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361
Recent advances in nanotechnology for Parkinson’s disease: diagnosis, treatment, and future perspectives
Published 2025-01-01“…Parkinson’s disease is a progressive neurodegenerative disease that destroys substantia nigra dopaminergic neurons, causing tremors, bradykinesia, rigidity, and postural instability. …”
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362
Improving ferroptosis-mediated immunotherapy for colorectal cancer through lysosome-targeted photodynamic therapy
Published 2025-04-01“…Upon internalized by cancer cells, TLA was specifically accumulated in lysosome, and which would destroy the integrity of lysosomal membranes and inhibit protective autophagy upon exposure to light irradiation. …”
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363
Diagenesis and Fluid Flow Variability of Structural Heterogeneity Units in Tight Sandstone Carrier Beds of Dibei, Eastern Kuqa Depression
Published 2017-01-01“…Ductile grains or eogenetic calcite cements destroy the reservoir quality of tight compacted or tight carbonate-cemented sandstones. …”
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364
Cyclooxygenase-2/prostaglandin E2 inhibition remodulated photodynamic therapy-associated immunosuppression for enhanced cancer immunotherapy
Published 2025-04-01“…Photodynamic therapy (PDT) directly destroys cancer cells by producing reactive oxygen species (ROS), and enhances the immunogenicity of ''cold'' tumors by inducing immunogenic cell death (ICD), thereby promoting T cell development against tumors. …”
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365
A two-patch prey-predator model with predator dispersal driven by the predation strength
Published 2017-07-01“…Our analytical results combined with bifurcation diagrams suggest that: (1) dispersal may stabilize or destabilize the coupled system; (2) dispersal may generate multiple interior equilibria that lead to rich bistable dynamics or may destroy interior equilibria that lead to the extinction of predator in one patch or both patches; (3) Under certain conditions, the large dispersal can promote the permanence of the system. …”
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366
Characterization of the Prediabetic State in a Novel Rat Model of Type 2 Diabetes, the ZFDM Rat
Published 2015-01-01“…As islet architecture was destroyed with age in ZFDM rats, a combination of severe insulin resistance, diminished insulin secretory response to incretin, and intrinsic fragility of the islets may cause the development of T2D in this strain.…”
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367
Preparation of NiCr/YSZ two-layered burn-resistant coating on γ-TiAl alloys based on plasma surface metallurgy and ion plating methods
Published 2021-01-01“…The high-energy laser beam destroyed the surface of γ-TiAl alloy, forming protruding combustion products in ablation zone and splashing residues around ablation zone. …”
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368
A deep learning ICDNET architecture for efficient classification of histopathological cancer cells using Gaussian noise images
Published 2025-01-01“…To address this issue, this study introduces a new hybrid network model, termed ICDNET, designed to fuse global and local features without destroying the integrity of the feature data, thus enhancing the accuracy of medical image classification. …”
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369
Traumatic Brain Injury and Stem Cell: Pathophysiology and Update on Recent Treatment Modalities
Published 2017-01-01“…In the acute phase, brain tissue destroyed upon impact includes neurons, glia, and endothelial cells, the latter of which makes up the blood-brain barrier. …”
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370
Influence of Incremental Impact on the Damage of Coal-Rock under Unidirectional Constraint
Published 2019-01-01“…The cumulative damage degree of coal-rock decreases with the increase of axial pressure, and the number of impact needed to destroy coal-rock is increased. In addition, the damage model of coal-rock was proposed, and the criterion of coal-rock damage was obtained, which shows that the damage degree of coal-rock increases with the increase of impact load and decreases with the increase of static axial load.…”
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371
Respiratory Epithelium Lined Cyst of the Maxilla: Differential Diagnosis
Published 2017-01-01“…It could also be an unusual radicular cyst in which the stratified squamous epithelium was destroyed by inflammation and replaced by a respiratory epithelium of the maxillary sinus.…”
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372
Ultrastructure of Placenta of Gravidas with Gestational Diabetes Mellitus
