HDAC10 and its implications in Sézary syndrome pathogenesis by Monika Pieniawska, Karolina Rassek, Bogumiła Skwara, Magdalena Żurawek, Iwona Ziółkowska-Suchanek, Lydia Visser, Monique Lodewijk, Małgorzata Sokołowska-Wojdyło, Małgorzata Sokołowska-Wojdyło, Berenika Olszewska, Roman J. Nowicki, Roman J. Nowicki, Tomasz Stein, Aleksandra Dańczak-Pazdrowska, Adriana Polańska, Marta Szymoniak-Lipska, Natalia Rozwadowska, Katarzyna Iżykowska

“…In this study we aimed to determine the role of HDAC10 in SS, focusing on its cellular localization, role in cell growth, and therapeutic potential. …”
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Antimicrobial susceptibilities of oral Neisseria from men on HIV pre-exposure prophylaxis in Hanoi, Vietnam by Huan Vinh Dong, Paul Adamson, Dieu Hoa Pham, Quynh Hoa Pham, Hai Ha Long Le, Loc Quang Pham, Hao Thi Minh Bui, Giang Minh Le, Jeffrey D. Klausner

“…Minimum inhibitory concentrations (MICs) to azithromycin, ceftriaxone, cefixime, and doxycycline were determined using Etests. Results: There were 42 male participants, the median age was 26 years and 29% (n = 12) reported using antibiotics in the past 6 months. …”
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Predicting the risk of heart failure after acute myocardial infarction using an interpretable machine learning model by Qingqing Lin, Qingqing Lin, Wenxiang Zhao, Wenxiang Zhao, Hailin Zhang, Hailin Zhang, Wenhao Chen, Sheng Lian, Qinyun Ruan, Qinyun Ruan, Zhaoyang Qu, Zhaoyang Qu, Yimin Lin, Yimin Lin, Dajun Chai, Dajun Chai, Dajun Chai, Dajun Chai, Xiaoyan Lin, Xiaoyan Lin, Xiaoyan Lin, Xiaoyan Lin

“…In addition, we used the Shapley Additive Explanations (SHAP) value to determine the importance of the selected features and interpret the optimal model.ResultsA total of 1220 AMI patients were included and 244 (20%) patients developed HF during follow-up. …”
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Genetic Association and Expression Correlation between Colony-Stimulating Factor 1 Gene Encoding M-CSF and Adult-Onset Still’s Disease by Yi-Ming Chen, Wei-Ting Hung, Wan-Chun Chang, Chia-Wei Hsieh, Wen-Hung Chung, Joung-Liang Lan, Ning-Rong Gung, Yun-Shien Lee, Der-Yuan Chen, Shuen-Iu Hung

“…The plasma concentrations of associated gene product were determined. The GWAS, replication, and combined sample analysis confirmed that SNP rs11102024 on 5′-upstream of CSF1 encoding macrophage colony-stimulating factor (M-CSF) was associated with AOSD (P=1.20×10-8, OR (95% CI): 3.28 (2.25~4.79)). …”
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Unleashing the potential of geostationary satellite observations in air quality forecasting through artificial intelligence techniques by C. Zhang, X. Niu, H. Wu, Z. Ding, K. L. Chan, J. Kim, T. Wagner, C. Liu, C. Liu, C. Liu

“…Evaluation against ground-based measurements demonstrates that GeoNet accurately predicts diurnal variations and spatial distribution details of next-day NO<span class="inline-formula">₂</span> pollution, yielding a coefficient of determination of 0.68 and a root mean square of error of 12.31 <span class="inline-formula">µg</span> m<span class="inline-formula">⁻³</span>, significantly surpassing traditional air quality model forecasts. …”
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Brain radiotherapy and dorsal vagal complex irradiation: A new organ at risk to decrease radiation-induced nausea and vomiting? by Valentine Caspar, Nicolas Giraud, Thomas Charleux, Arnaud Beddok, Brieuc Bernard, Maelle Martin, Juliette Thariat, Aymeri Huchet, Véronique Vendrely, Charles Dupin

“…The objective of our study was to determine an association between mean dose to the DVC and nausea. …”
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Oncolytic peptide LTX-315 induces anti-pancreatic cancer immunity by targeting the ATP11B-PD-L1 axis by Meng Wang, Xing Huang, Tingbo Liang, Tianyu Tang, Gang Zhang, Minghao Lu, Zhengtao Hong, Junming Huang, Xiao Zhi

