in Rabbit Corneal Epithelial Cells by Jiajun Lu, Minjie Sheng, Panpan Yao, Chaochao Ran, Hao Liu, Li Chen, Rui Liu, Bing Li

“…The expressions of PERK, p-PERK, Akt, p-Akt, and CHOP were determined by western blot, and the cell viability was measured by Cell Counting Kit-8 (CCK-8). …”
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Antibiotic and Disinfectant Susceptibility Patterns of Bacteria Isolated from Farmed Fish in Kirinyaga County, Kenya by Daniel W. Wanja, Paul G. Mbuthia, Robert M. Waruiru, Lilly C. Bebora, Helena A. Ngowi, Philip N. Nyaga

“…The aim of the current study was to determine the susceptibility patterns of bacteria isolated from fish, with respect to some commonly used antibiotics and disinfectants. …”
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Correlation between Preoperative Platelet Count/(Lymphocyte Count × Prealbumin Count) Ratio and the Prognosis of Patients with Gastric Cancer Undergoing Radical Operation by Yi Liu, Yanguang Yang, Guomei Tai, Feng Ni, Cenming Yu, Wenjing Zhao, Ding Wang

“…According to the area under the Receiver operating characteristic curve, the predictive value of the preoperative PLPR for the 5-year overall survival (OS) of gastric cancer was determined, and the best cut-off value of the ratio was corresponding to the maximum value of Yoden index. …”
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Soil-plant-animal relationships and their effect on pasture-based milk production in Hacienda Cuba, Colombia by María A. López G., Ana G. Quintero M., Juan J. Zúñiga E., Felipe Vélez S., Juan F. Naranjo R., Óscar A. Sáenz R., Andrés F. Pérez R.

“…Subsequently, the milk production potential of the animals was determined based on the forage diet provided, as well as the impact and quantification of intensification practices, such as strategic supplementation, on buffalo milk production. …”
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Incidence of Malignancies and the Association with Biological Disease-Modifying Antirheumatic Drugs in Japanese Patients with Rheumatoid Arthritis: A Time-Dependent Analysis from t... by Masayoshi Harigai, Eiichi Tanaka, Eisuke Inoue, Ryoko Sakai, Naohiro Sugitani, Shigeyuki Toyoizumi, Naonobu Sugiyama, Hisashi Yamanaka

“…Using patient registry data, we determined malignancy risk, stratified by bDMARD use, among Japanese patients with RA versus the Japanese general population and investigated whether bDMARD use is a time-dependent risk factor for the development of malignancy. …”
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Evaluation of the Back-in-Action test Battery In Uninjured High School American Football Players by Marcel Rohde, Alina Ruhlemann, Andre Busch, Ulrich Grunwald, Marcus Jaeger, Constantin Mayer

“… # Purpose The aim of the study was to determine the performance of under 18 American football players on the BIA to establish pre-injury sport specific benchmarks for future RTS testing and to compare these values to data from an age-matched reference group…”
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Barriers and Facilitators in Implementing a Telemonitoring Application for Patients With Chronic Kidney Disease and Health Professionals: Ancillary Implementation Study of the NeLL... by Marion Delvallée, Abdallah Guerraoui, Lucas Tchetgnia, Jean-Pierre Grangier, Nassira Amamra, Anne-Laure Camarroque, Julie Haesebaert, Agnès Caillette-Beaudoin

“…The adoption of telemonitoring was assessed based on the frequency with which patients connected to the telemonitoring device. Determinants of telemonitoring use were analyzed using nonparametric tests, specifically the Wilcoxon-Mann-Whitney and Kruskal-Wallis tests. …”
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Novel pyroptosis-immune-related lncRNA signature exhibits a distinct immune cell infiltration landscape in breast cancer by Dedi Kong, Dedi Kong, Hongju Cheng, Meihong Wang

“…IntroductionThis study investigated pyroptosis- and immunity-related long non-coding RNAs (lncRNAs) to identify promising therapeutic targets for breast cancer (BC), and constructed lncRNA signatures to determine the prognosis and immunotherapy responses of BC patients.MethodsPearson’s correlation coefficient was used to identify pyroptosis- and immune-related differentially expressed lncRNAs (DE-pyrolncRNAs and DE-ImmlncRNAs, respectively). …”
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