Published 2015-01-01“…On TEM, the distinct ultrastructural alterations indicating the degeneration of terminal villi were found in the GDM placentas as follows: thickening of the basal membrane (BM) of vasculosyncytial membrane (VSM) and the VSM itself, significantly fewer or even absent syncytiotrophoblastic microvilli, swollen or completely destroyed mitochondria and endoplasmic reticulum, and syncytiotrophoblasts with multiple vacuoles. …”
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373
VMLP neural network design using optimization algorithms to predict spider suspend (Case Study: Watershed Dam Kardeh)
Published 2018-06-01“…One of the most important processes of erosion and sediment transport in streams is the river most complex engineering issues.this process special effects on water quality indices, action suburbs floor and destroyed much damage to the river and also into the development plans Lack of continuity sediment sampling and measurement of many existing stations. due to the low number of hydrometric stations in Iran and the lack of continuity of sediment sampling and measuring in many existing stations, on one hand the exact amount of sediment load in many rivers in the country is not available and because of differences in climatic, hydrological and topographical conditions in the country, on the other hand, the preparation and calibration of sediment Erosion Models different regions, is unavoidableCalibration models of erosion and sedimentation in different locations is difficult and requires financial capital andthe time . the But evolutionary optimization algorithm able to resolve this problems of mathematical and experimental methods in this paper, a new optimization algorithm spiders can be made to education And the evolutionary pattern for input (discharge and precipitation) and rain-gauge gauging stations and Watershed Kardeh designated evolutionary algorithms and artificial network performance for 24 year 24-year dam catchment Kardeh for the period studied. …”
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374
Enhancing Mechanical and Thermal Properties of Polyurethane Rubber Reinforced with Polyethylene Glycol-g-Graphene Oxide
Published 2019-01-01“…The reason was that the hydrogen bond interactions between MGO and PUR were destroyed and the hidden length was released during the strain process. …”
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375
Laser Irradiation Alters the Expression Profile of Genes Involved in the Extracellular Matrix In Vitro
Published 2014-01-01“…Healing may be impaired if some of these components are destroyed. Photobiostimulation has demonstrated a stimulatory response in biological processes. …”
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376
Construction and Analysis of Emotion Computing Model Based on LSTM
Published 2021-01-01“…This was 13% lower than in the ALL-LSTM model, indicating that inappropriate feature extraction methods could destroy the timing of EEG signals. LSTM can be used to thoroughly examine EEG signal timing and preprocessed EEG data. …”
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377
Pre-trial investigation in the de-occupied territories: normative regulation and prospects for implementation
Published 2024-06-01“…The issue of the procedure for carrying out criminal proceedings in which materials are lost, in particular destroyed in the occupied territory, is also not defined. …”
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378
Load-Bearing Capacity of Podium Frame for Translucent Atrium Roof
Published 2024-12-01“…The test was carried out until the sample was destroyed. Results. The load-bearing capacity of the podium frame made of fiberglass has been determined. …”
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379
Effect of Hydrolysate Derived from Subcritical Seawater Treatment of Buckwheat Waste on the Growth of Lettuce (<i>Lactuca sativa</i> L.)
Published 2025-01-01“…The X-ray diffraction of the residual solids showed that the structure of BW was destroyed. Compared with seawater, the hydrolysate contained higher amounts of elements beneficial to plant growth, such as N, P, K, and organic compounds such as phenolics and sugars, as a result of the degradation of BW caused by the SST. …”
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380
THE METHODOLOGY OF COST MANAGEMENT IN THE MODERN SOCIETY
Published 2017-04-01“…The top-down administrative system for industrial enterprises' activity and cost management, which functioned in the USSR, is destroyed even in the 90's of past century, and industrial enterprises, large companies preserved only the separate elements of cost management system, they mainly use the methods of limitation and expenditures control, while the integrated system for expenditures management is necessary. …”
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