“…The expression of programmed cell death ligand 1 (PD-L1) largely determines the efficacy and effectiveness of cancer immunotherapies targeting this specific immune checkpoint. …”
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An improved statistical bias correction method for Global Climate Model (GCM) precipitation projection: A case study on the CMCC-CM2-SR5 model projection in China’s Huaihe River Ba... by Yuning Luo, Ke Zhang, Wen Wang, Xinyu Chen, Jin Feng, Haijun Wang, Wei Liu, Cheng Guo, Cuiying Chen, Xiaozhong Wang

“…The LS-EDCDF method incorporates recurrence periods and least squares with the determination of transfer functions relating observation to model simulation. …”
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Comparative analysis of feeding strategies and post mortem aging time on the oxidative status and color of the longissimus thoracis et lumborum muscle in Braford steers by María Sofía Castaño Ledesma, Gustavo Adolfo Palma, Gustavo Adolfo Palma, Claudio Darío Borsarelli, Claudio Darío Borsarelli, María Sumampa Coria, María Sumampa Coria

“…The content of heme pigment was determined by a spectrophotometric assay, while the fluorescence fingerprint of beef was evaluated by fluorescence spectroscopy excitation-emission matrices (FEEM). …”
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Diagnostic investigation, intervention, and outcome for post-subtotal gastrectomy patients who present with jaundice by Duan Wang, Duan Wang, Liang Zhu, Fanyi Kong, Fanyi Kong, Yingyu Pan, Yingyu Pan, Wei Liu, Xuan Wang, Weidong Pan, Jian Cao, Qiang Xu, Dong Wu, Dong Wu, Dong Wu

“…PET/CT was superior to MRI/MRCP and contrast-enhanced CT in determining lesion extensiveness. Percutaneous transhepatic cholangial drainage (PTCD) was the preferred method for managing obstructive jaundice. …”
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Outcomes in Catheter Ablation of Sustained Ventricular Tachycardia in Myocarditis Compared with Ischemic Heart Disease by Sheng Su, Le Li, Xi Peng, Likun Zhou, Zhuxin Zhang, Yulong Xiong, Zhenhao Zhang, Mengtong Xu, Yan Yao

“…Background: The substrates for arrhythmias in myocarditis and ischemic heart disease (IHD) are different, but it is yet to be determined whether there is a difference in outcomes following catheter ablation (CA) for ventricular tachycardia (VT) associated with these two conditions. …”
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Thyroid Stimulating Hormone Is Increased in Hypertensive Patients with Obstructive Sleep Apnea by Nanfang Li, Mulalibieke Heizhati, Chao Sun, Suofeiya Abulikemu, Liang Shao, Xiaoguang Yao, Yingchun Wang, Jing Hong, Ling Zhou, Lei Wang, Yu Zhang, Weiwei Zhang

“…Methods. 517 hypertensives were cross-sectionally studied. OSA was determined by polysomnography and thyroid function by standard methods. …”
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Characteristic of the active substance of the Saccharomyces cerevisiae preparation having radioprotective properties by G. S. Ritter, V. P. Nikolin, N. A. Popova, A. S. Proskurina, P. E. Kisaretova, O. S. Taranov, T. D. Dubatolova, E. V. Dolgova, E. A. Potter, S. S. Kirikovich, Y. R. Efremov, S. I. Bayborodin, M. V. Romanenko, M. I. Meschaninova, A. G. Venyaminova, N. A. Kolchanov, S. S. Bogachev

“…The newly formed cell population restores the hematopoietic and immune systems, which determines the survival of lethally irradiated animals.…”
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Association between Irisin, hs-CRP, and Metabolic Status in Children and Adolescents with Type 2 Diabetes Mellitus by Leticia Elizondo-Montemayor, Adrian M. Gonzalez-Gil, Oscar Tamez-Rivera, Carla Toledo-Salinas, Mariana Peschard-Franco, Nora A. Rodríguez-Gutiérrez, Christian Silva-Platas, Gerardo Garcia-Rivas

“…The objective of this study was to determine irisin plasma concentration and its association with metabolic and adiposity markers and with hs-CRP, a surrogate marker of inflammation used in clinical practice, in a pediatric population with T2DM. …”
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Features of the functioning of the hypothalamic-pituitary-thyroid axis in mice with Lewis carcinoma on the background of induced hyperthyroidism by E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, I. V. Neskubina, E. I. Surikova, A. I. Shikhlyarova, L. K. Trepitaki, M. A. Gusareva, I. A. Udalenkova, E. O. Vasilieva, N. D. Cheryarina, V. V. Pozdnyakova

“…On the 25th day after tumor transplantation, the level of thyrotropin- releasing hormone (TRH), thyroid- stimulating hormone (TSH), triiodothyronine (T3), total and free thyroxine (T4, FT4) was determined in the homogenates of GGT organs and in blood serum.Results. …”
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Survival outcome prediction of esophageal squamous cell carcinoma patients based on radiomics and mutation signature by Ting Yan, Zhenpeng Yan, Guohui Chen, Songrui Xu, Chenxuan Wu, Qichao Zhou, Guolan Wang, Ying Li, Mengjiu Jia, Xiaofei Zhuang, Jie Yang, Lili Liu, Lu Wang, Qinglu Wu, Bin Wang, Tianyi Yan

“…Results A total of 8 CT features were selected for multivariate Cox regression analysis to determine whether the Rad-score was significantly correlated with OS. …”
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The Global RAdical Cystectomy Evaluation and Management (GRACEM) pathway: single‐centre prospective observational cohort study protocol by Bruno Bernardini, Federico Piccioni, Manuele Pastore, Paolo Casale, NicolòMaria Buffi, Giovanni Lughezzani, Massimo Lazzeri, Alberto Saita, Maria Vittoria Fantacci, Stefano Mancon, Filipo Dagnino, Roberto Contieri, Pietro Brin, Stefano Mancin, Andrea Gobbo, Maria Rosaria Martucci, Giovanna Cerina, Sara Ghirmai, Ezio Lanza, Giulia Goretti, Giorgio Ferruccio Guazzoni, Rodolfoi Hurle

“…The purpose of the study is to determine whether a multifaceted prevention programme that tailors interventions to the syndromic components of frailty can improve postoperative morbidity and recovery time for patients. …”
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Deep eutectic solvent enhances antibacterial activity of a modular lytic enzyme against Acinetobacter baumannii by Aleksandra Maria Kocot, Tomasz Swebocki, Karolina Ciemińska, Adrianna Łupkowska, Małgorzata Kapusta, Dennis Grimon, Ewa Laskowska, Anna-Karina Kaczorowska, Tadeusz Kaczorowski, Rabah Boukherroub, Yves Briers, Magdalena Plotka

“…The bioinformatic analysis allowed us to determine the spatial architecture of MLE-15, whose components were bactericidal peptide cecropin A connected via a flexible linker to the cell wall binding domain (CBD) of mesophilic 201ϕ2 − 1 endolysin and catalytic domain (EAD) of highly thermostable Ph2119 endolysin. …”
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Signatures of H3K4me3 modification predict cancer immunotherapy response and identify a new immune checkpoint-SLAMF9 by Tao Fan, Chu Xiao, Ziqin Deng, Shuofeng Li, He Tian, Yujia Zheng, Bo Zheng, Chunxiang Li, Jie He

“…Importantly, this risk-score system showed satisfactory predictive performance for the ICB therapy responses of patients suffering from several cancer types, and we identified that SLAMF9 was one of the immunosuppressive phenotype and immunotherapy resistance-determined genes of H3K4me3-RS. The mice melanoma model showed Slamf9 knockdown remarkably restrained cancer progression and enhanced the efficacy of anti-CTLA-4 and anti-PD-L1 therapies by elevating CD8 + T cell infiltration. …”
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Tigers and Their Prey in Bukit Rimbang Bukit Baling: Abundance Baseline for Effective Wildlife Reserve Management by Febri Anggriawan Widodo, Stephanus Hanny, Eko Hery Satriyo Utomo, Zulfahmi Zulfahmi, Kusdianto Kusdianto, Eka Septayuda, Tugio Tugio, Effendy Panjaitan, Leonardo Subali, Agung Suprianto, Karmila Parakkasi, Nurchalis Fadhli, Wishnu Sukmantoro, Ika Budianti, Sunarto Sunarto

“…The results suggested that human disturbance strongly determine the density of tigers in the area, more than prey availability. …”
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